Pre_GI: BLASTP Hits

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Query: NC_017297:1280963:1281681 Clostridium botulinum F str. 230613 chromosome, complete genome

Start: 1281681, End: 1281992, Length: 312

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012563:1348500:135103713510371351348312Clostridium botulinum A2 str. Kyoto, complete genomerhodanese domain protein3e-52203
NC_014387:3227875:324499132449913245794804Butyrivibrio proteoclasticus B316 chromosome 1, complete genomerhodanese domain-containing protein6e-1786.3
NC_014828:637523:640898640898641248351Ethanoligenens harbinense YUAN-3 chromosome, complete genomeRhodanese domain protein1e-1685.5
NC_015557:278000:278671278671278982312Hydrogenobaculum sp. 3684 chromosome, complete genomeRhodanese-like protein2e-1374.7
NC_020411:278000:278703278703279014312Hydrogenobaculum sp. HO, complete genomethiosulfate sulfurtransferase2e-1374.7
NC_015587:278000:278707278707279018312Hydrogenobaculum sp. SHO chromosome, complete genomeRhodanese-like protein2e-1374.7
NC_019897:4014485:402667340266734027014342Thermobacillus composti KWC4 chromosome, complete genomerhodanese-related sulfurtransferase4e-1270.1
NC_011979:537862:559561559561559938378Geobacter sp. FRC-32, complete genomeRhodanese domain protein6e-1269.7
NC_018876:307464:3248153248153261851371Methanolobus psychrophilus R15 chromosome, complete genomemetallo-beta-lactamase7e-1269.3
NC_006274:765870:776909776909777469561Bacillus cereus E33L, complete genomeconserved hypothetical protein; probable rhodanese domain8e-1268.9
NC_006511:1243817:126598512659851266299315Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCCphage shock protein E precursor1e-1168.2
NC_020389:1936000:195744119574411957884444Methanosarcina mazei Tuc01, complete genomehypothetical protein3e-1167.4
NC_014836:155924:171715171715172143429Desulfurispirillum indicum S5 chromosome, complete genomeRhodanese domain-containing protein3e-1167
NC_013851:3392644:341470234147023415124423Allochromatium vinosum DSM 180 chromosome, complete genomeRhodanese domain protein4e-1167
NC_008554:484267:487330487330488166837Syntrophobacter fumaroxidans MPOB, complete genomeRhodanese domain protein8e-1165.9
NC_003552:3092456:309911230991123099660549Methanosarcina acetivorans C2A, complete genomehypothetical protein1e-1065.5
NC_013205:1275012:130177013017701302162393Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446,Rhodanese domain protein2e-1064.7
NC_014376:4369666:438447743844774384791315Clostridium saccharolyticum WM1 chromosome, complete genomeRhodanese domain protein2e-1064.7
NC_012440:1841315:186556218655621865942381Persephonella marina EX-H1, complete genomehypothetical protein2e-1064.3
NC_015949:1887478:1903596190359619052841689Caldicellulosiruptor lactoaceticus 6A chromosome, complete genomeFAD-dependent pyridine nucleotide-disulfide oxidoreductase3e-1063.9
NC_008601:1151653:117115811711581171907750Francisella tularensis subsp. novicida U112, complete genomerhodanese-like family protein4e-1063.5
NC_014831:285759:294172294172294513342Thermaerobacter marianensis DSM 12885 chromosome, complete genomeRhodanese domain protein4e-1063.5
NC_009464:379377:405172405172405516345Uncultured methanogenic archaeon RC-I, complete genomepredicted rhodanese-like protein5e-1063.2
NC_006510:2110430:211102321110232111319297Geobacillus kaustophilus HTA426, complete genomehypothetical protein4e-1063.2
NC_013411:2951559:295333929533392953635297Geobacillus sp. Y412MC61, complete genomeRhodanese domain protein4e-1063.2
NC_014915:2092678:209327120932712093567297Geobacillus sp. Y412MC52 chromosome, complete genomeRhodanese domain protein4e-1063.2
NC_019897:4014485:403059840305984030969372Thermobacillus composti KWC4 chromosome, complete genomerhodanese-related sulfurtransferase6e-1062.8
NC_020210:2133996:213662721366272136923297Geobacillus sp. GHH01, complete genomeUPF0033 family protein9e-1062.4
NC_017208:823540:835831835831836190360Bacillus thuringiensis serovar chinensis CT-43 chromosome, completerhodanese-related sulfurtransferase9e-1062
NC_013440:5944935:595612859561285957099972Haliangium ochraceum DSM 14365, complete genomeRhodanese domain protein1e-0961.6
NC_017208:823540:833804833804834364561Bacillus thuringiensis serovar chinensis CT-43 chromosome, completemolybdopterin biosynthesis MoeB1e-0961.6
NC_009465:938378:942804942804943175372Candidatus Vesicomyosocius okutanii HA, complete genomerhodanese family protein2e-0960.8
NC_008610:1068429:107591110759111076198288Candidatus Ruthia magnifica str. Cm (Calyptogena magnifica),Rhodanese domain protein3e-0960.5
NC_008712:250240:251139251139251762624Arthrobacter aurescens TC1 plasmid TC1, complete sequenceputative Rhodanese-like domain protein3e-0960.5
NC_016628:1190366:120513512051351205509375Vibrio furnissii NCTC 11218 chromosome 2, complete sequencephage shock protein E3e-0960.5
NC_013720:545829:565982565982566902921Pirellula staleyi DSM 6068, complete genomeRhodanese domain protein4e-0960.1
NC_009328:2083386:210089221008922101188297Geobacillus thermodenitrificans NG80-2 chromosome, complete genomemolybdopterin biosynthesis MoeB protein-like protein4e-0960.1
NC_004369:41236:584065840659065660Corynebacterium efficiens YS-314, complete genomehypothetical protein7e-0959.3
NC_019842:484933:518723518723519289567Bacillus amyloliquefaciens subsp. plantarum AS43.3 chromosome,hypothetical protein1e-0858.5
NC_021175:964224:985854985854986162309Streptococcus oligofermentans AS 1.3089, complete genomerhodanese family protein1e-0858.5
NC_006274:765870:778935778935779294360Bacillus cereus E33L, complete genomerhodanese-like domain protein1e-0858.5
NC_012440:1080675:109974410997441100151408Persephonella marina EX-H1, complete genomerhodanese domain protein1e-0858.2
NC_013739:5012394:501521950152195015563345Conexibacter woesei DSM 14684, complete genomeRhodanese domain protein2e-0858.2
NC_006510:2110430:211043021104302110999570Geobacillus kaustophilus HTA426, complete genomehypothetical protein2e-0857.8
NC_013411:2951559:295274629527462953315570Geobacillus sp. Y412MC61, complete genomeSirA family protein2e-0857.4
NC_014915:2092678:209267820926782093247570Geobacillus sp. Y412MC52 chromosome, complete genomeSirA-like domain-containing protein2e-0857.4
NC_014152:927969:9433949433949450701677Thermincola sp. JR, complete genomeFAD-dependent pyridine nucleotide-disulfide oxidoreductase2e-0857.4
NC_008095:5312926:531462553146255314981357Myxococcus xanthus DK 1622, complete genomerhodanese-like domain protein4e-0857
NC_019896:1483073:151347915134791514036558Bacillus subtilis subsp. subtilis str. BSP1 chromosome, completehypothetical protein3e-0857
NC_015636:468500:471131471131471454324Methanothermococcus okinawensis IH1 chromosome, complete genomeRhodanese-like protein3e-0857
NC_006270:2657726:268077026807702681342573Bacillus licheniformis ATCC 14580, complete genomeYrkF3e-0857
NC_006322:2658587:268163026816302682202573Bacillus licheniformis ATCC 14580, complete genomeYrkF3e-0857
NC_007498:2638671:265505926550592655901843Pelobacter carbinolicus DSM 2380, complete genomerhodanese-related sulfurtransferase4e-0856.6
NC_017208:823540:836205836205836501297Bacillus thuringiensis serovar chinensis CT-43 chromosome, completemolybdopterin biosynthesis MoeB4e-0856.6
NC_020210:2133996:213603621360362136605570Geobacillus sp. GHH01, complete genomeUPF0033 family protein4e-0856.6
NC_019940:2893535:291515729151572915483327Thioflavicoccus mobilis 8321 chromosome, complete genomerhodanese-related sulfurtransferase6e-0856.2
NC_014733:107394:112664112664113029366Methylovorus sp. MP688 chromosome, complete genomerhodanese domain protein8e-0855.8
NC_008577:44184:619946199462470477Shewanella sp. ANA-3 chromosome 1, complete sequenceRhodanese domain protein7e-0855.8
NC_009725:496443:524715524715525281567Bacillus amyloliquefaciens FZB42, complete genomeYrkF7e-0855.8
NC_000964:2702376:271180327118032712360558Bacillus subtilis subsp. subtilis str. 168, complete genomehypothetical protein7e-0855.8
NC_006510:2110430:211133221113322111697366Geobacillus kaustophilus HTA426, complete genomehypothetical protein1e-0755.5
NC_009328:2083386:210120121012012101566366Geobacillus thermodenitrificans NG80-2 chromosome, complete genomerhodanese-related sulfurtransferase-like protein1e-0755.5
NC_009328:2083386:210029921002992100868570Geobacillus thermodenitrificans NG80-2 chromosome, complete genomemolybdopterin biosynthesis MoeB protein-like protein1e-0755.1
NC_014976:684000:696441696441696995555Bacillus subtilis BSn5 chromosome, complete genomeputative rhodanese-related sulfur transferase1e-0755.1
NC_008819:1635838:1657930165793016590751146Prochlorococcus marinus str. NATL1A, complete genomemolybdopterin biosynthesis protein2e-0754.7
NC_009725:496443:524287524287524655369Bacillus amyloliquefaciens FZB42, complete genomeputative rhodanese-like domain protein2e-0754.3
NC_015740:1594376:161599116159911616347357Pseudomonas stutzeri ATCC 17588 = LMG 11199 chromosome, completerhodanese domain-containing protein2e-0754.3
NC_014219:2491021:250853325085332508907375Bacillus selenitireducens MLS10 chromosome, complete genomeRhodanese domain protein2e-0754.3
NC_015740:2614317:264966926496692650049381Pseudomonas stutzeri ATCC 17588 = LMG 11199 chromosome, completerhodanese-like domain-containing protein2e-0754.3
NC_012997:4545875:455071445507144551094381Teredinibacter turnerae T7901, complete genomerhodanese domain protein3e-0753.9
NC_014915:2092678:209358020935802093945366Geobacillus sp. Y412MC52 chromosome, complete genomeRhodanese domain protein4e-0753.5
NC_013411:2951559:295364829536482954013366Geobacillus sp. Y412MC61, complete genomeRhodanese domain protein4e-0753.5
NC_009009:1295607:129965312996531299967315Streptococcus sanguinis SK36, complete genomeRhodanese-like domain protein, putative4e-0753.5
NC_006274:765870:779309779309779605297Bacillus cereus E33L, complete genomerhodanese-like domain protein3e-0753.5
NC_021175:964224:983898983898984191294Streptococcus oligofermentans AS 1.3089, complete genomerhodanese family protein3e-0753.5
NC_019974:1280500:128074912807491281108360Natronococcus occultus SP4, complete genomeRhodanese-related sulfurtransferase5e-0753.1
NC_002951:49535:5477554775558421068Staphylococcus aureus subsp. aureus COL, complete genomehypothetical protein5e-0753.1
NC_015759:726612:739630739630740280651Weissella koreensis KACC 15510 chromosome, complete genomeputative transcriptional regulator5e-0753.1
NC_017337:1829840:184320618432061843517312Staphylococcus aureus subsp. aureus ED133 chromosome, completehypothetical protein5e-0753.1
NC_015519:270637:2736932736932762452553Tepidanaerobacter sp. Re1 chromosome, complete genomeCoA-disulfide reductase8e-0752.4
NC_009848:161373:183390183390183743354Bacillus pumilus SAFR-032, complete genomerhodanese-domain-containing protein8e-0752.4
NC_013526:911909:9123319123319137611431Thermobaculum terrenum ATCC BAA-798 chromosome 2, complete genomebeta-lactamase domain protein8e-0752.4
NC_016616:1336000:133658513365851336998414Dechlorosoma suillum PS chromosome, complete genomeRhodanese-related sulfurtransferase8e-0752.4
NC_021171:4425050:444290044429004443196297Bacillus sp. 1NLA3E, complete genomerhodanese-like protein9e-0752.4
NC_019897:4014485:402701940270194027597579Thermobacillus composti KWC4 chromosome, complete genomerhodanese-related sulfurtransferase9e-0752.4
NC_014831:285759:295755295755296363609Thermaerobacter marianensis DSM 12885 chromosome, complete genomeRhodanese domain protein1e-0652
NC_011025:183287:2253552253552274122058Mycoplasma arthritidis 158L3-1, complete genomerhodanese-like domain protein1e-0651.6
NC_016627:689406:6965666965666990312466Clostridium clariflavum DSM 19732 chromosome, complete genomeNAD(FAD)-dependent dehydrogenase2e-0651.6
NC_009614:769851:780519780519780917399Bacteroides vulgatus ATCC 8482 chromosome, complete genomehypothetical protein2e-0651.2
NC_004461:1465397:148113714811371481448312Staphylococcus epidermidis ATCC 12228, complete genomehypothetical protein2e-0651.2
NC_002976:1361364:137710413771041377415312Staphylococcus epidermidis RP62A, complete genomerhodanese-like domain protein2e-0651.2
NC_013440:5944935:5954874595487459561211248Haliangium ochraceum DSM 14365, complete genomeMethyltransferase type 112e-0651.2
NC_008312:1725763:1743770174377017449451176Trichodesmium erythraeum IMS101, complete genomeUBA/THIF-type NAD/FAD binding fold2e-0651.2
NC_017167:129988:1398461398461409761131Alicyclobacillus acidocaldarius subsp. acidocaldarius Tc-4-1beta-lactamase2e-0650.8
NC_013194:1955582:1959729195972919607931065Candidatus Accumulibacter phosphatis clade IIA str. UW-1, completebeta-lactamase domain protein2e-0650.8
NC_002951:49535:5342853428547561329Staphylococcus aureus subsp. aureus COL, complete genomemetallo-beta-lactamase family protein2e-0650.8
NC_011830:1288984:131851813185181319372855Desulfitobacterium hafniense DCB-2, complete genomeRhodanese domain protein3e-0650.4
NC_008610:1068429:108315310831531083638486Candidatus Ruthia magnifica str. Cm (Calyptogena magnifica),Rhodanese domain protein3e-0650.4
NC_017045:1902582:190519019051901905474285Riemerella anatipestifer ATCC 11845 = DSM 15868 chromosome,rhodanese domain-containing protein3e-0650.4
NC_014738:1742654:174526217452621745546285Riemerella anatipestifer ATCC 11845 = DSM 15868 chromosome,rhodanese domain-containing protein3e-0650.4
NC_014330:2520906:254268125426812543064384Brachyspira pilosicoli 95/1000 chromosome, complete genomerhodanese domain-containing protein5e-0650.1
NC_020134:1783000:1797885179788517995161632Clostridium stercorarium subsp. stercorarium DSM 8532, completeNADH oxidase Nox4e-0650.1
NC_013892:4129500:415066041506604151097438Xenorhabdus bovienii SS-2004 chromosome, complete genomehypothetical protein5e-0649.7
NC_017338:1830790:184225918422591842570312Staphylococcus aureus subsp. aureus JKD6159 chromosome, completerhodanese domain-containing protein8e-0649.3
NC_016912:1732354:174611417461141746425312Staphylococcus aureus subsp. aureus VC40 chromosome, completerhodanese-like domain-containing protein8e-0649.3
NC_009641:1833000:184532418453241845635312Staphylococcus aureus subsp. aureus str. Newman chromosome,hypothetical protein8e-0649.3
NC_003923:1841500:185364718536471853958312Staphylococcus aureus subsp. aureus MW2, complete genomehypothetical protein8e-0649.3
NC_010079:1871915:188554418855441885855312Staphylococcus aureus subsp. aureus USA300_TCH1516, completepossible rhodanese domain sulfurtransferase8e-0649.3
NC_002953:1819411:183298318329831833294312Staphylococcus aureus subsp. aureus MSSA476, complete genomehypothetical protein8e-0649.3
NC_002951:1848684:186248318624831862794312Staphylococcus aureus subsp. aureus COL, complete genomerhodanese-like domain protein8e-0649.3
NC_007795:1774725:178848517884851788796312Staphylococcus aureus subsp. aureus NCTC 8325, complete genomehypothetical protein8e-0649.3
NC_007793:1871165:188479418847941885105312Staphylococcus aureus subsp. aureus USA300, complete genomerhodanese-like domain protein8e-0649.3
NC_017341:1851972:186556418655641865875312Staphylococcus aureus subsp. aureus str. JKD6008 chromosome,rhodanese domain-containing protein8e-0649.3
NC_017347:1852500:186471818647181865029312Staphylococcus aureus subsp. aureus T0131 chromosome, completerhodanese domain sulfurtransferase8e-0649.3
NC_014408:1340016:1364784136478413661301347Methanothermobacter marburgensis str. Marburg chromosome, completehydrolase6e-0649.3
NC_017343:1748620:176205717620571762368312Staphylococcus aureus subsp. aureus ECT-R 2, complete genomerhodanese-like domain-containing protein8e-0649.3
NC_013450:1825010:183844718384471838758312Staphylococcus aureus subsp. aureus ED98, complete genomerhodanese-like domain-containing protein8e-0649.3
NC_009632:1927372:193884219388421939153312Staphylococcus aureus subsp. aureus JH1 chromosome, completerhodanese domain-containing protein8e-0649.3
NC_009487:1925645:193896819389681939279312Staphylococcus aureus subsp. aureus JH9 chromosome, completerhodanese domain-containing protein8e-0649.3
NC_002758:1880323:189364018936401893951312Staphylococcus aureus subsp. aureus Mu50, complete genomehypothetical protein8e-0649.3
NC_009782:1881722:189503918950391895350312Staphylococcus aureus subsp. aureus Mu3, complete genomehypothetical protein8e-0649.3
NC_002745:1804000:181584618158461816157312Staphylococcus aureus subsp. aureus N315, complete genomehypothetical protein8e-0649.3
NC_017351:1869287:188237118823711882682312Staphylococcus aureus subsp. aureus 11819-97 chromosome, completerhodanese-like domain-containing protein8e-0649.3
NC_010723:1014334:101628610162861016606321Clostridium botulinum E3 str. Alaska E43, complete genomeconserved protein YtwF8e-0648.9
NC_020210:2133996:2134851213485121359871137Geobacillus sp. GHH01, complete genomebeta-lactamase- and rhodanese-like protein9e-0648.9
NC_007622:1751500:176265117626511762962312Staphylococcus aureus RF122, complete genomehypothetical protein9e-0648.9
NC_020164:1037979:104351110435111043822312Staphylococcus warneri SG1, complete genomehypothetical protein9e-0648.9