Pre_GI: BLASTP Hits

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Query: NC_017297:3594000:3609617 Clostridium botulinum F str. 230613 chromosome, complete genome

Start: 3609617, End: 3610249, Length: 633

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009699:3581376:361100336110033611635633Clostridium botulinum F str. Langeland chromosome, complete genomeredox-sensing transcriptional repressor Rex4e-105380
NC_009697:3463736:349336034933603493992633Clostridium botulinum A str. ATCC 19397 chromosome, completeredox-sensing transcriptional repressor Rex4e-105380
NC_009495:3502000:351737235173723518004633Clostridium botulinum A str. ATCC 3502 chromosome, complete genomeredox-sensing transcriptional repressor Rex4e-105380
NC_012563:3729817:375944237594423760074633Clostridium botulinum A2 str. Kyoto, complete genometranscriptional regulator, Rex family4e-105380
NC_010520:3580000:359457635945763595208633Clostridium botulinum A3 str. Loch Maree, complete genometranscriptional regulator, Rex family1e-104378
NC_004557:2552418:256762825676282568263636Clostridium tetani E88, complete genomeredox-sensing transcriptional repressor Rex8e-80296
NC_021182:1473535:147827514782751478916642Clostridium pasteurianum BC1, complete genomeAT-rich DNA-binding protein8e-77286
NC_009617:385000:386403386403387038636Clostridium beijerinckii NCIMB 8052 chromosome, complete genomeredox-sensing transcriptional repressor Rex2e-76285
NC_020291:491000:500649500649501284636Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomeredox-sensing transcriptional repressor Rex7e-75280
NC_010723:371741:375524375524376156633Clostridium botulinum E3 str. Alaska E43, complete genomeredox-sensing transcriptional repressor rex1e-74279
NC_010674:370629:380146380146380778633Clostridium botulinum B str. Eklund 17B, complete genomeredox-sensing transcriptional repressor rex1e-74278
NC_008262:2498000:251243625124362513074639Clostridium perfringens SM101, complete genomeDNA-binding protein3e-74277
NC_014393:3650957:366373136637313664354624Clostridium cellulovorans 743B chromosome, complete genomeCoA-binding domain-containing protein7e-71266
NC_016048:2055199:205908420590842059713630Oscillibacter valericigenes Sjm18-20, complete genomeredox-sensing transcriptional repressor Rex3e-38158
NC_014377:669216:687535687535688167633Thermosediminibacter oceani DSM 16646 chromosome, complete genomeCoA-binding domain protein4e-37154
NC_015873:1119500:111953511195351120170636Megasphaera elsdenii DSM 20460, complete genomeredox-sensing transcriptional repressor rex7e-36150
NC_014654:391201:408863408863409510648Halanaerobium sp. 'sapolanicus' chromosome, complete genomeCoA-binding domain protein6e-34144
NC_011899:2165814:218852321885232189170648Halothermothrix orenii H 168, complete genomeredox-sensing transcriptional repressor Rex3e-31135
NC_015759:1117122:111977911197791120414636Weissella koreensis KACC 15510 chromosome, complete genomeredox-sensing transcriptional repressor Rex8e-26117
NC_020995:2636519:265310726531072653853747Enterococcus casseliflavus EC20, complete genomeredox-sensing transcriptional repressor rex 12e-24112
NC_008025:669281:679673679673680368696Deinococcus geothermalis DSM 11300, complete genomeCoA-binding9e-24110
NC_014376:869749:882315882315882983669Clostridium saccharolyticum WM1 chromosome, complete genomeCoA-binding domain protein1e-22106
NC_021175:964224:967037967037967684648Streptococcus oligofermentans AS 1.3089, complete genomeredox-sensing transcriptional repressor Rex6e-22103
NC_007498:1848437:185937418593741860021648Pelobacter carbinolicus DSM 2380, complete genomeputative DNA-binding protein p254e-21101
NC_011567:204772:224680224680225315636Anoxybacillus flavithermus WK1, complete genomeAT-rich DNA-binding protein4e-21101
NC_006347:4562242:457860545786054579261657Bacteroides fragilis YCH46, complete genomeredox-sensing transcriptional repressor Rex1e-2099.8
NC_003228:4449072:446460144646014465263663Bacteroides fragilis NCTC 9343, complete genomeredox-sensing transcriptional repressor Rex1e-2099.8
NC_016776:4525065:454473045447304545392663Bacteroides fragilis 638R, complete genomehypothetical protein1e-2099.8
NC_017208:256163:258284258284258913630Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeredox-sensing transcriptional repressor Rex2e-2099
NC_014171:235558:257804257804258433630Bacillus thuringiensis BMB171 chromosome, complete genomeredox-sensing transcriptional repressor Rex2e-2099
NC_014824:133065:138999138999139601603Ruminococcus albus 7 plasmid pRUMAL01, complete sequenceCoA-binding domain protein5e-1994.4
NC_020272:3325000:334033933403393340986648Bacillus amyloliquefaciens IT-45, complete genomeredox-sensing transcriptional repressor Rex5e-1890.9
NC_010999:1381497:140352014035201404173654Lactobacillus casei, complete genomeRedox-sensing transcriptional repressor rex9e-1787
NC_013192:171000:172578172578173243666Leptotrichia buccalis DSM 1135, complete genomeRex DNA-binding domain protein2e-1479
NC_015601:1107961:111449311144931115116624Erysipelothrix rhusiopathiae str. Fujisawa, complete genomeredox-sensing transcriptional repressor Rex3e-1478.6