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Query: NC_017328:2090679:2106728 Shigella flexneri 2002017 chromosome, complete genome

Start: 2106728, End: 2108677, Length: 1950

Host Lineage: Shigella flexneri; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This organism, along with Shigella sonnei, is the major cause of shigellosis in industrialized countries and is responsible for endemic infections. This genus is named for the Japanese scientist (Shiga) who discovered them in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. Human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, and over 1 million deaths worldwide are attributed to them. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. Extremely virulent organisms that require very few cells in order to cause disease. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_004337:2035945:2052469205246920544181950Shigella flexneri 2a str. 301, complete genomeputative tail protein01118
NC_004741:2009769:2027802202780220297511950Shigella flexneri 2a str. 2457T, complete genomeputative tail protein01118
NC_010102:1779707:1807241180724118091691929Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,hypothetical protein0652
NC_017046:2026672:2048317204831720502451929Salmonella enterica subsp. enterica serovar Typhimurium str. 798bacteriophage tape-measure protein0651
NC_016863:2029340:2050985205098520529131929Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1hypothetical protein0651
NC_016857:2027311:2048956204895620508841929Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74tail protein0651
NC_016856:2085283:2102793210279321047211929Salmonella enterica subsp. enterica serovar Typhimurium str. 14028Sphage related tail protein0651
NC_016810:2027311:2048956204895620508841929Salmonella enterica subsp. enterica serovar Typhimurium strbacteriophage tape-measure protein0651
NC_011294:2009388:2027673202767320296011929Salmonella enterica subsp. enterica serovar Enteritidis strphage tape-measure protein0650
NC_011205:2137696:2155979215597921579071929Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853tail protein0647
NC_011094:2115750:2134638213463821365661929Salmonella enterica subsp. enterica serovar Schwarzengrund strtail protein0634
NC_003902:3544743:3545197354519735480672871Xanthomonas campestris pv. campestris str. ATCC 33913, completephage-related tail protein5e-86319
NC_014632:1112733:1122927112292711253082382Ilyobacter polytropus DSM 2926 chromosome, complete genomephage tail tape measure protein, TP901 family6e-39162
NC_006300:60484:8300783007856522646Mannheimia succiniciproducens MBEL55E, complete genomehypothetical protein1e-36155
NC_012416:753500:7575847575847597642181Wolbachia sp. wRi, complete genometail tape measure protein3e-36154
NC_015276:2023663:2033767203376720365502784Marinomonas mediterranea MMB-1 chromosome, complete genomephage tail tape measure protein, TP901 family4e-33143
NC_009850:1651410:1658910165891016608141905Arcobacter butzleri RM4018, complete genomephage tail tape measure protein, TP901 family, putative9e-32139
NC_012440:1709416:1714983171498317174122430Persephonella marina EX-H1, complete genomeputative phage-related membrane protein1e-30135
NC_010981:468465:4795274795274817912265Wolbachia pipientis, complete genomePhage tail tape measure protein2e-28128
NC_002978:549454:5531525531525551942043Wolbachia endosymbiont of Drosophila melanogaster, complete genomeprophage P2W3, tail tape measure protein5e-27123
NC_010981:1371265:1409371140937114116622292Wolbachia pipientis, complete genomephage tail tape measure protein6e-27123
NC_010161:1914000:1935932193593219382682337Bartonella tribocorum CIP 105476, complete genomehypothetical protein3e-25117
NC_010161:1324381:1346536134653613488722337Bartonella tribocorum CIP 105476, complete genomehypothetical protein4e-25116
NC_012846:1837924:1859589185958918619252337Bartonella grahamii as4aup, complete genomephage tail protein2e-23110
NC_009436:1466580:1487905148790514895571653Enterobacter sp. 638, complete genomephage tail-like protein2e-1378.2
NC_013766:679906:7027667027667069654200Listeria monocytogenes 08-5578 chromosome, complete genomehypothetical protein3e-1377.4
NC_011750:2928990:294511129451112946016906Escherichia coli IAI39 chromosome, complete genometail protein from Bacteriophage (fragment)3e-1273.9
NC_013921:1396500:1410696141069614132332538Thermoanaerobacter italicus Ab9 chromosome, complete genomephage tail tape measure protein, TP901 family1e-1068.9
NC_008563:2909945:2928314292831429301491836Escherichia coli APEC O1, complete genomebacteriophage V tail protein9e-0962.8
NC_007946:2894793:2913287291328729151221836Escherichia coli UTI89, complete genomebacteriophage V tail protein9e-0962.8
NC_015674:1605923:1630949163094916328591911Helicobacter bizzozeronii CIII-1, complete genomephage tail tape measure family protein1e-0862
NC_009436:2776410:2795017279501727968071791Enterobacter sp. 638, complete genomeTP901 family phage tail tape measure protein2e-0654.7
NC_013170:311045:3191683191683224553288Cryptobacterium curtum DSM 15641, complete genomephage tail tape measure protein, TP901 family3e-0654.3