Pre_GI: BLASTP Hits

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Query: NC_017328:303987:305418 Shigella flexneri 2002017 chromosome, complete genome

Start: 305418, End: 305690, Length: 273

Host Lineage: Shigella flexneri; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This organism, along with Shigella sonnei, is the major cause of shigellosis in industrialized countries and is responsible for endemic infections. This genus is named for the Japanese scientist (Shiga) who discovered them in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. Human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, and over 1 million deaths worldwide are attributed to them. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. Extremely virulent organisms that require very few cells in order to cause disease. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_013361:313540:317110317110317511402Escherichia coli O26:H11 str. 11368 chromosome, complete genomeDNA-binding transcriptional regulator Crl1e-36151
NC_007384:307013:310583310583310984402Shigella sonnei Ss046, complete genometranscriptional regulator of cryptic csgA gene for curli surface fibers1e-36151
NC_010498:301000:302373302373302774402Escherichia coli SMS-3-5, complete genomesigma factor-binding protein Crl1e-35148
NC_004431:364000:365957365957366358402Escherichia coli CFT073, complete genomeCurlin genes transcriptional activatory protein2e-34144
NC_008563:287136:290706290706291107402Escherichia coli APEC O1, complete genomecrl transcriptional regulator2e-34144
NC_007946:289425:290727290727291128402Escherichia coli UTI89, complete genomecrl transcriptional regulator2e-34144
NC_011745:291422:292724292724293125402Escherichia coli ED1a chromosome, complete genomeDNA-binding transcriptional regulator Crl2e-34144
NC_013716:357928:359230359230359631402Citrobacter rodentium ICC168, complete genomesigma factor-binding protein crl (curlin genes transcriptional activator)3e-32137
NC_015761:299386:301235301235301636402Salmonella bongori NCTC 12419, complete genomecurlin genes transcriptional activator7e-31132
NC_016514:891772:895332895332895757426Enterobacter cloacae EcWSU1 chromosome, complete genomeSigma factor-binding protein crl5e-26116
NC_020211:996497:100036710003671000768402Serratia marcescens WW4, complete genomesigma factor-binding protein9e-25112
NC_020063:3690308:374573937457393746140402Enterobacteriaceae bacterium strain FGI 57, complete genomeTranscriptional regulator Crl8e-25112
NC_014618:3700640:371637437163743716775402Enterobacter cloacae SCF1 chromosome, complete genometranscriptional regulator Crl2e-24111
NC_014121:1101093:110244311024431102754312Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, completehypothetical protein2e-22103
NC_020260:3004500:302027230202723020661390Cronobacter sakazakii Sp291, complete genomeDNA-binding transcriptional regulator Crl1e-21102
NC_010634:1056441:107285910728591073260402Yersinia pseudotuberculosis PB1/+, complete genometranscriptional regulator Crl4e-2199.8
NC_010159:3502350:350598535059853506386402Yersinia pestis Angola, complete genometranscriptional activator Crl4e-2199.8
NC_005810:754340:770814770814771215402Yersinia pestis biovar Microtus str. 91001, complete genomeDNA-binding transcriptional regulator Crl4e-2199.8
NC_008149:1002453:101807710180771018478402Yersinia pestis Nepal516, complete genomecurlin genes regulatory protein4e-2199.8
NC_008150:3015000:301878130187813019182402Yersinia pestis Antiqua, complete genomecurlin genes regulatory protein4e-2199.8
NC_010465:3597000:359982735998273600228402Yersinia pseudotuberculosis YPIII, complete genometranscriptional regulator Crl4e-2199.8
NC_004088:1075454:109107810910781091479402Yersinia pestis KIM, complete genometranscriptional regulator of cryptic csgA gene for curli surface fibers4e-2199.8
NC_003143:3583468:358710335871033587504402Yersinia pestis CO92, complete genomecurlin genes regulatory protein4e-2199.8
NC_006155:1074298:109071610907161091117402Yersinia pseudotuberculosis IP 32953, complete genometranscriptional regulator of cryptic genes for curli formation and fibronectin binding4e-2199.8
NC_014029:3633955:363759036375903637991402Yersinia pestis Z176003 chromosome, complete genomecurlin genes regulatory protein4e-2199.8
NC_017154:3576256:357989135798913580292402Yersinia pestis D106004 chromosome, complete genomecurlin genes regulatory protein4e-2199.8
NC_017160:3560153:356378835637883564189402Yersinia pestis D182038 chromosome, complete genomecurlin genes regulatory protein4e-2199.8
NC_017168:2158839:217446321744632174864402Yersinia pestis A1122 chromosome, complete genomeDNA-binding transcriptional regulator Crl4e-2199.8
NC_017265:3375463:337873333787333379134402Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,DNA-binding transcriptional regulator4e-2199.8
NC_013282:923500:925567925567925956390Cronobacter turicensis, complete genomeSigma factor-binding protein crl2e-2097.8
NC_009708:3542336:354597135459713546372402Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeCrl family transcriptional regulator3e-2097.1
NC_009381:3228500:323136732313673231768402Yersinia pestis Pestoides F chromosome, complete genomeDNA-binding transcriptional regulator Crl6e-2095.9
NC_013508:876431:880255880255880656402Edwardsiella tarda EIB202, complete genomeDNA-binding transcriptional regulator6e-1682.8
NC_012917:3684840:370031837003183700692375Pectobacterium carotovorum subsp. carotovorum PC1, complete genometranscriptional regulator Crl2e-1374.3
NC_004547:3866439:388395338839533884327375Erwinia carotovora subsp. atroseptica SCRI1043, complete genomecurlin genes transcriptional activator2e-1374.3
NC_013421:3752619:376992237699223770296375Pectobacterium wasabiae WPP163, complete genometranscriptional regulator Crl6e-1372.8