Pre_GI: BLASTP Hits

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Query: NC_017328:303987:303987 Shigella flexneri 2002017 chromosome, complete genome

Start: 303987, End: 305231, Length: 1245

Host Lineage: Shigella flexneri; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This organism, along with Shigella sonnei, is the major cause of shigellosis in industrialized countries and is responsible for endemic infections. This genus is named for the Japanese scientist (Shiga) who discovered them in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. Human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, and over 1 million deaths worldwide are attributed to them. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. Extremely virulent organisms that require very few cells in order to cause disease. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_013361:313540:3158083158083170521245Escherichia coli O26:H11 str. 11368 chromosome, complete genomefermentation/respiration switch protein0863
NC_007384:307013:3092813092813105251245Shigella sonnei Ss046, complete genomehypothetical protein0863
NC_010498:301000:3010713010713023151245Escherichia coli SMS-3-5, complete genomefermentation-respiration switch protein0862
NC_008563:287136:2894042894042906481245Escherichia coli APEC O1, complete genomefermentation/respiration switch protein0860
NC_007946:289425:2894252894252906691245Escherichia coli UTI89, complete genomehypothetical protein YafA0860
NC_004431:364000:3646553646553658991245Escherichia coli CFT073, complete genomehypothetical protein0858
NC_011745:291422:2914222914222926661245Escherichia coli ED1a chromosome, complete genomefermentation/respiration switch protein0855
NC_013716:357928:3579283579283591721245Citrobacter rodentium ICC168, complete genomeesterase0789
NC_015761:299386:2999332999333011771245Salmonella bongori NCTC 12419, complete genomehypothetical protein0783
NC_016514:891772:8940548940548952981245Enterobacter cloacae EcWSU1 chromosome, complete genomeprotein YafA0765
NC_014121:1101093:1101093110109311023371245Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, completefermentation/respiration switch protein0764
NC_020063:3690308:3746198374619837474421245Enterobacteriaceae bacterium strain FGI 57, complete genomedienelactone hydrolase-like enzyme0723
NC_014618:3700640:3716833371683337180771245Enterobacter cloacae SCF1 chromosome, complete genomefermentation/respiration switch protein0720
NC_020260:3004500:3020719302071930219661248Cronobacter sakazakii Sp291, complete genomefermentation/respiration switch protein0687
NC_013282:923500:9242269242269255091284Cronobacter turicensis, complete genomeUPF0255 protein CKO_029570683
NC_012917:3684840:3705003370500337062531251Pectobacterium carotovorum subsp. carotovorum PC1, complete genomehypothetical protein1e-165582
NC_004088:1075454:1089753108975310910181266Yersinia pestis KIM, complete genomehypothetical protein4e-165580
NC_010159:3502350:3506446350644635076931248Yersinia pestis Angola, complete genomeesterase YafA1e-164579
NC_010465:3597000:3600288360028836015351248Yersinia pseudotuberculosis YPIII, complete genomeprotein of unknown function DUF1100 hydrolase family protein1e-164579
NC_008149:1002453:1016770101677010180171248Yersinia pestis Nepal516, complete genomehypothetical protein1e-164579
NC_010634:1056441:1071552107155210727991248Yersinia pseudotuberculosis PB1/+, complete genomeprotein of unknown function DUF1100 hydrolase family protein1e-164579
NC_006155:1074298:1089409108940910906561248Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein1e-164579
NC_005810:754340:7695077695077707541248Yersinia pestis biovar Microtus str. 91001, complete genomefermentation/respiration switch protein1e-164579
NC_003143:3583468:3587564358756435888111248Yersinia pestis CO92, complete genomehypothetical protein1e-164579
NC_008150:3015000:3019242301924230204891248Yersinia pestis Antiqua, complete genomehypothetical protein1e-164579
NC_009381:3228500:3231828323182832330751248Yersinia pestis Pestoides F chromosome, complete genomefermentation/respiration switch protein1e-164579
NC_017265:3375463:3379194337919433804411248Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,fermentation/respiration switch protein1e-164579
NC_017168:2158839:2173156217315621744031248Yersinia pestis A1122 chromosome, complete genomefermentation/respiration switch protein1e-164579
NC_017160:3560153:3564249356424935654961248Yersinia pestis D182038 chromosome, complete genomehypothetical protein1e-164579
NC_017154:3576256:3580352358035235815991248Yersinia pestis D106004 chromosome, complete genomehypothetical protein1e-164579
NC_014029:3633955:3638051363805136392981248Yersinia pestis Z176003 chromosome, complete genomehypothetical protein1e-164579
NC_009708:3542336:3546432354643235476791248Yersinia pseudotuberculosis IP 31758 chromosome, complete genomefermentation/respiration switch protein1e-164579
NC_004547:3866439:3884432388443238856821251Erwinia carotovora subsp. atroseptica SCRI1043, complete genomehypothetical protein2e-164578
NC_020211:996497:99905999905910003061248Serratia marcescens WW4, complete genomefermentation-respiration switch protein2e-159561
NC_013508:876431:8789288789288801931266Edwardsiella tarda EIB202, complete genomefermentation/respiration switch protein1e-153542
NC_002944:4163490:4194956419495641960621107Mycobacterium avium subsp. paratuberculosis K-10, complete genomehypothetical protein2e-0653.9