Pre_GI: BLASTP Hits

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Query: NC_017297:3939328:3972928 Clostridium botulinum F str. 230613 chromosome, complete genome

Start: 3972928, End: 3974532, Length: 1605

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009699:3940984:3974851397485139768361986Clostridium botulinum F str. Langeland chromosome, complete genomeDHH family protein01038
NC_010516:3903867:3937733393773339397181986Clostridium botulinum B1 str. Okra, complete genomeDHH family protein01033
NC_009698:3706154:3740020374002037420051986Clostridium botulinum A str. Hall chromosome, complete genomeDHH family protein01032
NC_009495:3832500:3866376386637638683611986Clostridium botulinum A str. ATCC 3502 chromosome, complete genomeDHH family protein01032
NC_010520:3938490:3972383397238339743681986Clostridium botulinum A3 str. Loch Maree, complete genomeDHH family protein01031
NC_009706:3882500:3945266394526639472511986Clostridium kluyveri DSM 555 chromosome, complete genomehypothetical protein0640
NC_011837:3814000:3876769387676938787541986Clostridium kluyveri NBRC 12016, complete genomehypothetical protein0640
NC_017295:3901773:3923148392314839251331986Clostridium acetobutylicum EA 2018 chromosome, complete genomeExopolyphosphatase-like domain and PAS domain containing protein2e-139496
NC_015687:3907000:3925379392537939273641986Clostridium acetobutylicum DSM 1731 chromosome, complete genomehypothetical protein2e-139496
NC_003030:3902000:3923797392379739257821986Clostridium acetobutylicum ATCC 824, complete genomeExopolyphosphatase-like domain and PAS domain containing protein, YYBT B.subtilis ortholog2e-139496
NC_014209:2257316:2283643228364322856101968Thermoanaerobacter mathranii subsp. mathranii str. A3 chromosome,phosphoesterase RecJ domain protein1e-104380
NC_010321:2319820:2339436233943623414031968Thermoanaerobacter pseudethanolicus ATCC 33223 chromosome, completephosphoesterase domain-containing protein2e-102373
NC_014964:2301835:2321451232145123234181968Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, completephosphoesterase RecJ domain-containing protein2e-102373
NC_015275:1223088:1237563123756312395722010Clostridium lentocellum DSM 5427 chromosome, complete genomeputative phosphoesterase3e-96353
NC_016935:8716704:8718748871874887207121965Paenibacillus mucilaginosus 3016 chromosome, complete genomehypothetical protein3e-89329
NC_012781:3087467:3098145309814531002022058Eubacterium rectale ATCC 33656, complete genomeDHH subfamily phosphodiesterase8e-85315
NC_019897:4014485:4014485401448540164491965Thermobacillus composti KWC4 chromosome, complete genomensignaling proteim1e-84314
NC_014622:5683400:5703614570361457056021989Paenibacillus polymyxa SC2 chromosome, complete genomediguanylate cyclase and phosphoesterase3e-82306
NC_012778:2015409:2017237201723720193152079Eubacterium eligens ATCC 27750, complete genomehypothetical protein3e-80299
NC_014376:317312:3300963300963321562061Clostridium saccharolyticum WM1 chromosome, complete genomephosphoesterase RecJ domain protein3e-79296
NC_007530:5197854:5210648521064852126211974Bacillus anthracis str. 'Ames Ancestor', complete genomedhh subfamily 1 protein3e-77289
NC_017200:5325977:5338729533872953407021974Bacillus thuringiensis serovar finitimus YBT-020 chromosome,DHH subfamily 1 protein3e-77289
NC_016771:5191937:5204687520468752066601974Bacillus cereus NC7401, complete genomeDHH subfamily 1 protein3e-77289
NC_011658:5239509:5252260525226052542331974Bacillus cereus AH187 chromosome, complete genomeDHH subfamily 1 protein3e-77289
NC_009328:3504454:3526730352673035287061977Geobacillus thermodenitrificans NG80-2 chromosome, complete genomeDHH subfamily 1 protein4e-77289
NC_005945:5202176:5211893521189352138661974Bacillus anthracis str. Sterne, complete genomeDHH subfamily 1 protein3e-77289
NC_006274:5267585:5284144528414452861171974Bacillus cereus E33L, complete genomephosphoesterase, DHH family3e-77289
NC_012472:5239944:5252740525274052547131974Bacillus cereus 03BB102, complete genomeDHH subfamily 1 protein3e-77289
NC_003997:5200805:5210522521052252124951974Bacillus anthracis str. Ames, complete genomeDHH subfamily 1 protein3e-77289
NC_014335:5165211:5178823517882351807961974Bacillus cereus biovar anthracis str. CI chromosome, completeDHH family phosphoesterase with GGDEF domain3e-77289
NC_005957:5203915:5220912522091252228851974Bacillus thuringiensis serovar konkukian str. 97-27, completephosphoesterase, DHH family3e-77289
NC_012659:5200831:5210548521054852125211974Bacillus anthracis str. A0248, complete genomeDHH subfamily 1 protein3e-77289
NC_016779:5189139:5206135520613552081081974Bacillus cereus F837/76 chromosome, complete genomePhosphoesterase3e-77289
NC_004722:5381208:5394913539491353968861974Bacillus cereus ATCC 14579, complete genomephosphoesterase, DHH family protein7e-76285
NC_006582:4256915:4285422428542242873921971Bacillus clausii KSM-K16, complete genomehypothetical protein6e-74278
NC_007168:16431:1643116431183981968Staphylococcus haemolyticus JCSC1435, complete genomehypothetical protein1e-70267
NC_016941:14658:1826218262202291968Staphylococcus aureus subsp. aureus MSHR1132, complete genomehypothetical protein5e-70265
NC_013450:16000:1832818328202951968Staphylococcus aureus subsp. aureus ED98, complete genomehypothetical protein1e-69264
NC_004461:1:1830818308202751968Staphylococcus epidermidis ATCC 12228, complete genomehypothetical protein1e-69264
NC_002976:2580485:2596415259641525983821968Staphylococcus epidermidis RP62A, complete genomeDHH family protein1e-69264
NC_003923:15416:1832218322202891968Staphylococcus aureus subsp. aureus MW2, complete genomehypothetical protein3e-69263
NC_002953:15416:1832218322202891968Staphylococcus aureus subsp. aureus MSSA476, complete genomehypothetical protein3e-69263
NC_017341:14970:1779417794197611968Staphylococcus aureus subsp. aureus str. JKD6008 chromosome,putative bifunctional signaling protein/50S ribosomal protein L93e-69263
NC_017347:16000:1830918309202761968Staphylococcus aureus subsp. aureus T0131 chromosome, completeDHH subfamily 1 protein3e-69263
NC_007622:16000:1830418304202711968Staphylococcus aureus RF122, complete genomehypothetical protein2e-69263
NC_016928:16869:1908319083210501968Staphylococcus aureus subsp. aureus M013 chromosome, completephosphoesterase, DHH family protein2e-69263
NC_017337:16000:1832218322202891968Staphylococcus aureus subsp. aureus ED133 chromosome, completeDHH subfamily 1 protein2e-69263
NC_007795:15414:1831818318202851968Staphylococcus aureus subsp. aureus NCTC 8325, complete genomehypothetical protein4e-69262
NC_017343:16000:1832818328202951968Staphylococcus aureus subsp. aureus ECT-R 2, complete genomeDHHA1 domain protein5e-69262
NC_009632:16238:1845218452204191968Staphylococcus aureus subsp. aureus JH1 chromosome, completephosphoesterase domain-containing protein5e-69262
NC_009487:16169:1838318383203501968Staphylococcus aureus subsp. aureus JH9 chromosome, completehypothetical protein5e-69262
NC_002745:16000:1832818328202951968Staphylococcus aureus subsp. aureus N315, complete genomehypothetical protein5e-69262
NC_009782:16000:1832918329202961968Staphylococcus aureus subsp. aureus Mu3, complete genomehypothetical protein5e-69262
NC_002758:16000:1832918329202961968Staphylococcus aureus subsp. aureus Mu50, complete genomehypothetical protein5e-69262
NC_002951:15441:1834518345203121968Staphylococcus aureus subsp. aureus COL, complete genomeDHH subfamily 1 protein4e-69262
NC_007793:15441:1834518345203121968Staphylococcus aureus subsp. aureus USA300, complete genomeDHH subfamily 1 protein4e-69262
NC_010079:15441:1834518345203121968Staphylococcus aureus subsp. aureus USA300_TCH1516, completeDHH subfamily phosphodiesterase4e-69262
NC_009641:15421:1832518325202921968Staphylococcus aureus subsp. aureus str. Newman chromosome,hypothetical protein4e-69262
NC_016912:15414:1831818318202851968Staphylococcus aureus subsp. aureus VC40 chromosome, completehypothetical protein4e-69262
NC_017338:14886:1779217792197591968Staphylococcus aureus subsp. aureus JKD6159 chromosome, completeputative bifunctional signaling protein/50S ribosomal protein L94e-69262
NC_017342:483359:5001605001605021451986Staphylococcus aureus subsp. aureus TCH60 chromosome, completeDHH family phosphoesterase4e-69262
NC_017351:15413:1831918319202861968Staphylococcus aureus subsp. aureus 11819-97 chromosome, completeDHH family protein4e-69262
NC_002952:15405:1831018310202771968Staphylococcus aureus subsp. aureus MRSA252, complete genomehypothetical protein4e-69262
NC_007929:1805000:1809587180958718116202034Lactobacillus salivarius subsp. salivarius UCC118, complete genomePhosphoesterase, DHH family protein3e-63243
NC_014334:99000:1089461089461109522007Lactobacillus casei str. Zhang chromosome, complete genomesignaling protein (consists of PAS, a modified GGDEF and a DHH family phosphatase domains)5e-58225
NC_008526:74500:1078121078121098182007Lactobacillus casei ATCC 334, complete genomeSignaling protein (consists of PAS, a modified GGDEF and a DHH family phosphatase domains)4e-57223
NC_010163:171148:1869271869271893832457Acholeplasma laidlawii PG-8A chromosome, complete genomebifunctional signaling protein/ribosomal protein L98e-42172
NC_020419:344000:3564253564253574411017Uncultured Termite group 1 bacterium phylotype Rs-D17 DNA, completeexopolyphosphatase-like protein4e-0963.2
NS_000191:344000:3564253564253574411017Uncultured Termite group 1 bacterium phylotype Rs-D17, completeexopolyphosphatase-like protein4e-0963.2
NC_000908:215000:220607220607221563957Mycoplasma genitalium G37, complete genomephosphoesterase, DHH subfamily 12e-0861.2
NC_014387:1175927:118991911899191190875957Butyrivibrio proteoclasticus B316 chromosome 1, complete genomeDHH domain-containing protein4e-0860.5
NC_010184:4425676:444299244429924443924933Bacillus weihenstephanensis KBAB4, complete genomephosphoesterase RecJ domain protein7e-0859.3
NC_000961:473077:478695478695479684990Pyrococcus horikoshii OT3, complete genomehypothetical protein3e-0757.4
NC_017179:1378875:139097913909791391950972Clostridium difficile BI1, complete genomeRNA-binding protein5e-0756.6
NC_006274:4448293:446584744658474466779933Bacillus cereus E33L, complete genomephosphoesterase, DHH family5e-0756.6
NC_013315:1370000:1381166138116613821761011Clostridium difficile CD196 chromosome, complete genomeRNA-binding protein4e-0756.6
NC_000912:175920:179871179871180845975Mycoplasma pneumoniae M129, complete genomeDHH family phosphoesterase5e-0756.2
NC_012804:1372667:140148114014811402464984Thermococcus gammatolerans EJ3, complete genomePhosphoesterase, recJ-like, containing a DHHA1 domain6e-0756.2
NC_014335:4327584:434594743459474346879933Bacillus cereus biovar anthracis str. CI chromosome, completeDHH family phosphoesterase8e-0755.8
NC_007530:4400152:441756744175674418499933Bacillus anthracis str. 'Ames Ancestor', complete genomedhh subfamily 1 protein8e-0755.8
NC_012472:4400420:441499544149954415927933Bacillus cereus 03BB102, complete genomeDHH subfamily 1 protein8e-0755.8
NC_005945:4399756:441812944181294419061933Bacillus anthracis str. Sterne, complete genomeDHH subfamily 1 protein8e-0755.8
NC_003997:4399067:441744044174404418372933Bacillus anthracis str. Ames, complete genomeDHH subfamily 1 protein8e-0755.8
NC_012659:4399094:441746744174674418399933Bacillus anthracis str. A0248, complete genomeDHH subfamily 1 protein8e-0755.8
NC_016779:4361140:437965443796544380586933Bacillus cereus F837/76 chromosome, complete genome3'-to-5' oligoribonuclease A8e-0755.8
NC_011725:4562709:4577318457731845783881071Bacillus cereus B4264 chromosome, complete genomeDHH subfamily 1 protein1e-0655.5
NC_014171:4447856:446625644662564467188933Bacillus thuringiensis BMB171 chromosome, complete genomeDHH family protein phosphoesterase1e-0655.5
NC_011658:4379274:439522443952244396156933Bacillus cereus AH187 chromosome, complete genomeDHH subfamily 1 protein1e-0655.5
NC_016771:4333000:434900743490074349939933Bacillus cereus NC7401, complete genomeDHH subfamily 1 protein1e-0655.5
NC_017200:4401945:442140144214014422333933Bacillus thuringiensis serovar finitimus YBT-020 chromosome,phosphoesterase, DHH family protein1e-0655.5
NC_013928:797714:799557799557800489933Streptococcus mutans NN2025, complete genomehypothetical protein3e-0654.3
NC_016051:766683:789671789671790654984Thermococcus sp. AM4 chromosome, complete genomephosphoesterase recJ-like containing a DHHA1 domain4e-0653.5
NC_010520:2585014:260990126099012610863963Clostridium botulinum A3 str. Loch Maree, complete genomeDHH family protein6e-0652.8
NC_009495:2524000:254714725471472548118972Clostridium botulinum A str. ATCC 3502 chromosome, complete genomeDHH family protein7e-0652.8