Pre_GI: BLASTP Hits

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Query: NC_017297:2143000:2145099 Clostridium botulinum F str. 230613 chromosome, complete genome

Start: 2145099, End: 2147183, Length: 2085

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009699:2142177:2144997214499721470842088Clostridium botulinum F str. Langeland chromosome, complete genomecarbohydrate binding protein01320
NC_010516:2093901:2094918209491820970052088Clostridium botulinum B1 str. Okra, complete genomecarbohydrate binding protein01310
NC_012658:2138791:2141388214138821434752088Clostridium botulinum Ba4 str. 657 chromosome, complete genomecarbohydrate binding protein01288
NC_009698:2012500:2015710201571020177582049Clostridium botulinum A str. Hall chromosome, complete genomecarbohydrate binding protein01151
NC_009697:2012500:2015493201549320175412049Clostridium botulinum A str. ATCC 19397 chromosome, completecarbohydrate binding protein01151
NC_009495:2085000:2086852208685220889002049Clostridium botulinum A str. ATCC 3502 chromosome, complete genomesecreted carbohydrate-binding protein01151
NC_012563:2230403:2233561223356122356092049Clostridium botulinum A2 str. Kyoto, complete genomecarbohydrate binding protein01151
NC_012658:2138791:2152363215236321545822220Clostridium botulinum Ba4 str. 657 chromosome, complete genomehypothetical protein0968
NC_017297:2143000:2156080215608021582992220Clostridium botulinum F str. 230613 chromosome, complete genomehypothetical protein0963
NC_009699:2142177:2155980215598021581992220Clostridium botulinum F str. Langeland chromosome, complete genomehypothetical protein0963
NC_010516:2093901:2105737210573721079562220Clostridium botulinum B1 str. Okra, complete genomehypothetical protein0961
NC_009698:2012500:2026500202650020287192220Clostridium botulinum A str. Hall chromosome, complete genomehypothetical protein0961
NC_009697:2012500:2026281202628120285002220Clostridium botulinum A str. ATCC 19397 chromosome, completehypothetical protein0961
NC_009495:2085000:2097640209764020998592220Clostridium botulinum A str. ATCC 3502 chromosome, complete genomesecreted protein0961
NC_012563:2230403:2244352224435222465712220Clostridium botulinum A2 str. Kyoto, complete genomehypothetical protein0956
NS_000195:219785:2708002708002747353936Candidatus Cloacamonas acidaminovoranshypothetical protein; putative signal peptide2e-91337
NC_002939:3303989:3305627330562733111045478Geobacter sulfurreducens PCA, complete genomehypothetical protein4e-1584
NC_020291:1122282:1124174112417411256611488Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomesecreted metalloprotease9e-1582.8
NC_014410:2329838:2348586234858623503011716Thermoanaerobacterium thermosaccharolyticum DSM 571 chromosome,glycoside hydrolase family 188e-1169.7
NC_012658:1658505:1661991166199116634901500Clostridium botulinum Ba4 str. 657 chromosome, complete genomechitinase A9e-0859.3
NC_005140:660305:6637946637946676543861Vibrio vulnificus YJ016 chromosome II, complete sequencehypothetical protein9e-0756.2
NC_005085:2774370:2792035279203527931951161Chromobacterium violaceum ATCC 12472, complete genomecarbohydrate-binding protein9e-0756.2
NC_004460:81687:8528785287890363750Vibrio vulnificus CMCP6 chromosome II, complete sequencehypothetical protein9e-0756.2
NC_014966:638355:6418456418456457053861Vibrio vulnificus MO6-24/O chromosome II, complete sequencehypothetical protein8e-0756.2
NC_017093:8518961:853760685376068538439834Actinoplanes missouriensis 431, complete genomeputative secreted chitin-binding protein1e-0655.8
NC_014484:1690272:1735547173554717374811935Spirochaeta thermophila DSM 6192 chromosome, complete genomeglycosyl hydrolases family 181e-0655.8
NC_013406:4323338:4329172432917243306351464Paenibacillus sp. Y412MC10 chromosome, complete genomeFibronectin type III domain-containing protein5e-0653.5
NC_014624:370030:3700303700303730923063Eubacterium limosum KIST612 chromosome, complete genomeM6 family metalloprotease domain-containing protein9e-0652.8