Pre_GI: BLASTP Hits

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Query: NC_017297:3939328:3958952 Clostridium botulinum F str. 230613 chromosome, complete genome

Start: 3958952, End: 3959092, Length: 141

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009698:3706154:37258133725813372588876Clostridium botulinum A str. Hall chromosome, complete genometRNA-Thr2e-0651.2
NC_009495:3832500:38521693852169385224476Clostridium botulinum A str. ATCC 3502 chromosome, complete genometRNA-Thr2e-0651.2
NC_009495:183767:20002320002320009876Clostridium botulinum A str. ATCC 3502 chromosome, complete genometRNA-Thr2e-0651.2
NC_012563:4101000:41206894120689412076476Clostridium botulinum A2 str. Kyoto, complete genometRNA-Thr2e-0651.2
NC_010520:3938490:39581643958164395823976Clostridium botulinum A3 str. Loch Maree, complete genometRNA-Thr2e-0651.2
NC_010520:3938490:39588133958813395888876Clostridium botulinum A3 str. Loch Maree, complete genometRNA-Thr2e-0651.2
NC_004557:81362:82592825928266776Clostridium tetani E88, complete genometRNA-Thr6e-0649.7
NC_009495:183767:20029520029520037076Clostridium botulinum A str. ATCC 3502 chromosome, complete genometRNA-Thr6e-0649.7
NC_009495:3832500:38528183852818385289376Clostridium botulinum A str. ATCC 3502 chromosome, complete genometRNA-Thr6e-0649.7
NC_009698:3706154:37264623726462372653776Clostridium botulinum A str. Hall chromosome, complete genometRNA-Thr6e-0649.7
NC_009699:3940984:39612963961296396137176Clostridium botulinum F str. Langeland chromosome, complete genometRNA-Thr6e-0649.7
NC_012658:3923546:39432243943224394329976Clostridium botulinum Ba4 str. 657 chromosome, complete genometRNA-Thr6e-0649.7
NC_012658:3923546:39438733943873394394876Clostridium botulinum Ba4 str. 657 chromosome, complete genometRNA-Thr6e-0649.7
NC_010516:3903867:39241713924171392424676Clostridium botulinum B1 str. Okra, complete genometRNA-Thr6e-0649.7