Pre_GI: BLASTP Hits

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Query: NC_017297:3752000:3756877 Clostridium botulinum F str. 230613 chromosome, complete genome

Start: 3756877, End: 3757242, Length: 366

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009699:3753599:375826437582643758629366Clostridium botulinum F str. Langeland chromosome, complete genomePTS system glucitol/sorbitol-specific transporter subunit IIA3e-64243
NC_010516:3724312:372648437264843726849366Clostridium botulinum B1 str. Okra, complete genomePTS system, glucitol/sorbitol-specific, IIA component3e-64243
NC_009698:3526359:352853135285313528896366Clostridium botulinum A str. Hall chromosome, complete genomePTS system glucitol/sorbitol-specific transporter subunit IIA5e-64242
NC_009697:3629250:363142236314223631787366Clostridium botulinum A str. ATCC 19397 chromosome, completePTS system glucitol/sorbitol-specific transporter subunit IIA5e-64242
NC_012563:3921859:392333639233363923701366Clostridium botulinum A2 str. Kyoto, complete genomePTS system, glucitol/sorbitol-specific, IIA component2e-63240
NC_012658:3744000:374634737463473746712366Clostridium botulinum Ba4 str. 657 chromosome, complete genomePTS system glucitol/sorbitol-specific transporter subunit IIA3e-63239
NC_010520:3753875:375604737560473756412366Clostridium botulinum A3 str. Loch Maree, complete genomePTS system, glucitol/sorbitol-specific, IIA component2e-62236
NC_007930:180281:182084182084182464381Lactobacillus salivarius subsp. salivarius UCC118 plasmid pMP118,PTS system, glucitol/sorbitol-specific IIA component7e-23105
NC_014377:1400544:140190014019001402262363Thermosediminibacter oceani DSM 16646 chromosome, complete genomePTS system glucitol/sorbitol-specific IIA component5e-22103
NC_004668:3184319:318699731869973187353357Enterococcus faecalis V583, complete genomePTS system, sorbitol-specific IIA component6e-22102
NC_014624:171394:175874175874176233360Eubacterium limosum KIST612 chromosome, complete genomehypothetical protein4e-2199.8
NC_016818:3986570:400113140011314001493363Rahnella aquatilis CIP 78.65 = ATCC 33071 chromosome, completephosphotransferase system sorbitol-specific component IIA2e-2098.2
NC_014618:1040381:107120910712091071571363Enterobacter cloacae SCF1 chromosome, complete genomePTS system glucitol/sorbitol-specific transporter subunit IIA2e-1994.7
NC_015389:1782825:178938517893851789768384Coriobacterium glomerans PW2 chromosome, complete genomePTS system glucitol/sorbitol-specific IIA component2e-1994.4
NC_002570:832480:837342837342837719378Bacillus halodurans C-125, complete genomePTS system, glucitol-specific enzyme III1e-1891.7
NC_012032:1827244:183804518380451838410366Chloroflexus sp. Y-400-fl, complete genomePTS system glucitol/sorbitol-specific IIA component7e-1785.9
NC_010175:1825878:183667918366791837044366Chloroflexus aurantiacus J-10-fl, complete genomePTS system glucitol/sorbitol-specific IIA component7e-1785.9
NC_015519:686027:690888690888691253366Tepidanaerobacter sp. Re1 chromosome, complete genomePTS system glucitol/sorbitol-specific transporter subunit IIA9e-1785.5
NC_015637:891842:893416893416893778363Vibrio anguillarum 775 chromosome chromosome II, complete sequencePTS system, glucitol/sorbitol-specific IIA component3e-1684
NC_013517:3997448:401256040125604012916357Sebaldella termitidis ATCC 33386, complete genomePTS system glucitol/sorbitol-specific IIA component5e-1682.8
NC_015637:891842:897658897658898014357Vibrio anguillarum 775 chromosome chromosome II, complete sequencePTS system, glucitol/sorbitol-specific IIA component2e-1270.9
NC_003197:2870268:288973928897392890113375Salmonella typhimurium LT2, complete genomeputative glucitol-specific PTS enzyme III4e-0960.1
NC_016810:2871689:291230529123052912679375Salmonella enterica subsp. enterica serovar Typhimurium strputative PTS enzyme III glucitol4e-0960.1
NC_016856:2896630:290996429099642910338375Salmonella enterica subsp. enterica serovar Typhimurium str. 14028Sputative glucitol-specific PTS enzyme III4e-0960.1
NC_016857:2871689:291230529123052912679375Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74putative glucitol-specific PTS enzyme III4e-0960.1
NC_016860:2896254:291330529133052913679375Salmonella enterica subsp. enterica serovar Typhimurium strputative glucitol-specific PTS system III protein4e-0960.1
NC_016863:2844883:285821728582172858591375Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1putative glucitol-specific PTS enzyme III4e-0960.1
NC_017046:2896651:291104629110462911420375Salmonella enterica subsp. enterica serovar Typhimurium str. 798PTS system glucitol transporter enzyme III4e-0960.1
NC_011083:2847318:286424828642482864619372Salmonella enterica subsp. enterica serovar Heidelberg str. SL476,putative glucitol-specific PTS enzyme III4e-0960.1
NC_009648:3224495:324397732439773244351375Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genomeputative glucitol-specific PTS enzyme III9e-0958.9
NC_012731:560199:596631596631597005375Klebsiella pneumoniae NTUH-K2044 chromosome, complete genomeputative glucitol/sorbitol-specific PTS family enzyme IIA component3e-0857