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Query: NC_017372:902043:903349 Helicobacter pylori India7 chromosome, complete genome

Start: 903349, End: 904485, Length: 1137

Host Lineage: Helicobacter pylori; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). It was only recently discovered (1983) by two Australians (Warren and Marshall) that this organism was associated with peptic ulcers. It is one of the most common chronic infectious organisms, and is found in half the world's population. This organism attacks the gastric epithilial surface, resulting in chronic gastritis, and can cause more severe diseases including those that lead to gastric carcinomas and lymphomas, peptic ulcers, and severe diarrhea. It is an extracellular pathogen that persists in the gastric environment, which has a very low pH, by production of the urease enzyme, which converts urea to ammonia and carbon dioxide, a process which can counteract the acidic environment by production of a base. The toxins include cytolethal distending toxin, vacuolating cytotoxin (VacA) that induces host epithelial cell apopoptosis (cell death), and the cytotoxin associated antigen (CagA) which results in alteration to the host cell signalling pathways. The CagA protein is translocated into host cells by a type IV secretion system encoded by the cag pathogenicity island.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_014256:636000:6502186502186513541137Helicobacter pylori B8 chromosome, complete genomeputative conserved potassium channel protein0695
NC_010698:870312:8727788727788739141137Helicobacter pylori Shi470, complete genomeputative potassium channel protein0692
NC_007575:1663088:1681803168180316829391137Sulfurimonas denitrificans DSM 1251, complete genomehypothetical protein8e-101367
NC_014166:2217790:2230804223080422319341131Arcobacter nitrofigilis DSM 7299 chromosome, complete genomeIon transport 2 domain-containing protein4e-86318
NC_013171:1194500:1207194120719412082011008Anaerococcus prevotii DSM 20548, complete genomeTrkA-N domain protein3e-25116
NC_010003:605961:6098536098536108931041Petrotoga mobilis SJ95, complete genomeTrkA-N domain protein3e-1996.3
NC_016616:2997348:2997348299734829983851038Dechlorosoma suillum PS chromosome, complete genomeK+ transport system, NAD-binding component4e-1892.4
NC_015167:569569:5961235961235971361014Cellulophaga lytica DSM 7489 chromosome, complete genomeTrkA-N domain-containing protein1e-1790.9
NC_009932:39348:4051240512415701059Acaryochloris marina MBIC11017 plasmid pREB7, complete sequenceTrkA family potassium uptake protein , putative6e-1788.6
NC_015320:1342105:137401513740151375001987Archaeoglobus veneficus SNP6 chromosome, complete genomeTrkA-N domain-containing protein7e-1788.6
NC_011296:801612:8023268023268033481023Thermodesulfovibrio yellowstonii DSM 11347, complete genomepotassium uptake protein, TrkA family5e-1685.9
NC_014122:205112:220070220070221065996Methanocaldococcus infernus ME chromosome, complete genomeTrkA-N domain protein8e-1685.1
NC_009616:1604276:1621305162130516223241020Thermosipho melanesiensis BI429 chromosome, complete genomeTrkA domain-containing protein7e-1272
NC_014935:711765:7131957131957147751581Nitratifractor saLSUginis DSM 16511 chromosome, complete genometrka-n domain protein7e-1065.1
NC_009662:837500:8607008607008622801581Nitratiruptor sp. SB155-2, complete genomepotassium channel protein1e-0964.7
NC_007355:3979729:4001968400196840030111044Methanosarcina barkeri str. fusaro chromosome 1, complete sequencepotassium channel protein4e-0756.2
NC_015954:2289717:2291317229131722930051689Halophilic archaeon DL31 chromosome, complete genomeTrkA-N domain-containing protein4e-0652.8
NC_013364:1596278:1602395160239516036481254Escherichia coli O111:H- str. 11128, complete genomevoltage-gated potassium channel protein Kch6e-0652.4
NC_007384:2007467:2026020202602020272731254Shigella sonnei Ss046, complete genomeputative potassium channel protein6e-0652.4
NC_009801:1392696:1397878139787813991311254Escherichia coli E24377A, complete genomepotassium channel protein kch6e-0652.4