Pre_GI: BLASTP Hits

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Query: NC_017328:303987:321809 Shigella flexneri 2002017 chromosome, complete genome

Start: 321809, End: 322249, Length: 441

Host Lineage: Shigella flexneri; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This organism, along with Shigella sonnei, is the major cause of shigellosis in industrialized countries and is responsible for endemic infections. This genus is named for the Japanese scientist (Shiga) who discovered them in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. Human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, and over 1 million deaths worldwide are attributed to them. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. Extremely virulent organisms that require very few cells in order to cause disease. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_013941:975353:992646992646993086441Escherichia coli O55:H7 str. CB9615 chromosome, complete genomehypothetical protein2e-81300
NC_008563:1175035:119108411910841191524441Escherichia coli APEC O1, complete genomehypothetical protein2e-81300
NC_004431:1401681:141716214171621417602441Escherichia coli CFT073, complete genomeUnknown protein encoded within prophage2e-81300
NC_009800:289000:305342305342305782441Escherichia coli HS, complete genomeputative ninB protein2e-81300
NC_007946:1239278:125369712536971254137441Escherichia coli UTI89, complete genomeputative NinB protein encoded within prophage2e-81300
NC_011742:1177946:119458811945881195046459Escherichia coli S88 chromosome, complete genomerecombination protein ninB from phage origin2e-81300
NC_011601:717072:735071735071735511441Escherichia coli O127:H6 str. E2348/69 chromosome, complete genomeprotein NinB3e-81299
NC_011601:2614691:261575026157502616190441Escherichia coli O127:H6 str. E2348/69 chromosome, complete genomeprotein NinB1e-80298
NC_012759:4132527:414624541462454146685441Escherichia coli BW2952 chromosome, complete genomeProtein ninB1e-80298
NC_011751:1405381:142258614225861423044459Escherichia coli UMN026 chromosome, complete genomerecombination protein ninB from phage origin8e-81298
NC_007946:2625461:262598426259842626424441Escherichia coli UTI89, complete genomehypothetical protein6e-81298
NC_011205:609464:631320631320631778459Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853ninB protein1e-79294
NC_016860:364981:383394383394383831438Salmonella enterica subsp. enterica serovar Typhimurium strrecombination protein ninB from phage origin6e-78288
NC_014306:3524980:356371235637123564143432Erwinia billingiae Eb661, complete genomephage NinB protein2e-38157
NC_008570:2216736:224629022462902246730441Aeromonas hydrophila subsp. hydrophila ATCC 7966, complete genomeNinB protein2e-35147
NC_015663:4767443:477606547760654776514450Enterobacter aerogenes KCTC 2190 chromosome, complete genomeNinB family protein1e-25115
NC_015663:4522109:453126145312614531710450Enterobacter aerogenes KCTC 2190 chromosome, complete genomeNinB family protein1e-24111
NC_013364:1183000:119837811983781198911534Escherichia coli O111:H- str. 11128, complete genomehypothetical protein6e-24109
NC_013361:1558423:157471215747121575245534Escherichia coli O26:H11 str. 11368 chromosome, complete genomehypothetical protein6e-24109
NC_013361:3112023:312648431264843126930447Escherichia coli O26:H11 str. 11368 chromosome, complete genomehypothetical protein7e-24109
NC_011601:1039500:105553310555331055979447Escherichia coli O127:H6 str. E2348/69 chromosome, complete genomeprotein NinB1e-23108
NC_002655:1332961:134720813472081347654447Escherichia coli O157:H7 EDL933, complete genomeunknown protein encoded by bacteriophage BP-933W1e-23108
NC_013364:2645438:264744426474442647890447Escherichia coli O111:H- str. 11128, complete genomehypothetical protein2e-23107
NC_011147:2496808:250771325077132508159447Salmonella enterica subsp. enterica serovar Paratyphi A strhypothetical protein5e-23106
NC_006511:2501500:251217725121772512623447Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCChypothetical protein5e-23106
NC_013008:3231414:323272432327243233140417Escherichia coli O157:H7 str. TW14359 chromosome, complete genomeNinB protein1e-21102
NC_014121:3627588:366413436641343664544411Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, completeputative ninB protein7e-1889.4
NC_011740:2072173:210537121053712105787417Escherichia fergusonii ATCC 35469, complete genomeputative ninB protein6e-1889.4
NC_013361:3287671:329048132904813290891411Escherichia coli O26:H11 str. 11368 chromosome, complete genomerecombination protein1e-1788.2
NC_009778:2993218:301049330104933010903411Enterobacter sakazakii ATCC BAA-894, complete genomehypothetical protein2e-1787.4
NC_013282:1200993:122082112208211221231411Cronobacter turicensis, complete genomehypothetical protein6e-1682.8
NC_009567:904922:908461908461908877417Haemophilus influenzae PittGG chromosome, complete genomehypothetical protein1e-1478.6
NC_014922:825396:845110845110845526417Haemophilus influenzae F3047 chromosome, complete genomerecombination protein NinB1e-1478.6
NC_002927:2338549:234788923478892348296408Bordetella bronchiseptica RB50, complete genomehypothetical protein3e-1373.9
NC_011283:4212000:421354542135454214012468Klebsiella pneumoniae 342 chromosome, complete genomeninB protein1e-1271.6
NC_007712:1219957:124413012441301244570441Sodalis glossinidius str. 'morsitans', complete genomehypothetical protein1e-0858.9
NC_007712:2028500:207215420721542072591438Sodalis glossinidius str. 'morsitans', complete genomehypothetical protein2e-0857.4
NC_007712:1516589:153669315366931537130438Sodalis glossinidius str. 'morsitans', complete genomehypothetical protein2e-0857.4
NC_007712:3382000:338707633870763387489414Sodalis glossinidius str. 'morsitans', complete genomehypothetical protein2e-0754.7
NC_007712:1893066:190422519042251904638414Sodalis glossinidius str. 'morsitans', complete genomehypothetical protein2e-0754.7
NC_010682:2422500:243107024310702431495426Ralstonia pickettii 12J chromosome 1, complete sequencehypothetical protein2e-0650.8
NC_010002:3509506:353972835397283540126399Delftia acidovorans SPH-1, complete genomehypothetical protein7e-0649.3