Pre_GI: BLASTP Hits

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Query: NC_017328:303987:317642 Shigella flexneri 2002017 chromosome, complete genome

Start: 317642, End: 318337, Length: 696

Host Lineage: Shigella flexneri; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This organism, along with Shigella sonnei, is the major cause of shigellosis in industrialized countries and is responsible for endemic infections. This genus is named for the Japanese scientist (Shiga) who discovered them in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. Human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, and over 1 million deaths worldwide are attributed to them. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. Extremely virulent organisms that require very few cells in order to cause disease. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_002695:301939:301939301939302652714Escherichia coli O157:H7 str. Sakai, complete genomecI1e-81302
NC_013941:975353:989229989229989882654Escherichia coli O55:H7 str. CB9615 chromosome, complete genomeCI protein5e-123439
NC_012660:3116500:312771631277163128423708Pseudomonas fluorescens SBW25 chromosome, complete genomee14 prophage; putative phage repressor1e-29129
NC_000913:1188999:120148212014821202156675Escherichia coli K12, complete genomee14 prophage; repressor protein phage e142e-0755.8
NC_015566:3659318:366239936623993662980582Serratia sp. AS12 chromosome, complete genomehelix-turn-helix domain-containing protein2e-0859.7
NC_021066:2226826:224423422442342244866633Raoultella ornithinolytica B6, complete genomehypothetical protein7e-1580.9
NC_016809:1778000:177820117782011778866666Haemophilus influenzae 10810, complete genomehypothetical protein2e-1375.9
NC_016809:389561:394152394152394811660Haemophilus influenzae 10810, complete genomehypothetical protein1e-0859.7
NC_013941:3182576:319016231901623190836675Escherichia coli O55:H7 str. CB9615 chromosome, complete genomehypothetical protein3e-1168.9
NC_009783:1956000:195674419567441957409666Vibrio harveyi ATCC BAA-1116 chromosome I, complete sequencehypothetical protein2e-44179
NC_009778:2993218:301640330164033017065663Enterobacter sakazakii ATCC BAA-894, complete genomehypothetical protein2e-46185
NC_011083:374000:385883385883386533651Salmonella enterica subsp. enterica serovar Heidelberg str. SL476,P22 repressor protein c22e-31135
NC_009800:289000:301440301440302090651Escherichia coli HS, complete genomeP22 repressor protein c24e-31134
NC_013941:3300000:330265133026513303301651Escherichia coli O55:H7 str. CB9615 chromosome, complete genomeP22 repressor protein c24e-31134
NC_015663:4767443:478544147854414786193753Enterobacter aerogenes KCTC 2190 chromosome, complete genomeP22 repressor protein c22e-25115
NC_010002:2110953:212346721234672124114648Delftia acidovorans SPH-1, complete genomepeptidase S24 and S26 domain protein2e-1685.9
NC_004129:2201780:221380922138092214522714Pseudomonas fluorescens Pf-5, complete genomepeptidase S24-like domain3e-1479
NC_016830:5031819:504224950422495042896648Pseudomonas fluorescens F113 chromosome, complete genomepeptidase s24-like domain protein9e-1167
NC_014910:1708045:172518017251801725950771Alicycliphilus denitrificans BC chromosome, complete genomepeptidase s24/s26a/s26b, conserved region protein1e-1893.2
NC_007712:2028500:206857220685722069294723Sodalis glossinidius str. 'morsitans', complete genomephage repressor9e-61233
NC_010554:2646806:265134526513452651992648Proteus mirabilis HI4320, complete genomephage repressor1e-23110
NC_015424:2726223:275560227556022756036435Aeromonas veronii B565 chromosome, complete genomephage repressor7e-1064.3
NC_009348:1663870:166905016690501669733684Aeromonas salmonicida subsp. salmonicida A449, complete genomephage repressor7e-1580.9
NC_015968:3301958:331235333123533313006654Enterobacter asburiae LF7a chromosome, complete genomephage repressor like XRE family transcriptional regulator4e-21101
NC_011283:4212000:422109942210994221815717Klebsiella pneumoniae 342 chromosome, complete genomephage repressor protein6e-28124
NC_013361:3112023:312984531298453130495651Escherichia coli O26:H11 str. 11368 chromosome, complete genomephage repressor protein CI4e-31134
NC_011353:305820:305820305820306533714Escherichia coli O157:H7 str. EC4115 chromosome, complete genomeprophage repressor1e-81302
NC_008563:1175035:118767011876701188365696Escherichia coli APEC O1, complete genomeputative CI repressor of bacteriophage4e-131467
NC_007946:1239278:125028212502821250935654Escherichia coli UTI89, complete genomeputative CI repressor of bacteriophage5e-123439
NC_002655:301940:301940301940302653714Escherichia coli O157:H7 EDL933, complete genomeputative cI repressor protein for prophage CP-933H1e-81302
NC_015379:4691868:469213346921334692831699Pseudomonas brassicacearum subsp. brassicacearum NFM421 chromosome,Putative phage regulatory protein2e-23109
NC_011415:2153243:216098621609862161642657Escherichia coli SE11 chromosome, complete genomeputative phage repressor1e-26119
NC_007946:2931364:293500329350032935677675Escherichia coli UTI89, complete genomeputative phage repressor2e-0755.8
NC_013799:502126:507005507005507667663Hydrogenobacter thermophilus TK-6, complete genomeputative phage repressor2e-0653.1
NC_008563:2946391:295003029500302950704675Escherichia coli APEC O1, complete genomeputative phage repressor2e-0755.8
NC_017161:502206:506995506995507657663Hydrogenobacter thermophilus TK-6 chromosome, complete genomeputative phage repressor2e-0653.1
NC_013364:2645438:265235726523572652980624Escherichia coli O111:H- str. 11128, complete genomeputative phage repressor protein CI1e-120432
NC_009524:1627414:163576016357601636419660Psychrobacter sp. PRwf-1 chromosome, complete genomeputative prophage repressor6e-1271.2
NC_013446:3034486:304282630428263043365540Comamonas testosteroni CNB-2, complete genomeputative prophage repressor2e-1273.2
NC_007794:3218729:322968332296833230366684Novosphingobium aromaticivorans DSM 12444, complete genomeputative prophage repressor2e-0962.8
NC_008258:269806:287337287337287969633Shigella flexneri 5 str. 8401, complete genomeputative prophage repressor CI1e-22106
NC_012731:2083650:209731020973102098035726Klebsiella pneumoniae NTUH-K2044 chromosome, complete genomeputative repressor protein of prophage2e-21102
NC_004431:3040953:305923330592333059859627Escherichia coli CFT073, complete genomePutative repressor protein of prophage3e-25115
NC_017047:1906000:190737719073771908024648Rahnella aquatilis HX2 chromosome, complete genomeputative repressor protein of prophage9e-1580.5
NC_002947:3404000:341945034194503420181732Pseudomonas putida KT2440, complete genomepyocin R2_PP, transcriptional repressor, CI/C2 family7e-21100
NC_011601:1039500:105177110517711052424654Escherichia coli O127:H6 str. E2348/69 chromosome, complete genomerepressor protein5e-123439
NC_004431:1401681:141242714124271412849423Escherichia coli CFT073, complete genomeRepressor protein9e-74276
NC_011601:2614691:261961826196182620331714Escherichia coli O127:H6 str. E2348/69 chromosome, complete genomerepressor protein5e-83307
NC_007946:2625461:262998526299852630635651Escherichia coli UTI89, complete genomerepressor protein9e-31133
NC_004578:3849835:385799038579903858721732Pseudomonas syringae pv. tomato str. DC3000, complete genomerepressor protein c21e-21103
NC_009708:2537557:255467625546762555386711Yersinia pseudotuberculosis IP 31758 chromosome, complete genomerepressor protein C24e-1685.1
NC_014640:4293430:433149743314974332201705Achromobacter xylosoxidans A8 chromosome, complete genomerepressor protein C2 domain-containing protein3e-1168.6
NC_012779:2184927:220196422019642202635672Edwardsiella ictaluri 93-146, complete genomerepressor protein CI1e-47189
NC_004578:4499143:452278245227824523486705Pseudomonas syringae pv. tomato str. DC3000, complete genomerepressor protein cI4e-2098.2
NC_014306:3524980:356790335679033568601699Erwinia billingiae Eb661, complete genomeRepressor protein cI3e-49194
NC_012759:4132527:414282841428284143541714Escherichia coli BW2952 chromosome, complete genomeRepressor protein CI7e-83306
NC_017986:4091051:410215841021584102514357Pseudomonas putida ND6 chromosome, complete genomerepressor protein CI2e-0859.3
NC_020418:3133831:313802131380213138731711Morganella morganii subsp. morganii KT, complete genomerepressor protein CI1e-54213
NC_011742:1177946:119125811912581191959702Escherichia coli S88 chromosome, complete genomeRepressor protein CI from phage origin6e-131466
AC_000091:1191353:120383612038361204510675Escherichia coli W3110 DNA, complete genomerepressor protein phage e142e-0755.8
NC_011750:5045927:505908250590825059756675Escherichia coli IAI39 chromosome, complete genomerepressor protein phage e14; e14 prophage2e-0756.2
NC_011742:2863316:286734128673412868015675Escherichia coli S88 chromosome, complete genomerepressor protein phage e14; e14 prophage2e-0755.8
NC_006138:2288261:230836023083602309070711Desulfotalea psychrophila LSv54, complete genomesimilar to repressor protein5e-1064.7
NC_007645:605500:605820605820606407588Hahella chejuensis KCTC 2396, complete genomeSOS-response transcriptional repressors (RecA-mediated autopeptidase)3e-0962.4
NC_020418:2910593:291496229149622915621660Morganella morganii subsp. morganii KT, complete genomeSOS-response transcriptional repressors (RecA-mediated autopeptidases)2e-23109
NC_015389:905165:918044918044918676633Coriobacterium glomerans PW2 chromosome, complete genometranscriptional regulator, XRE family1e-0963.5
NC_012791:2832001:285731328573132857981669Variovorax paradoxus S110 chromosome 1, complete genometranscriptional regulator, XRE family6e-0961.2
NC_013850:1887556:189996518999651900627663Klebsiella variicola At-22 chromosome, complete genometranscriptional regulator, XRE family1e-49196
NC_017986:5509569:552387155238715524602732Pseudomonas putida ND6 chromosome, complete genometranscriptional repressor pyocin R2 PP3e-21102
NC_011146:1998981:202611320261132026718606Geobacter bemidjiensis Bem, complete genometranscriptional repressor, LexA family1e-0756.6
NC_014837:2354241:235780423578042358529726Pantoea sp. At-9b chromosome, complete genomeXRE family transcriptional regulator6e-44177
NC_012947:3015985:302163430216343022284651Escherichia coli 'BL21-Gold(DE3)pLysS AG' chromosome, completeXRE family transcriptional regulator4e-31134
NC_017294:115500:117859117859118473615Candidatus Arthromitus sp. SFB-mouse-Yit, complete genomeXRE family transcriptional regulator7e-0754.3