Pre_GI: BLASTP Hits

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Query: NC_017297:3752000:3758475 Clostridium botulinum F str. 230613 chromosome, complete genome

Start: 3758475, End: 3759020, Length: 546

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012658:3744000:374794537479453748490546Clostridium botulinum Ba4 str. 657 chromosome, complete genomePTS system glucitol/sorbitol-specific transporter subunit Iic transporter subunit3e-95347
NC_009699:3753599:375986237598623760407546Clostridium botulinum F str. Langeland chromosome, complete genomePTS system glucitol/sorbitol-specific transporter subunit IIC3e-95347
NC_009698:3526359:353012935301293530674546Clostridium botulinum A str. Hall chromosome, complete genomePTS system glucitol/sorbitol-specific transporter subunit IIC3e-95347
NC_009697:3629250:363302036330203633565546Clostridium botulinum A str. ATCC 19397 chromosome, completePTS system glucitol/sorbitol-specific transporter subunit IIC3e-95347
NC_010516:3724312:372808337280833728628546Clostridium botulinum B1 str. Okra, complete genomePTS system, glucitol/sorbitol-specific, IIC component3e-95347
NC_010520:3753875:375759537575953758140546Clostridium botulinum A3 str. Loch Maree, complete genomePTS system, glucitol/sorbitol-specific, IIC component3e-95347
NC_012563:3921859:392493439249343925479546Clostridium botulinum A2 str. Kyoto, complete genomePTS system, glucitol/sorbitol-specific, IIC component3e-95347
NC_015637:891842:891842891842892396555Vibrio anguillarum 775 chromosome chromosome II, complete sequencePTS system, glucitol/sorbitol-specific IIC2 component3e-68257
NC_015637:891842:896120896120896683564Vibrio anguillarum 775 chromosome chromosome II, complete sequencePTS system, glucitol/sorbitol-specific IIC2 component4e-64243
NC_014618:1040381:107254210725421073105564Enterobacter cloacae SCF1 chromosome, complete genomePTS system glucitol/sorbitol-specific transporter subunit IIC3e-62237
NC_016818:3986570:400254140025414003089549Rahnella aquatilis CIP 78.65 = ATCC 33071 chromosome, completePTS system glucitol/sorbitol-specific transporter subunit IIC2e-60231
NC_017316:2710021:271002127100212710575555Enterococcus faecalis OG1RF chromosome, complete genomePTS family glucitol (glu) porter component IIC5e-57219
NC_004668:3184319:318839031883903188944555Enterococcus faecalis V583, complete genomePTS system, sorbitol-specific IIC component5e-57219
NC_015389:1782825:179086517908651791434570Coriobacterium glomerans PW2 chromosome, complete genomePTS system, glucitol/sorbitol-specific, IIC subunit2e-52204
NC_007930:180281:183543183543184085543Lactobacillus salivarius subsp. salivarius UCC118 plasmid pMP118,PTS system, glucitol/sorbitol-specific IIC2 component1e-50199
NC_015519:686027:689270689270689797528Tepidanaerobacter sp. Re1 chromosome, complete genomePTS system glucitol/sorbitol-specific transporter subunit IIC3e-49194
NC_014377:1400544:140333514033351403859525Thermosediminibacter oceani DSM 16646 chromosome, complete genomePTS system, glucitol/sorbitol-specific, IIC subunit1e-48192
NC_002570:832480:835748835748836296549Bacillus halodurans C-125, complete genomePTS system, glucitol/sorbitol-specific enzyme II, C2 component (permease)9e-49192
NC_013517:3997448:401395640139564014507552Sebaldella termitidis ATCC 33386, complete genomePTS system, glucitol/sorbitol-specific, IIC subunit2e-43174
NC_012032:1827244:183943218394321839980549Chloroflexus sp. Y-400-fl, complete genomePTS system, glucitol/sorbitol-specific, IIC subunit6e-39159
NC_010175:1825878:183806618380661838614549Chloroflexus aurantiacus J-10-fl, complete genomePTS system, glucitol/sorbitol-specific, IIC subunit6e-39159
NC_009648:3224495:324345932434593243980522Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genomeputative PTS system glucitol/sorbitol-specific enzyme II1e-35149
NC_012731:560199:597002597002597523522Klebsiella pneumoniae NTUH-K2044 chromosome, complete genomeputative glucitol/sorbitol-specific PTS family enzyme II component2e-35148
NC_011083:2847318:286372728637272864248522Salmonella enterica subsp. enterica serovar Heidelberg str. SL476,glucitol/sorbitol permease iic component3e-35147
NC_003197:2870268:288922128892212889742522Salmonella typhimurium LT2, complete genomeputative PTS system glucitol/sorbitol-specific enzyme II3e-35147
NC_016810:2871689:291178729117872912308522Salmonella enterica subsp. enterica serovar Typhimurium strglucitol/sorbitol permease IIC component3e-35147
NC_016856:2896630:290944629094462909967522Salmonella enterica subsp. enterica serovar Typhimurium str. 14028Sputative PTS system glucitol/sorbitol-specific enzyme II3e-35147
NC_016857:2871689:291178729117872912308522Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74putative PTS system glucitol/sorbitol-specific enzyme II3e-35147
NC_016860:2896254:291278729127872913308522Salmonella enterica subsp. enterica serovar Typhimurium strglucitol/sorbitol-specific PTS system IIC protein3e-35147
NC_016863:2844883:285769928576992858220522Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1putative PTS system glucitol/sorbitol-specific enzyme II3e-35147
NC_017046:2896651:291052829105282911049522Salmonella enterica subsp. enterica serovar Typhimurium str. 798glucitol/sorbitol permease IIC component3e-35147
NC_011751:3048490:306331730633173063838522Escherichia coli UMN026 chromosome, complete genomeglucitol/sorbitol permease IIC component from bacteriophage origin4e-33140
NC_014624:171394:174305174305174877573Eubacterium limosum KIST612 chromosome, complete genomehypothetical protein1e-27122