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Query: NC_017328:303987:312617 Shigella flexneri 2002017 chromosome, complete genome

Start: 312617, End: 313291, Length: 675

Host Lineage: Shigella flexneri; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This organism, along with Shigella sonnei, is the major cause of shigellosis in industrialized countries and is responsible for endemic infections. This genus is named for the Japanese scientist (Shiga) who discovered them in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. Human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, and over 1 million deaths worldwide are attributed to them. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. Extremely virulent organisms that require very few cells in order to cause disease. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009800:289000:293833293833294474642Escherichia coli HS, complete genomehypothetical protein3e-36151
NC_008258:269806:279662279662280501840Shigella flexneri 5 str. 8401, complete genomeputative bacteriophage protein7e-34144
NC_013364:2645438:265798926579892658792804Escherichia coli O111:H- str. 11128, complete genomehypothetical protein1e-1686.7
NC_013364:1183000:118610011861001187095996Escherichia coli O111:H- str. 11128, complete genomehypothetical protein3e-1685.5
NC_006905:368942:3749463749463761211176Salmonella enterica subsp. enterica serovar Choleraesuis strEaa protein4e-1065.1
AP010958:5361207:536761653676165367996381Escherichia coli O103:H2 str. 12009 DNA, complete genomehypothetical protein3e-0962
NC_013353:5361207:536761653676165367996381Escherichia coli O103:H2 str. 12009, complete genomehypothetical protein3e-0962
NC_013361:1558423:156185315618531562764912Escherichia coli O26:H11 str. 11368 chromosome, complete genomehypothetical protein3e-0962
NC_013364:1596278:161111016111101611463354Escherichia coli O111:H- str. 11128, complete genomehypothetical protein4e-0961.6
NC_002655:1332961:133323813332381333861624Escherichia coli O157:H7 EDL933, complete genomeunknown protein encoded by bacteriophage BP-933W7e-0960.8
NC_013008:3231414:324675732467573247374618Escherichia coli O157:H7 str. TW14359 chromosome, complete genomehypothetical protein7e-0960.8
NC_011353:3276734:329188632918863292503618Escherichia coli O157:H7 str. EC4115 chromosome, complete genome7e-0960.8
NC_010067:2304313:232186323218632322444582Salmonella enterica subsp. arizonae serovar 62:z4,z23:--, completehypothetical protein2e-0859.7
NC_011205:609464:6195466195466206281083Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853Eaa protein2e-0859.7
NC_011083:374000:379255379255379941687Salmonella enterica subsp. enterica serovar Heidelberg str. SL476,Eaa protein6e-0857.8
NC_011294:2053991:205626120562612057124864Salmonella enterica subsp. enterica serovar Enteritidis strphage protein7e-0857.4
NC_011094:593100:602303602303602980678Salmonella enterica subsp. enterica serovar Schwarzengrund strvalyl-tRNA synthetase1e-0756.6
NC_016860:364981:371050371050371841792Salmonella enterica subsp. enterica serovar Typhimurium strhypothetical protein9e-0753.9
NC_007946:2625461:263614426361442636716573Escherichia coli UTI89, complete genomehypothetical protein1e-0653.5
AP010958:2911741:291747429174742918427954Escherichia coli O103:H2 str. 12009 DNA, complete genomehypothetical protein1e-0653.5
NC_013353:2911741:291747429174742918427954Escherichia coli O103:H2 str. 12009, complete genomehypothetical protein1e-0653.5
NC_013361:3651150:365492736549273655790864Escherichia coli O26:H11 str. 11368 chromosome, complete genomehypothetical protein2e-0652.8
NC_011601:717072:722714722714723346633Escherichia coli O127:H6 str. E2348/69 chromosome, complete genomehypothetical protein9e-0650.4
NC_011601:2614691:262858426285842629216633Escherichia coli O127:H6 str. E2348/69 chromosome, complete genomehypothetical protein9e-0650.4