Pre_GI: BLASTP Hits

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Query: NC_017297:3594000:3615354 Clostridium botulinum F str. 230613 chromosome, complete genome

Start: 3615354, End: 3616772, Length: 1419

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009699:3581376:3616740361674036181581419Clostridium botulinum F str. Langeland chromosome, complete genomecarbon starvation protein CstA0850
NC_009697:3463736:3499097349909735005151419Clostridium botulinum A str. ATCC 19397 chromosome, completecarbon starvation protein CstA0844
NC_009495:3502000:3523109352310935245271419Clostridium botulinum A str. ATCC 3502 chromosome, complete genomecarbon starvation protein CstA0844
NC_012563:3729817:3765172376517237665901419Clostridium botulinum A2 str. Kyoto, complete genomecarbon starvation protein CstA0841
NC_010520:3580000:3600312360031236017301419Clostridium botulinum A3 str. Loch Maree, complete genomecarbon starvation protein CstA0835
NC_014632:336000:3481323481323495441413Ilyobacter polytropus DSM 2926 chromosome, complete genomecarbon starvation protein CstA5e-150531
NC_009615:2902871:2924589292458929259981410Parabacteroides distasonis ATCC 8503 chromosome, complete genomecarbon starvation protein A3e-137488
NC_015437:1685824:1689370168937016907941425Selenomonas sputigena ATCC 35185 chromosome, complete genomecarbon starvation protein CstA1e-131470
NC_016776:3714642:3746759374675937481861428Bacteroides fragilis 638R, complete genomeputative carbon starvation-related membrane protein8e-129460
NC_003228:3690596:3701268370126837026951428Bacteroides fragilis NCTC 9343, complete genomeputative carbon starvation-related membrane protein1e-128459
NC_006347:3760447:3792562379256237939891428Bacteroides fragilis YCH46, complete genomecarbon starvation protein A2e-128459
NC_014632:1248611:1253293125329312546991407Ilyobacter polytropus DSM 2926 chromosome, complete genomecarbon starvation protein CstA1e-125450
NC_015164:960525:9817539817539831801428Bacteroides salanitronis DSM 18170 chromosome, complete genomecarbon starvation protein CstA6e-125447
NC_014933:3688000:3690789369078936922311443Bacteroides helcogenes P 36-108 chromosome, complete genomecarbon starvation protein CstA8e-124444
NC_013192:232778:2341292341292355981470Leptotrichia buccalis DSM 1135, complete genomecarbon starvation protein CstA1e-120433
NC_014829:1376253:1376253137625313776591407Bacillus cellulosilyticus DSM 2522 chromosome, complete genomecarbon starvation protein CstA3e-118425
NC_008577:1015419:1033169103316910346441476Shewanella sp. ANA-3 chromosome 1, complete sequencecarbon starvation protein CstA3e-112405
NC_013410:1651000:1696525169652516979821458Fibrobacter succinogenes subsp. succinogenes S85 chromosome,carbon starvation protein CstA8e-110397
NC_010320:918532:9331829331829348221641Thermoanaerobacter sp. X514 chromosome, complete genomecarbon starvation protein CstA8e-24112
NC_014538:1975385:1979559197955919811991641Thermoanaerobacter sp. X513 chromosome, complete genomecarbon starvation protein CstA8e-24112
NC_015437:2354429:2375381237538123770631683Selenomonas sputigena ATCC 35185 chromosome, complete genomecarbon starvation protein CstA2e-23110
NC_009616:99647:1147741147741164681695Thermosipho melanesiensis BI429 chromosome, complete genomecarbon starvation protein CstA2e-1790.5
NC_014926:608894:6347566347566364141659Thermovibrio ammonificans HB-1 chromosome, complete genomecarbon starvation protein CstA8e-1788.6
NC_009033:133800:1515611515611534471887Staphylothermus marinus F1, complete genomecarbon starvation protein CstA1e-1688.2
NC_003030:1811820:1811820181182018135981779Clostridium acetobutylicum ATCC 824, complete genomeCarbon starvation protein2e-1687.4
NC_015687:1811573:1813420181342018151981779Clostridium acetobutylicum DSM 1731 chromosome, complete genomecarbon starvation protein2e-1687.4
NC_017295:1809386:1811233181123318130111779Clostridium acetobutylicum EA 2018 chromosome, complete genomeCarbon starvation protein2e-1687.4
NC_009828:600349:6026336026336043541722Thermotoga lettingae TMO, complete genomecarbon starvation protein CstA3e-1686.7
NC_014209:1910109:1916490191649019181301641Thermoanaerobacter mathranii subsp. mathranii str. A3 chromosome,carbon starvation protein CstA4e-1583.2
NC_013921:1977444:1983879198387919855191641Thermoanaerobacter italicus Ab9 chromosome, complete genomecarbon starvation protein CstA7e-1582.4
NC_014160:748743:7508847508847527191836Thermosphaera aggregans DSM 11486 chromosome, complete genomecarbon starvation protein CstA8e-1582
NC_009073:803372:8204878204878222621776Pyrobaculum calidifontis JCM 11548, complete genomecarbon starvation protein CstA9e-1582
NC_017187:691769:7064007064007084992100Arcobacter butzleri ED-1, complete genomecarbon starvation protein A4e-1480.1
NC_013194:1040197:1043211104321110452742064Candidatus Accumulibacter phosphatis clade IIA str. UW-1, completecarbon starvation protein CstA5e-1479.7
NC_010515:1678487:1724565172456517266432079Burkholderia cenocepacia MC0-3 chromosome 2, complete sequencecarbon starvation protein CstA1e-1378.2
NC_008543:2666846:2669363266936326714412079Burkholderia cenocepacia HI2424 chromosome 2, complete sequencecarbon starvation protein CstA1e-1378.2
NC_008061:2582000:2595548259554825976262079Burkholderia cenocepacia AU 1054 chromosome 2, complete sequencecarbon starvation protein CstA1e-1378.2
NC_009617:648000:6635376635376653331797Clostridium beijerinckii NCIMB 8052 chromosome, complete genomecarbon starvation protein CstA5e-1376.3
NC_002939:579087:6035976035976055251929Geobacter sulfurreducens PCA, complete genomecarbon starvation protein A7e-1375.9
NC_015731:313676:3181533181533201922040Nitrosomonas sp. Is79A3 chromosome, complete genomecarbon starvation protein CstA7e-1375.9
NC_006510:591339:6347016347016367762076Geobacillus kaustophilus HTA426, complete genomecarbon starvation protein9e-1375.5
NC_006322:2886404:2903203290320329049991797Bacillus licheniformis ATCC 14580, complete genomeCstA1e-1274.7
NC_006270:2886193:2902992290299229047881797Bacillus licheniformis ATCC 14580, complete genomecarbon starvation-induced protein1e-1274.7
NC_014914:439285:4597474597474618582112Taylorella equigenitalis MCE9 chromosome, complete genomeCarbon starvation protein A2e-1274.3
NC_015731:169989:1727301727301748022073Nitrosomonas sp. Is79A3 chromosome, complete genomecarbon starvation protein CstA2e-1274.3
NC_017505:926801:9472139472139492942082Neisseria meningitidis alpha710 chromosome, complete genomecarbon starvation protein A2e-1274.3
NC_017514:761000:7791457791457812262082Neisseria meningitidis M01-240149 chromosome, complete genomecarbon starvation protein A2e-1273.9
NC_002946:1020175:1023468102346810255492082Neisseria gonorrhoeae FA 1090, complete genomeCstA3e-1273.6
NC_017511:543583:5625845625845646652082Neisseria gonorrhoeae TCDC-NG08107 chromosome, complete genomeprotein CstA3e-1273.6
NC_011035:566980:5863345863345884152082Neisseria gonorrhoeae NCCP11945 chromosome, complete genomeprotein CstA3e-1273.6
NC_012779:2664849:2681511268151126836192109Edwardsiella ictaluri 93-146, complete genomecarbon starvation protein A, putative5e-1272.8
NC_008752:4665699:4683776468377646858392064Acidovorax avenae subsp. citrulli AAC00-1, complete genomecarbon starvation protein CstA1e-1171.6
NC_015856:4975815:4995045499504549971172073Collimonas fungivorans Ter331 chromosome, complete genomecarbon starvation protein A1e-1171.2
NC_012968:381771:4006914006914027602070Methylotenera mobilis JLW8, complete genomecarbon starvation protein CstA1e-1171.2
NC_016831:4556761:4572392457239245744432052Salmonella enterica subsp. enterica serovar Gallinarum/pullorumputative carbon starvation protein2e-1170.9
NC_011294:4604283:4619782461978246219322151Salmonella enterica subsp. enterica serovar Enteritidis strcarbon starvation protein2e-1170.9
NC_011274:4577402:4593033459303345951832151Salmonella enterica subsp. enterica serovar Gallinarum str. 287/91carbon starvation protein2e-1170.9
NC_011205:4761598:4777089477708947792392151Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853carbon starvation family protein2e-1170.9
NC_005966:2157677:2174000217400021761052106Acinetobacter sp. ADP1, complete genomestarvation-induced protein involved in peptide utilization during carbon starvation3e-1170.5
NC_010468:4059436:4063062406306240652122151Escherichia coli ATCC 8739, complete genomecarbon starvation protein CstA2e-1170.5
NC_009832:622969:6458276458276480072181Serratia proteamaculans 568, complete genomecarbon starvation protein CstA8e-1168.9
NC_013595:3952196:3968911396891139710492139Streptosporangium roseum DSM 43021, complete genomecarbon starvation protein CstA1e-1068.2
NC_009342:841500:8567608567608590392280Corynebacterium glutamicum R chromosome, complete genomehypothetical protein2e-1067.8
NC_015567:547500:5727345727345749142181Serratia sp. AS9 chromosome, complete genomecarbon starvation protein CstA5e-1066.2
NC_015566:547387:5725485725485747282181Serratia sp. AS12 chromosome, complete genomecarbon starvation protein CstA5e-1066.2
NC_012880:1091486:1094152109415210963022151Dickeya dadantii Ech703, complete genomecarbon starvation protein CstA2e-0964.3