Pre_GI: BLASTP Hits

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Query: NC_017297:3939328:3964886 Clostridium botulinum F str. 230613 chromosome, complete genome

Start: 3964886, End: 3966271, Length: 1386

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009699:3940984:3967191396719139685761386Clostridium botulinum F str. Langeland chromosome, complete genomepyridine nucleotide-disulfide oxidoreductase family protein0943
NC_010520:3938490:3964704396470439660891386Clostridium botulinum A3 str. Loch Maree, complete genomepyridine nucleotide-disulphide oxidoreductase family protein0941
NC_010516:3903867:3930066393006639314511386Clostridium botulinum B1 str. Okra, complete genomepyridine nucleotide-disulphide oxidoreductase family protein0940
NC_009698:3706154:3732357373235737337421386Clostridium botulinum A str. Hall chromosome, complete genomepyridine nucleotide-disulfide oxidoreductase0938
NC_009495:3832500:3858713385871338600981386Clostridium botulinum A str. ATCC 3502 chromosome, complete genomepyridine nucleotide-disulfide oxidoreductase0938
NC_013171:342714:3613833613833627561374Anaerococcus prevotii DSM 20548, complete genomehypothetical protein8e-174610
NC_007503:2338110:2370893237089323722781386Carboxydothermus hydrogenoformans Z-2901, complete genomehypothetical protein3e-125448
NC_019978:2293327:2310167231016723115431377Halobacteroides halobius DSM 5150, complete genomeFAD-dependent dehydrogenase4e-122438
NC_010320:2397395:2397395239739523987771383Thermoanaerobacter sp. X514 chromosome, complete genomeFAD dependent oxidoreductase9e-122437
NC_014538:2396559:2396559239655923979411383Thermoanaerobacter sp. X513 chromosome, complete genomehypothetical protein9e-122437
NC_018870:81396:8247982479838761398Thermacetogenium phaeum DSM 12270 chromosome, complete genomeFAD dependent oxidoreductase2e-120432
NC_015589:3852217:3866804386680438682401437Desulfotomaculum ruminis DSM 2154 chromosome, complete genomehypothetical protein2e-115416
NC_014205:17445:2688126881283021422Staphylothermus hellenicus DSM 12710 chromosome, complete genomeFAD dependent oxidoreductase2e-90333
NC_015847:1119666:1143136114313611445871452Methanococcus maripaludis XI chromosome, complete genomehypothetical protein1e-90333
NC_005791:1028500:1050094105009410515451452Methanococcus maripaludis S2, complete genomehypothetical protein5e-90332
NC_009637:302881:3262723262723277231452Methanococcus maripaludis C7 chromosome, complete genomeFAD-dependent pyridine nucleotide-disulfide oxidoreductase5e-89328
NC_016629:2561000:2574954257495425764561503Desulfovibrio africanus str. Walvis Bay chromosome, completeFAD dependent oxidoreductase3e-88325
NC_006138:273237:2944812944812959861506Desulfotalea psychrophila LSv54, complete genomehypothetical protein1e-87324
NC_013943:2547966:2551401255140125527501350Denitrovibrio acetiphilus DSM 12809 chromosome, complete genomeFAD dependent oxidoreductase9e-87321
NC_015738:1768951:1797750179775017991531404Eggerthella sp. YY7918, complete genomeFAD-dependent dehydrogenase3e-85315
NC_013741:302415:3040773040773054861410Archaeoglobus profundus DSM 5631, complete genomeFAD-dependent pyridine nucleotide-disulphide oxidoreductase9e-85314
NC_014363:114239:1279191279191293371419Olsenella uli DSM 7084 chromosome, complete genomeFAD dependent oxidoreductase2e-83310
NC_012804:271459:2770452770452785081464Thermococcus gammatolerans EJ3, complete genomeOxidoreductase2e-81303
NC_016051:1681076:1684756168475616862191464Thermococcus sp. AM4 chromosome, complete genomeoxidoreductase3e-81302
NC_015865:1260461:1281106128110612825721467Thermococcus sp. 4557 chromosome, complete genomedehydrogenase5e-80298
NC_007925:2892371:2898791289879129001341344Rhodopseudomonas palustris BisB18, complete genomeUncharacterized FAD-dependent dehydrogenases-like1e-22108
NC_020291:231853:2443252443252459411617Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomeFAD-dependent dehydrogenase2e-20100
NC_009698:3526359:3541821354182135434191599Clostridium botulinum A str. Hall chromosome, complete genomeoxidoreductase, FAD-binding6e-2099
NC_009697:3629250:3644712364471236463101599Clostridium botulinum A str. ATCC 19397 chromosome, completeoxidoreductase, FAD-binding6e-2099
NC_007103:230872:259722259722260534813Bacillus cereus E33L plasmid pE33L466, complete sequencepossible uncharacterized protein FAD-dependent dehydrogenase9e-2098.6
NC_013131:10370765:1037932510379325103815232199Catenulispora acidiphila DSM 44928, complete genomeDNA polymerase beta domain protein region1e-1998.2
NC_012658:3744000:3759639375963937612371599Clostridium botulinum Ba4 str. 657 chromosome, complete genomeFAD-binding oxidoreductase3e-1996.7
NC_010520:3753875:3769290376929037708881599Clostridium botulinum A3 str. Loch Maree, complete genomeoxidoreductase, FAD-binding6e-1995.9
NC_012563:3921859:3936627393662739382251599Clostridium botulinum A2 str. Kyoto, complete genomeoxidoreductase, FAD-binding7e-1995.5
NC_017297:3752000:3770169377016937717671599Clostridium botulinum F str. 230613 chromosome, complete genomeoxidoreductase, FAD-binding protein1e-1895.1
NC_009699:3753599:3771555377155537731531599Clostridium botulinum F str. Langeland chromosome, complete genomeoxidoreductase, FAD-binding1e-1895.1
NC_010516:3724312:3739776373977637413741599Clostridium botulinum B1 str. Okra, complete genomeoxidoreductase, FAD-binding1e-1895.1
NC_002505:860789:8607898607898624051617Vibrio cholerae O1 biovar eltor str. N16961 chromosome I, completehypothetical protein3e-1687
NC_009457:351512:3515123515123531281617Vibrio cholerae O395 chromosome 2, complete sequencehypothetical protein3e-1687
NC_012578:818241:8182418182418198571617Vibrio cholerae M66-2 chromosome I, complete sequencehypothetical protein3e-1687
NC_012582:882931:8829318829318845471617Vibrio cholerae O395 chromosome chromosome I, complete sequencehypothetical protein3e-1687
NC_012668:2744393:2801399280139928030151617Vibrio cholerae MJ-1236 chromosome 1, complete sequenceNAD(FAD)-utilizing dehydrogenase3e-1687
NC_016445:338288:3382883382883399041617Vibrio cholerae O1 str. 2010EL-1786 chromosome 1, completehypothetical protein3e-1687
NC_011830:923424:9272659272659288691605Desulfitobacterium hafniense DCB-2, complete genomeFAD dependent oxidoreductase4e-1583.2
NC_014328:4387303:4399090439909044006881599Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative FAD dependent dehydrogenase5e-1582.8
NC_008261:2920999:2930156293015629317571602Clostridium perfringens ATCC 13124, complete genomehypothetical protein8e-1582
NC_015381:3091500:3091826309182630934481623Burkholderia gladioli BSR3 chromosome 1, complete sequenceFAD dependent oxidoreductase1e-1275.1
NC_003228:648669:6587846587846603731590Bacteroides fragilis NCTC 9343, complete genomehypothetical protein4e-1273.2
NC_006347:700838:7109537109537125421590Bacteroides fragilis YCH46, complete genomeNAD-utilizing dehydrogenase4e-1272.8
NC_016776:701684:7144187144187160071590Bacteroides fragilis 638R, complete genomehypothetical protein9e-1168.6