Pre_GI: BLASTP Hits

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Query: NC_017297:3178378:3178860 Clostridium botulinum F str. 230613 chromosome, complete genome

Start: 3178860, End: 3179558, Length: 699

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009633:3055413:306194030619403062638699Alkaliphilus metalliredigens QYMF chromosome, complete genomediacylglycerol kinase1e-55216
NC_008600:4101748:410314441031444103497354Bacillus thuringiensis str. Al Hakam, complete genomediacylglycerol kinase2e-1789
NC_011658:4107501:410889741088974109250354Bacillus cereus AH187 chromosome, complete genomediacylglycerol kinase6e-1787.8
NC_020134:586840:586840586840587220381Clostridium stercorarium subsp. stercorarium DSM 8532, completediacylglycerol kinase3e-1272
NC_009615:2311352:231492723149272315304378Parabacteroides distasonis ATCC 8503 chromosome, complete genomediacylglycerol kinase1e-0963.5
NC_011661:1332309:134767813476781348040363Dictyoglomus turgidum DSM 6724, complete genomediacylglycerol kinase2e-0756.2
NC_014393:1782811:178281117828111783521711Clostridium cellulovorans 743B chromosome, complete genomediacylglycerol kinase2e-74278
NC_012472:4119192:412058841205884120941354Bacillus cereus 03BB102, complete genomediacylglycerol kinase2e-1789
NC_011969:4001489:400398540039854004338354Bacillus cereus Q1 chromosome, complete genomediacylglycerol kinase6e-1787.8
NC_011898:649000:669696669696670070375Clostridium cellulolyticum H10, complete genomediacylglycerol kinase2e-1582.8
NC_012004:470492:472762472762473166405Streptococcus uberis 0140J, complete genomediacylglycerol kinase6e-1064.3
NC_013926:1037681:105254610525461052908363Aciduliprofundum boonei T469 chromosome, complete genomediacylglycerol kinase1e-0756.6
NC_013016:1441424:146191514619151462298384Neisseria meningitidis alpha14 chromosome, complete genomeDiacylglycerol kinase5e-0651.6
NC_016771:4059445:406268140626814063034354Bacillus cereus NC7401, complete genomediacylglycerol kinase6e-1787.8
NC_009674:3073564:307487630748763075229354Bacillus cytotoxicus NVH 391-98 chromosome, complete genomediacylglycerol kinase1e-1583.2
NC_015164:3144745:314702231470223147390369Bacteroides salanitronis DSM 18170 chromosome, complete genomediacylglycerol kinase3e-0858.9
NC_007575:319119:321199321199321558360Sulfurimonas denitrificans DSM 1251, complete genomediacylglycerol kinase2e-0652.4
NC_013517:2055071:207477820747782075566789Sebaldella termitidis ATCC 33386, complete genomediacylglycerol kinase4e-42171
NC_005945:4116978:411662841166284116981354Bacillus anthracis str. Sterne, complete genomediacylglycerol kinase2e-1789
NC_003909:4064904:406455440645544064907354Bacillus cereus ATCC 10987, complete genomediacylglycerol kinase2e-1685.9
NC_002570:1426000:145005014500501450442393Bacillus halodurans C-125, complete genomediacylglycerol kinase7e-0960.8
NC_007622:1558753:155916815591681559512345Staphylococcus aureus RF122, complete genomediacylglycerol kinase2e-0652.8
NC_020291:1014333:103337210333721034073702Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomediacylglycerol kinase DgkA3e-82304
NC_011999:1320159:132365913236591324006348Macrococcus caseolyticus JCSC5402, complete genomediacylglycerol kinase homolog4e-1271.6
NC_009698:3006500:300812030081203008818699Clostridium botulinum A str. Hall chromosome, complete genomediacylglycerol kinase/PAP2 family protein3e-121434
NC_010516:3196158:319615831961583196856699Clostridium botulinum B1 str. Okra, complete genomediacylglycerol kinase/PAP2 family protein3e-121434
NC_009699:3178222:317870431787043179402699Clostridium botulinum F str. Langeland chromosome, complete genomediacylglycerol kinase/PAP2 family protein3e-121434
NC_010520:3204480:320448032044803205178699Clostridium botulinum A3 str. Loch Maree, complete genomediacylglycerol kinase/PAP2 family protein3e-121434
NC_012658:3213498:321349832134983214196699Clostridium botulinum Ba4 str. 657 chromosome, complete genomediacylglycerol kinase/PAP2 family protein3e-121434
NC_009495:3138355:313835531383553139053699Clostridium botulinum A str. ATCC 3502 chromosome, complete genomediacylglycerol kinase/PAP2 family protein3e-121434
NC_009697:3071198:307119830711983071896699Clostridium botulinum A str. ATCC 19397 chromosome, completediacylglycerol kinase/PAP2 family protein3e-121434
NC_012563:3374904:337490433749043375602699Clostridium botulinum A2 str. Kyoto, complete genomediacylglycerol kinase/PAP2 family protein3e-121434
NC_013171:342714:3737193737193750591341Anaerococcus prevotii DSM 20548, complete genomeprotein of unknown function UPF00548e-29127
NC_014734:2285762:230840823084082308770363Paludibacter propionicigenes WB4 chromosome, complete genomeundecaprenol kinase8e-1270.5