Pre_GI: BLASTP Hits

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Query: NC_017316:2466244:2480491 Enterococcus faecalis OG1RF chromosome, complete genome

Start: 2480491, End: 2481102, Length: 612

Host Lineage: Enterococcus faecalis; Enterococcus; Enterococcaceae; Lactobacillales; Firmicutes; Bacteria

General Information: This genera consists of organisms typically found in the intestines of mammals, although through fecal contamination they can appear in sewage, soil, and water. They cause a number of infections that are becoming increasingly a problem due to the number of antibiotic resistance mechanisms these organisms have picked up. Both Enterococcus faecalis and Enterococcus faecium cause similar diseases in humans, and are mainly distinguished by their metabolic capabilities. This opportunistic pathogen can cause urinary tract infections, bacteremia (bacteria in the blood), and infective endocarditis (inflammation of the membrane surrounding the heart), similar to infections caused by Enterococcus faecium. Hospital-acquired infections from this organism are on the rise due to the emergence of antiobiotic resistance strains. Enterococcus faecalis produces a cytolysin toxin that is encoded on various mobile genetic elements, pathogenicity islands, and conjugative plasmids. The cytolysin aids in pathogenesis, possibly by causing destruction of cells such as erythrocytes, which allows access to new nutrients for the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_004668:2938000:295273429527342953345612Enterococcus faecalis V583, complete genomehypothetical protein7e-114409
NC_004461:779000:796730796730797341612Staphylococcus epidermidis ATCC 12228, complete genomehypothetical protein2e-33141
NC_013406:2207520:222916122291612229784624Paenibacillus sp. Y412MC10 chromosome, complete genomehypothetical protein3e-28124