Pre_GI: BLASTP Hits

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Query: NC_017265:854492:860210 Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,

Start: 860210, End: 861136, Length: 927

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017168:50391:561935619357119927Yersinia pestis A1122 chromosome, complete genomeglutaminase3e-169594
NC_005810:3964468:397018639701863971112927Yersinia pestis biovar Microtus str. 91001, complete genomeglutaminase3e-169594
NC_004088:3661601:367623336762333677159927Yersinia pestis KIM, complete genomeglutaminase3e-169594
NC_008149:3529428:354405935440593544985927Yersinia pestis Nepal516, complete genomeglutaminase3e-169594
NC_008150:361224:369061369061369987927Yersinia pestis Antiqua, complete genomeputative glutaminase3e-169594
NC_010159:138879:154831154831155757927Yersinia pestis Angola, complete genomeglutaminase3e-169594
NC_003143:1033500:104815510481551049081927Yersinia pestis CO92, complete genomeglutaminase3e-169594
NC_009381:627685:633402633402634328927Yersinia pestis Pestoides F chromosome, complete genomeglutaminase3e-169594
NC_014029:1001000:100677510067751007701927Yersinia pestis Z176003 chromosome, complete genomeglutaminase3e-169594
NC_017154:941065:948920948920949846927Yersinia pestis D106004 chromosome, complete genomeglutaminase3e-169594
NC_010634:3692321:370696037069603707886927Yersinia pseudotuberculosis PB1/+, complete genomeglutaminase, core1e-167588
NC_006155:3779381:379397837939783794904927Yersinia pseudotuberculosis IP 32953, complete genomeglutaminase1e-167588
NC_010465:933488:939299939299940225927Yersinia pseudotuberculosis YPIII, complete genomeGlutaminase1e-167588
NC_009708:986918:992835992835993761927Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeglutaminase4e-167587
NC_017160:945176:950951950951951820870Yersinia pestis D182038 chromosome, complete genomeglutaminase6e-158556
NC_016818:3851542:385230138523013853227927Rahnella aquatilis CIP 78.65 = ATCC 33071 chromosome, completeglutaminase A2e-132472
NC_015061:3840463:384046338404633841389927Rahnella sp. Y9602 chromosome, complete genomeGlutaminase, core6e-132470
NC_017047:3907854:390785439078543908780927Rahnella aquatilis HX2 chromosome, complete genomeglutaminase6e-132470
NC_012214:2019000:203569820356982036624927Erwinia pyrifoliae Ep1/96, complete genomeGlutaminase6e-132470
NC_013508:275081:297236297236298162927Edwardsiella tarda EIB202, complete genomeglutaminase1e-128459
NC_012779:261438:280262280262281188927Edwardsiella ictaluri 93-146, complete genomeglutaminase, putative2e-127455
NC_016902:2361628:237991523799152380841927Escherichia coli KO11FL chromosome, complete genomeglutaminase1e-126452
NC_008563:1651270:165127016512701652196927Escherichia coli APEC O1, complete genomeputative glutaminase1e-126452
NC_010498:1615980:163588216358821636808927Escherichia coli SMS-3-5, complete genomeglutaminase1e-126452
CP002516:2361628:237991523799152380841927Escherichia coli KO11, complete genomeGlutaminase, core1e-126452
NC_009778:1717458:175628917562891757215927Enterobacter sakazakii ATCC BAA-894, complete genomehypothetical protein2e-125449
NC_010067:1414000:142156814215681422548981Salmonella enterica subsp. arizonae serovar 62:z4,z23:--, completehypothetical protein2e-123441
NC_009792:1479779:149572614957261496640915Citrobacter koseri ATCC BAA-895, complete genomehypothetical protein4e-122437
NC_020418:1397112:142213814221381423088951Morganella morganii subsp. morganii KT, complete genomeGlutaminase1e-119429
NC_009654:4253431:427287042728704273781912Marinomonas sp. MWYL1, complete genomeglutaminase5e-90330
NC_010515:2449143:246439124643912465305915Burkholderia cenocepacia MC0-3 chromosome 2, complete sequenceGlutaminase5e-79294
NC_005085:4499500:450058045005804501494915Chromobacterium violaceum ATCC 12472, complete genomeglutaminase6e-78291
NC_014033:772754:772754772754773668915Prevotella ruminicola 23 chromosome, complete genomeglutaminase2e-66252
NC_019907:539749:569284569284570210927Liberibacter crescens BT-1 chromosome, complete genomeGlutaminase4e-66251
NC_021177:2309615:2310188231018823112521065Streptomyces fulvissimus DSM 40593, complete genomeGlutaminase 22e-65249
NC_013162:1130554:114581411458141146728915Capnocytophaga ochracea DSM 7271, complete genomeGlutaminase9e-65247
NC_013222:1898164:191124119112411912107867Robiginitalea biformata HTCC2501, complete genomeglutaminase2e-64246
NC_014910:1912552:193575119357511936677927Alicycliphilus denitrificans BC chromosome, complete genomeglutaminase, core3e-60232
NC_014915:2149884:215727521572752158204930Geobacillus sp. Y412MC52 chromosome, complete genomeGlutaminase, core2e-54213
NC_013411:3010000:301734430173443018270927Geobacillus sp. Y412MC61, complete genomeGlutaminase2e-54213
NC_008262:2169262:216926221692622170179918Clostridium perfringens SM101, complete genomeglutaminase1e-50199
NC_003366:2286083:228608322860832287000918Clostridium perfringens str. 13, complete genomeglutaminase1e-50199
NC_008261:2481500:249993924999392500856918Clostridium perfringens ATCC 13124, complete genomeglutaminase1e-50199
NC_016048:3667890:366945436694543670401948Oscillibacter valericigenes Sjm18-20, complete genomeglutaminase1e-47190
NC_003366:728859:733374733374734297924Clostridium perfringens str. 13, complete genomeglutaminase2e-46186
NC_008262:654000:658610658610659533924Clostridium perfringens SM101, complete genomeglutaminase2e-46186
NC_015519:2580310:260002926000292600931903Tepidanaerobacter sp. Re1 chromosome, complete genomeglutaminase3e-46186
NC_008261:676000:680740680740681663924Clostridium perfringens ATCC 13124, complete genomeglutaminase3e-46185
NC_009925:330470:334454334454335419966Acaryochloris marina MBIC11017, complete genomeglutaminase2e-45182
NC_010572:802269:8072158072158084981284Streptomyces griseus subsp. griseus NBRC 13350, complete genomeputative glutaminase3e-43176
NC_018524:5066720:5089511508951150907851275Nocardiopsis alba ATCC BAA-2165 chromosome, complete genomeglutaminase A7e-43174
NC_010718:304440:317499317499318425927Natranaerobius thermophilus JW/NM-WN-LF, complete genomeL-glutaminase9e-42170
NC_008601:168063:1867271867271882681542Francisella tularensis subsp. novicida U112, complete genomeglutaminase4e-38158
NC_009749:1825453:1825453182545318269821530Francisella tularensis subsp. holarctica FTA, complete genomeglutaminase liver isoform1e-37157
NC_008369:1830442:1830442183044218319831542Francisella tularensis subsp. holarctica OSU18, complete genomeglutaminase1e-37157
NC_007880:1830803:1830803183080318323441542Francisella tularensis subsp. holarctica, complete genomeL-glutaminase1e-37157
NC_008800:4013298:402965540296554030596942Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,glutaminase4e-37155
NC_015224:3892972:390692339069233907867945Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,glutaminase5e-37154
NC_017190:1465079:151419815141981514866669Bacillus amyloliquefaciens LL3 chromosome, complete genomeglutaminase1e-33144
NC_015673:1038673:1045329104532910466001272Corynebacterium resistens DSM 45100 chromosome, complete genomeglutaminase6e-34144
NC_009614:4802000:480204248020424803004963Bacteroides vulgatus ATCC 8482 chromosome, complete genomeglutaminase2e-33143
NC_007974:138176:152666152666153664999Ralstonia metallidurans CH34 chromosome 2, complete sequenceglutaminase4e-32138
NC_019771:4922140:492619149261914927096906Anabaena cylindrica PCC 7122, complete genomeL-glutaminase6e-30131
NC_013861:3659094:367522336752233676152930Legionella longbeachae NSW150, complete genomeglutaminase4e-27122
NC_009480:31412:336773367734654978Clavibacter michiganensis subsp. michiganensis NCPPB 382, completeputative glutaminase5e-27121
NC_017190:1465079:147030414703041470603300Bacillus amyloliquefaciens LL3 chromosome, complete genomeglutaminase1e-1584