Pre_GI: BLASTP Hits

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Query: NC_017265:2940539:2952057 Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,

Start: 2952057, End: 2952404, Length: 348

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017168:2535732:254605325460532546451399Yersinia pestis A1122 chromosome, complete genomehypothetical protein1e-40164
NC_004088:1510467:151806215180621518460399Yersinia pestis KIM, complete genomehypothetical protein1e-40164
NC_005810:3021913:303257230325723032970399Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein1e-40164
NC_008150:2574794:258513525851352585533399Yersinia pestis Antiqua, complete genomehypothetical protein1e-40164
NC_003143:3191246:320156732015673201965399Yersinia pestis CO92, complete genomehypothetical protein1e-40164
NC_008149:1440371:144798214479821448380399Yersinia pestis Nepal516, complete genomehypothetical protein1e-40164
NC_014029:3171627:317922231792223179620399Yersinia pestis Z176003 chromosome, complete genomehypothetical protein1e-40164
NC_017154:2876545:288681128868112887209399Yersinia pestis D106004 chromosome, complete genomehypothetical protein1e-40164
NC_009708:1403434:141045814104581410856399Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein3e-40163
NC_006155:3333303:334383133438313344229399Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein7e-37152
NC_008150:2574794:258421925842192584614396Yersinia pestis Antiqua, complete genomehypothetical protein1e-26118
NC_005810:3021913:303165630316563032051396Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein1e-26118
NC_004088:1510467:151898115189811519376396Yersinia pestis KIM, complete genomehypothetical protein1e-26118
NC_010465:1427170:143681414368141437209396Yersinia pseudotuberculosis YPIII, complete genomeprotein of unknown function DUF12401e-26118
NC_003143:3191246:320065132006513201046396Yersinia pestis CO92, complete genomehypothetical protein1e-26118
NC_008149:1440371:144890114489011449296396Yersinia pestis Nepal516, complete genomehypothetical protein1e-26118
NC_017168:2535732:254513725451372545532396Yersinia pestis A1122 chromosome, complete genomehypothetical protein1e-26118
NC_017265:2940539:295114129511412951536396Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein1e-26118
NC_006155:3333303:334291533429153343310396Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein2e-26117
NC_010634:3250810:326039932603993260794396Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein2e-26117
NC_010465:1427170:143589514358951436128234Yersinia pseudotuberculosis YPIII, complete genomehypothetical protein3e-25113
NC_010634:3250810:326085632608563261251396Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein4e-22103
NC_006155:3333303:334334833433483343767420Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein4e-22103
NC_010634:3250810:326148032614803261713234Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein6e-22102
NC_008150:2574794:258376025837602584155396Yersinia pestis Antiqua, complete genomehypothetical protein6e-2199.4
NC_003143:3191246:320019232001923200587396Yersinia pestis CO92, complete genomehypothetical protein6e-2199.4
NC_004088:1510467:151944015194401519835396Yersinia pestis KIM, complete genomehypothetical protein6e-2199.4
NC_010634:3250810:325994032599403260335396Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein6e-2199.4
NC_006155:3333303:334245633424563342851396Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein6e-2199.4
NC_010465:1427170:143727314372731437668396Yersinia pseudotuberculosis YPIII, complete genomeprotein of unknown function DUF12406e-2199.4
NC_014029:3171627:318060031806003180995396Yersinia pestis Z176003 chromosome, complete genomehypothetical protein6e-2199.4
NC_017154:2876545:288543628854362885831396Yersinia pestis D106004 chromosome, complete genomehypothetical protein6e-2199.4
NC_017168:2535732:254467825446782545073396Yersinia pestis A1122 chromosome, complete genomehypothetical protein6e-2199.4
NC_017265:2940539:295068229506822951077396Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein6e-2199.4
NC_005810:3021913:303096030309603031253294Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein4e-1993.2
NC_010465:1427170:143635714363571436752396Yersinia pseudotuberculosis YPIII, complete genomeprotein of unknown function DUF12402e-1684.7
NC_008150:2574794:258467625846762585071396Yersinia pestis Antiqua, complete genomehypothetical protein2e-1684.7
NC_004088:1510467:151852415185241518943420Yersinia pestis KIM, complete genomehypothetical protein1e-1684.7
NC_003143:3191246:320108432010843201503420Yersinia pestis CO92, complete genomehypothetical protein1e-1684.7
NC_008149:1440371:144844414484441448863420Yersinia pestis Nepal516, complete genomehypothetical protein1e-1684.7
NC_017168:2535732:254557025455702545989420Yersinia pestis A1122 chromosome, complete genomehypothetical protein1e-1684.7
NC_017265:2940539:295157429515742951993420Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein1e-1684.7
NC_005810:3021913:303208930320893032508420Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein4e-1683.2