Pre_GI: BLASTP Hits

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Query: NC_017265:2586729:2590148 Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,

Start: 2590148, End: 2591380, Length: 1233

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017168:3977767:3981186398118639824181233Yersinia pestis A1122 chromosome, complete genomehypothetical protein0792
NC_010465:2820500:2850642285064228518741233Yersinia pseudotuberculosis YPIII, complete genomehypothetical protein0789
NC_017060:125480:1388951388951401061212Rahnella aquatilis HX2 plasmid PRA1, complete sequencehypothetical protein4e-23109
NC_012721:240000:2558842558842571731290Burkholderia glumae BGR1 chromosome 2, complete genomehypothetical protein2e-1687.4
NC_004088:2966331:2969750296975029709821233Yersinia pestis KIM, complete genomehypothetical protein0792
NC_013956:4579759:4583241458324145844491209Pantoea ananatis LMG 20103 chromosome, complete genomehypothetical protein6e-73275
NC_010501:3575726:3583517358351735847491233Pseudomonas putida W619, complete genomehypothetical protein7e-46184
NC_016626:400080:4216234216234228761254Burkholderia sp. YI23 plasmid byi_1p, complete sequencehypothetical protein4e-1789.4
NC_009255:2044291:2050728205072820520171290Burkholderia vietnamiensis G4 chromosome 2, complete sequencehypothetical protein8e-0755.1
NC_008149:2802392:2805811280581128070431233Yersinia pestis Nepal516, complete genomehypothetical protein0792
NC_016612:4823529:4826996482699648282191224Klebsiella oxytoca KCTC 1686 chromosome, complete genomehypothetical protein2e-80299
NC_010067:2529750:2535370253537025365781209Salmonella enterica subsp. arizonae serovar 62:z4,z23:--, completehypothetical protein2e-1894.4
NC_007348:2011957:2024056202405620253841329Ralstonia eutropha JMP134 chromosome 2, complete sequencehypothetical protein3e-1066.6
NC_009381:1682000:1687080168708016883121233Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein0792
NC_009708:2788855:2824073282407328253051233Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein0788
NC_015062:130359:1420651420651432761212Rahnella sp. Y9602 plasmid pRAHAQ01, complete sequencehypothetical protein4e-23109
NC_013282:2026083:2049186204918620503941209Cronobacter turicensis, complete genomehypothetical protein1e-1377.8
NC_012731:2302974:2317254231725423184741221Klebsiella pneumoniae NTUH-K2044 chromosome, complete genomeputative structural protein3e-65249
NC_014121:1822895:1833664183366418348721209Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, completeputative structural protein2e-60233
NC_009648:1487692:1503939150393915051471209Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genomeputative structural protein9e-65247