Pre_GI: BLASTP Hits

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Query: NC_017328:303987:308963 Shigella flexneri 2002017 chromosome, complete genome

Start: 308963, End: 310216, Length: 1254

Host Lineage: Shigella flexneri; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This organism, along with Shigella sonnei, is the major cause of shigellosis in industrialized countries and is responsible for endemic infections. This genus is named for the Japanese scientist (Shiga) who discovered them in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. Human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, and over 1 million deaths worldwide are attributed to them. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. Extremely virulent organisms that require very few cells in order to cause disease. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_004337:309833:3098333098333110861254Shigella flexneri 2a str. 301, complete genomegamma-glutamyl phosphate reductase0847
NC_004741:310382:3123853123853136381254Shigella flexneri 2a str. 2457T, complete genomegamma-glutamyl phosphate reductase0847
NC_007946:289425:2936972936972949501254Escherichia coli UTI89, complete genomegamma-glutamyl phosphate reductase0843
NC_008563:287136:2936762936762949291254Escherichia coli APEC O1, complete genomegamma-glutamyl phosphate reductase0843
NC_011742:291237:2936962936962949491254Escherichia coli S88 chromosome, complete genomegamma-glutamyl phosphate reductase0843
NC_007384:307013:3134813134813147341254Shigella sonnei Ss046, complete genomegamma-glutamylphosphate reductase0843
NC_010498:301000:3052713052713065241254Escherichia coli SMS-3-5, complete genomegamma-glutamyl phosphate reductase0842
NC_011745:291422:2956232956232968761254Escherichia coli ED1a chromosome, complete genomegamma-glutamyl phosphate reductase0840
NC_004431:364000:3688563688563701091254Escherichia coli CFT073, complete genomegamma-glutamyl phosphate reductase0840
NC_009800:289000:2903732903732916261254Escherichia coli HS, complete genomegamma-glutamyl phosphate reductase0839
NC_013361:313540:3200083200083212611254Escherichia coli O26:H11 str. 11368 chromosome, complete genomegamma-glutamyl phosphate reductase0839
NC_020063:3690308:3741867374186737431201254Enterobacteriaceae bacterium strain FGI 57, complete genomeglutamate-5-semialdehyde dehydrogenase0747
NC_014121:1101093:1106436110643611076891254Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, completegamma-glutamyl phosphate reductase0746
NC_014618:3700640:3712514371251437137671254Enterobacter cloacae SCF1 chromosome, complete genomegamma-glutamyl phosphate reductase0746
NC_011283:4438500:4443738444373844449911254Klebsiella pneumoniae 342 chromosome, complete genomegamma-glutamyl phosphate reductase0744
NC_009648:293052:3173203173203185731254Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genomegamma-glutamyl phosphate reductase0744
NC_016514:891772:8983428983428995951254Enterobacter cloacae EcWSU1 chromosome, complete genomegamma-glutamyl phosphate reductase0743
NC_012731:1088321:1102356110235611036091254Klebsiella pneumoniae NTUH-K2044 chromosome, complete genomegamma-glutamyl phosphate reductase0743
NC_021066:3028421:3033407303340730346601254Raoultella ornithinolytica B6, complete genomegamma-glutamyl phosphate reductase0734
NC_006905:368942:3713913713913726411251Salmonella enterica subsp. enterica serovar Choleraesuis strgamma-glutamyl phosphate reductase0729
NC_011083:374000:3753943753943766441251Salmonella enterica subsp. enterica serovar Heidelberg str. SL476,glutamate-5-semialdehyde dehydrogenase0728
NC_003197:367430:3674303674303686801251Salmonella typhimurium LT2, complete genomegamma-glutamyl phosphate reductase0727
NC_016810:366908:3669083669083681581251Salmonella enterica subsp. enterica serovar Typhimurium strgamma-glutamyl phosphate reductase0727
NC_016856:365665:3681153681153693651251Salmonella enterica subsp. enterica serovar Typhimurium str. 14028Sgamma-glutamyl phosphate reductase0727
NC_016857:366908:3669083669083681581251Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74gamma-glutamyl phosphate reductase0727
NC_016860:364981:3674313674313686811251Salmonella enterica subsp. enterica serovar Typhimurium strgamma-glutamyl phosphate reductase0727
NC_016863:367404:3674043674043686541251Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1gamma-glutamyl phosphate reductase0727
NC_017046:366905:3669053669053681551251Salmonella enterica subsp. enterica serovar Typhimurium str. 798gamma-glutamyl phosphate reductase0727
NC_016832:2581145:2600031260003126012811251Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12,Gamma-glutamyl phosphate reductase0726
NC_004631:2584244:2603130260313026043801251Salmonella enterica subsp. enterica serovar Typhi Ty2, completegamma-glutamyl phosphate reductase0726
NC_015761:299386:3031903031903044401251Salmonella bongori NCTC 12419, complete genomegamma-glutamyl phosphate reductase0724
NC_011294:346915:3469153469153481621248Salmonella enterica subsp. enterica serovar Enteritidis strgamma-glutamyl phosphate reductase0723
NC_011205:371001:3710013710013722481248Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853gamma-glutamyl phosphate reductase0723
NC_013716:357928:3621343621343633841251Citrobacter rodentium ICC168, complete genomegamma-glutamyl phosphate reductase0719
NC_020260:3004500:3016421301642130176741254Cronobacter sakazakii Sp291, complete genomegamma-glutamyl phosphate reductase0700
NC_013282:923500:9285639285639298161254Cronobacter turicensis, complete genomeGamma-glutamyl phosphate reductase0694
NC_014500:3744705:3765049376504937663021254Dickeya dadantii 3937 chromosome, complete genomegamma-glutamylphosphate reductase0664
NC_004547:3866439:3881462388146238827151254Erwinia carotovora subsp. atroseptica SCRI1043, complete genomegamma-glutamyl phosphate reductase0641
NC_020211:996497:1001998100199810032511254Serratia marcescens WW4, complete genomegamma-glutamylphosphate reductase0641
NC_013508:876431:8819678819678832201254Edwardsiella tarda EIB202, complete genomegamma-glutamyl phosphate reductase2e-179628
NC_013421:3752619:3767431376743137686841254Pectobacterium wasabiae WPP163, complete genomegamma-glutamyl phosphate reductase6e-179627
NC_012917:3684840:3697827369782736990801254Pectobacterium carotovorum subsp. carotovorum PC1, complete genomegamma-glutamyl phosphate reductase7e-179626
NC_010634:1056441:1074550107455010758091260Yersinia pseudotuberculosis PB1/+, complete genomegamma-glutamyl phosphate reductase6e-177620
NC_006155:1074298:1092407109240710936661260Yersinia pseudotuberculosis IP 32953, complete genomegamma-glutamyl phosphate reductase6e-177620
NC_010465:3597000:3597278359727835985371260Yersinia pseudotuberculosis YPIII, complete genomegamma-glutamyl phosphate reductase6e-177620
NC_009708:3542336:3543422354342235446811260Yersinia pseudotuberculosis IP 31758 chromosome, complete genomegamma-glutamyl phosphate reductase6e-177620
NC_005810:754340:7725057725057737641260Yersinia pestis biovar Microtus str. 91001, complete genomegamma-glutamyl phosphate reductase1e-176619
NC_004088:1075454:1092769109276910940281260Yersinia pestis KIM, complete genomegamma-glutamyl phosphate reductase1e-176619
NC_008150:3015000:3016232301623230174911260Yersinia pestis Antiqua, complete genomegamma-glutamyl phosphate reductase1e-176619
NC_010159:3502350:3503436350343635046951260Yersinia pestis Angola, complete genomegamma-glutamyl phosphate reductase1e-176619
NC_008149:1002453:1019768101976810210271260Yersinia pestis Nepal516, complete genomegamma-glutamyl phosphate reductase1e-176619
NC_003143:3583468:3584554358455435858131260Yersinia pestis CO92, complete genomegamma-glutamyl phosphate reductase1e-176619
NC_009381:3228500:3228818322881832300771260Yersinia pestis Pestoides F chromosome, complete genomegamma-glutamyl phosphate reductase1e-176619
NC_017265:3375463:3376184337618433774431260Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,gamma-glutamylphosphate reductase1e-176619
NC_017168:2158839:2176154217615421774131260Yersinia pestis A1122 chromosome, complete genomegamma-glutamyl phosphate reductase1e-176619
NC_017160:3560153:3561239356123935624981260Yersinia pestis D182038 chromosome, complete genomegamma-glutamyl phosphate reductase1e-176619
NC_017154:3576256:3577342357734235786011260Yersinia pestis D106004 chromosome, complete genomegamma-glutamyl phosphate reductase1e-176619
NC_014029:3633955:3635041363504136363001260Yersinia pestis Z176003 chromosome, complete genomegamma-glutamyl phosphate reductase1e-176619
NC_012779:916000:9174509174509185201071Edwardsiella ictaluri 93-146, complete genomeglutamate-5-semialdehyde dehydrogenase, putative8e-159560
NC_016513:54802:6829968299694381140Aggregatibacter actinomycetemcomitans ANH9381 chromosome, completegamma-glutamyl phosphate reductase2e-144512
NC_014314:238043:2823482823482836191272Dehalogenimonas lykanthroporepellens BL-DC-9 chromosome, completegamma-glutamyl phosphate reductase8e-124443
NC_016751:2044379:2062412206241220636561245Marinitoga piezophila KA3 chromosome, complete genomegamma-glutamyl phosphate reductase3e-123441
NC_018664:1279950:1286848128684812880951248Clostridium acidurici 9a chromosome, complete genomegamma-glutamyl phosphate reductase ProA3e-112405
NC_010483:642577:6532356532356544821248Thermotoga sp. RQ2, complete genomegamma-glutamyl phosphate reductase7e-112404
NC_013642:942767:9660019660019672481248Thermotoga naphthophila RKU-10, complete genomegamma-glutamyl phosphate reductase1e-111403
NC_010999:2483000:2496204249620424974601257Lactobacillus casei, complete genomeGamma-glutamyl phosphate reductase (GPR) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase) (GSA dehydrogenase)4e-110398
NC_004070:1409714:1408471140847114097211251Streptococcus pyogenes MGAS315, complete genomegamma-glutamyl phosphate reductase3e-109395
NC_004606:470667:4871644871644884141251Streptococcus pyogenes SSI-1, complete genomegamma-glutamyl phosphate reductase3e-109395
NC_013199:2386924:2403606240360624048621257Lactobacillus rhamnosus Lc 705, complete genomegamma-glutamyl phosphate reductase (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialdehyde dehydrogenase) (GSA dehydrogenase)1e-107390
NC_015873:2260048:2280960228096022822041245Megasphaera elsdenii DSM 20460, complete genomegamma-glutamyl phosphate reductase2e-107389
NC_011979:646518:6742636742636755191257Geobacter sp. FRC-32, complete genomegamma-glutamyl phosphate reductase2e-106386
NC_015588:2200517:2221613222161322229291317Isoptericola variabilis 225 chromosome, complete genomeGamma-glutamyl phosphate reductase3e-106385
NC_014650:1410790:1432142143214214333831242Geobacillus sp. Y4.1MC1 chromosome, complete genomegamma-glutamyl phosphate reductase6e-103374
NC_015499:1403447:1408165140816514094301266Thermodesulfobium narugense DSM 14796 chromosome, complete genomeGamma-glutamyl phosphate reductase5e-102371
NC_013205:2922343:2947213294721329484991287Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446,gamma-glutamyl phosphate reductase1e-99363
NC_016584:3645245:3650810365081036520571248Desulfosporosinus orientis DSM 765 chromosome, complete genomegamma-glutamyl phosphate reductase5e-99361
NC_014323:625155:6495836495836508511269Herbaspirillum seropedicae SmR1 chromosome, complete genomegamma-glutamyl phosphate reductase7e-99360
NC_021175:751616:7516167516167528781263Streptococcus oligofermentans AS 1.3089, complete genomegamma-glutamyl phosphate reductase2e-98359
NC_013851:2441407:2454628245462824559021275Allochromatium vinosum DSM 180 chromosome, complete genomegamma-glutamyl phosphate reductase2e-96352
NC_015557:583475:6060396060396073641326Hydrogenobaculum sp. 3684 chromosome, complete genomegamma-glutamyl phosphate reductase1e-93343
NC_020411:583503:6060676060676073921326Hydrogenobaculum sp. HO, complete genomeglutamate-5-semialdehyde dehydrogenase1e-93343
NC_015587:583530:6060946060946074191326Hydrogenobaculum sp. SHO chromosome, complete genomeGamma-glutamyl phosphate reductase1e-93343
NC_005125:4117096:4117096411709641183551260Gloeobacter violaceus PCC 7421, complete genomegamma-glutamyl phosphate reductase3e-93342
NC_009654:3215205:3227847322784732291061260Marinomonas sp. MWYL1, complete genomegamma-glutamyl phosphate reductase1e-92340
NC_009429:686608:7027847027847040461263Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, completegamma-glutamyl phosphate reductase6e-92338
NC_012803:1094679:1094679109467910960281350Micrococcus luteus NCTC 2665, complete genomeglutamate-5-semialdehyde dehydrogenase9e-91334
NC_005956:196976:2214442214442226821239Bartonella henselae str. Houston-1, complete genomeGamma-glutamyl phosphate reductase1e-90333
NC_009665:5072413:5113207511320751144541248Shewanella baltica OS185 chromosome, complete genomegamma-glutamyl phosphate reductase2e-90332
NC_005955:173436:1962621962621975001239Bartonella quintana str. Toulouse, complete genomeGamma-glutamyl phosphate reductase3e-90332
NC_011883:519308:5328745328745341451272Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774,gamma-glutamyl phosphate reductase8e-90330
NC_020301:174467:2031642031642044201257Bartonella vinsonii subsp. berkhoffii str. Winnie, complete genomegamma-glutamyl phosphate reductase1e-89330
NC_018876:1121268:1140105114010511414601356Methanolobus psychrophilus R15 chromosome, complete genomegamma-glutamyl phosphate reductase3e-89329
NC_016627:1213357:1217171121717112184661296Clostridium clariflavum DSM 19732 chromosome, complete genomeglutamate-5-semialdehyde dehydrogenase1e-88327
NC_015593:2103815:2142420214242021437211302Sphingobium chlorophenolicum L-1 chromosome chromosome 1, completeGamma-glutamyl phosphate reductase2e-88326
NC_014623:2283253:2301701230170123029691269Stigmatella aurantiaca DW4/3-1 chromosome, complete genomegamma-glutamyl phosphate reductase3e-88325
NC_010162:5129270:5145158514515851464381281Sorangium cellulosum 'So ce 56', complete genomehypothetical protein1e-87323
NC_019977:1996414:2014069201406920154301362Methanomethylovorans hollandica DSM 15978, complete genomegamma-glutamyl phosphate reductase3e-87322
NC_014923:1249267:1269522126952212708081287Mesorhizobium ciceri biovar biserrulae WSM1271 chromosome, completegamma-glutamyl phosphate reductase4e-87322
NC_007955:2531751:2542356254235625437051350Methanococcoides burtonii DSM 6242, complete genomegamma-glutamyl phosphate reductase5e-87322
NC_007514:1475323:1489710148971014909661257Chlorobium chlorochromatii CaD3, complete genomegamma-glutamyl phosphate reductase2e-86320
NC_014253:795869:8150308150308163761347Methanohalobium evestigatum Z-7303 chromosome, complete genomegamma-glutamyl phosphate reductase2e-86320
NC_010161:205500:2291572291572304131257Bartonella tribocorum CIP 105476, complete genomehypothetical protein2e-86320
NC_014002:631649:6363876363876377301344Methanohalophilus mahii DSM 5219 chromosome, complete genomeglutamate-5-semialdehyde dehydrogenase1e-86320
NC_014932:1232346:1233955123395512352231269Bartonella clarridgeiae 73, complete genomeGamma-glutamyl phosphate reductase1e-85317
NC_016894:3114394:3115855311585531171501296Acetobacterium woodii DSM 1030 chromosome, complete genomegamma-glutamyl phosphate reductase2e-85317
NC_003317:190975:2143162143162155961281Brucella melitensis 16M chromosome I, complete sequencegamma-glutamyl phosphate reductase3e-85315
NC_011884:4366831:4369073436907343703741302Cyanothece sp. PCC 7425, complete genomegamma-glutamyl phosphate reductase1e-84313
NC_008380:4968492:4986092498609249873751284Rhizobium leguminosarum bv. viciae 3841, complete genomeputative gamma-glutamyl phosphate reductase5e-84311
NC_003047:3419212:3443374344337434446571284Sinorhizobium meliloti 1021, complete genomegamma-glutamyl phosphate reductase6e-84311
NC_006677:1255079:1256139125613912574221284Gluconobacter oxydans 621H, complete genomeGamma-glutamyl phosphate reductase1e-83310
NC_009337:1448607:1448607144860714498751269Chlorobium phaeovibrioides DSM 265 chromosome, complete genomegamma-glutamyl phosphate reductase8e-83307
NC_009614:769851:7822917822917835441254Bacteroides vulgatus ATCC 8482 chromosome, complete genomegamma-glutamyl phosphate reductase3e-81302
NC_016078:3130573:3150912315091231521951284Pelagibacterium halotolerans B2 chromosome, complete genomegamma-glutamyl phosphate reductase6e-81301
NC_018644:137755:1720491720491733021254Alpha proteobacterium HIMB59 chromosome, complete genomeglutamate-5-semialdehyde dehydrogenase2e-78293
NC_011565:1054414:1055500105550010567591260Candidatus Azobacteroides pseudotrichonymphae genomovar. CFP2,glutamate-5-semialdehyde dehydrogenase1e-77290
NC_007205:221539:2236202236202248701251Candidatus Pelagibacter ubique HTCC1062, complete genomeGamma-glutamyl phosphate reductase1e-76287
NC_015167:724934:7249347249347261331200Cellulophaga lytica DSM 7489 chromosome, complete genomegamma-glutamyl phosphate reductase3e-66252
NC_015638:591964:5919645919645931661203Lacinutrix sp. 5H-3-7-4 chromosome, complete genomegamma-glutamyl phosphate reductase3e-65249
NC_016001:2421580:2427675242767524288711197Flavobacterium branchiophilum, complete genomeglutamate-5-semialdehyde dehydrogenase3e-64246
NC_013161:1801904:1825588182558818268501263Cyanothece sp. PCC 8802, complete genomeGlutamate-5-semialdehyde dehydrogenase9e-51201
NC_009922:868262:8777758777758792531479Alkaliphilus oremlandii OhILAs, complete genomeacetaldehyde dehydrogenase (acetylating)4e-0963.2
NC_016048:1580352:1593486159348615962572772Oscillibacter valericigenes Sjm18-20, complete genomeacetaldehyde dehydrogenase/alcohol dehydrogenase4e-0859.7
NC_010001:1745089:1764393176439317659401548Clostridium phytofermentans ISDg, complete genomeacetaldehyde dehydrogenase (acetylating)7e-0858.9
NC_014019:3543389:3552532355253235540611530Bacillus megaterium QM B1551 chromosome, complete genomeacetaldehyde dehydrogenase (acetylating)7e-0858.9
NC_008261:1048515:1060624106062410621021479Clostridium perfringens ATCC 13124, complete genomeethanolamine utilization protein1e-0758.2
NC_003366:1091766:1103887110388711053651479Clostridium perfringens str. 13, complete genomeprobable alcohol dehydrogenase1e-0758.2
NC_010723:1465097:1471942147194214734321491Clostridium botulinum E3 str. Alaska E43, complete genomealdehyde-alcohol dehydrogenase 22e-0757.4
NC_020419:870160:8730338730338756782646Uncultured Termite group 1 bacterium phylotype Rs-D17 DNA, completealdehyde-alcohol dehydrogenase4e-0756.6
NS_000191:870160:8730338730338756782646Uncultured Termite group 1 bacterium phylotype Rs-D17, completealdehyde-alcohol dehydrogenase4e-0756.6
NC_007930:180281:1914701914701941272658Lactobacillus salivarius subsp. salivarius UCC118 plasmid pMP118,Alcohol dehydrogenase / Acetaldehyde dehydrogenase6e-0755.5
NC_010674:1496500:1501729150172915032191491Clostridium botulinum B str. Eklund 17B, complete genomealdehyde-alcohol dehydrogenase 21e-0655.1
NC_009438:2058566:2058566205856620611782613Shewanella putrefaciens CN-32 chromosome, complete genomebifunctional acetaldehyde-CoA/alcohol dehydrogenase1e-0654.7
NC_017179:2067015:2078829207882920802981470Clostridium difficile BI1, complete genomeethanolamine/propanediol utilisation aldehyde-alcohol dehydrogenase1e-0654.7
NC_013315:2059007:2070821207082120722901470Clostridium difficile CD196 chromosome, complete genomeethanolamine/propanediol utilisation aldehyde-alcohol dehydrogenase1e-0654.7
NC_008697:118859:1482871482871496991413Nocardioides sp. JS614 plasmid pNOCA01, complete sequencesuccinate-semialdehyde dehydrogenase (NAD(P)(+))1e-0654.3
NC_011663:2813033:2829398282939828320012604Shewanella baltica OS223 chromosome, complete genomebifunctional acetaldehyde-CoA/alcohol dehydrogenase2e-0654.3
NC_008321:1993541:1993541199354119961412601Shewanella sp. MR-4, complete genomeiron-containing alcohol dehydrogenase2e-0654.3
NC_009633:286677:2984592984592999101452Alkaliphilus metalliredigens QYMF chromosome, complete genomeacetaldehyde dehydrogenase2e-0653.9
NC_007907:456164:4706654706654721521488Desulfitobacterium hafniense Y51, complete genomehypothetical protein2e-0653.9
NC_014376:1586649:1599258159925816007361479Clostridium saccharolyticum WM1 chromosome, complete genomeacetaldehyde dehydrogenase (acetylating)2e-0653.9
NC_010723:1465097:1483506148350614850651560Clostridium botulinum E3 str. Alaska E43, complete genomeacetaldehyde dehydrogenase (acetylating)5e-0652.8
NC_010674:1496500:1513293151329315148521560Clostridium botulinum B str. Eklund 17B, complete genomeacetaldehyde dehydrogenase (acetylating)5e-0652.8
NC_015275:4493500:4498841449884145003161476Clostridium lentocellum DSM 5427 chromosome, complete genomeacetaldehyde dehydrogenase (acetylating)5e-0652.8
NC_016584:1998000:2027333202733320288201488Desulfosporosinus orientis DSM 765 chromosome, complete genomeacetaldehyde dehydrogenase6e-0652.4
NC_009633:3933941:3941058394105839425841527Alkaliphilus metalliredigens QYMF chromosome, complete genomeacetaldehyde dehydrogenase6e-0652.4
NC_009253:1381401:1395243139524313966971455Desulfotomaculum reducens MI-1 chromosome, complete genomeacetaldehyde dehydrogenase6e-0652.4
NC_016584:1714507:1719592171959217210761485Desulfosporosinus orientis DSM 765 chromosome, complete genomeacetaldehyde dehydrogenase8e-0652