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Query: NC_017265:1000342:1023772 Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,

Start: 1023772, End: 1024203, Length: 432

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_003143:875367:8819478819478835901644Yersinia pestis CO92, complete genomeputative methyl-accepting chemotaxis protein1e-67254
NC_006155:3596120:3602717360271736043601644Yersinia pseudotuberculosis IP 32953, complete genomeputative methyl-accepting chemotaxis protein.1e-67254
NC_010465:1118147:1142229114222911439201692Yersinia pseudotuberculosis YPIII, complete genomemethyl-accepting chemotaxis sensory transducer1e-67254
NC_010159:3448490:3456089345608934577801692Yersinia pestis Angola, complete genomemethyl-accepting chemotaxis protein2e-67254
NC_010634:3509880:3516477351647735181681692Yersinia pseudotuberculosis PB1/+, complete genomemethyl-accepting chemotaxis sensory transducer2e-67253
NC_004088:3505383:3511963351196335136631701Yersinia pestis KIM, complete genomemethyl-accepting chemotaxis protein2e-67253
NC_008149:3373229:3379809337980933815001692Yersinia pestis Nepal516, complete genomemethyl-accepting chemotaxis protein2e-67253
NC_008150:513783:5371615371615388521692Yersinia pestis Antiqua, complete genomeputative methyl-accepting chemotaxis protein2e-67253
NC_014029:1146900:1170279117027911719701692Yersinia pestis Z176003 chromosome, complete genomemethyl-accepting chemotaxis protein2e-67253
NC_017154:1089044:1112424111242411141151692Yersinia pestis D106004 chromosome, complete genomemethyl-accepting chemotaxis protein2e-67253
NC_017160:1092839:1115096111509611167871692Yersinia pestis D182038 chromosome, complete genomemethyl-accepting chemotaxis protein2e-67253
NC_017168:199381:2216442216442233351692Yersinia pestis A1122 chromosome, complete genomemethyl-accepting chemotaxis protein2e-67253
NC_005810:3142384:3167075316707531687751701Yersinia pestis biovar Microtus str. 91001, complete genomemethyl-accepting chemotaxis protein2e-67253
NC_009708:1131500:1153774115377411554651692Yersinia pseudotuberculosis IP 31758 chromosome, complete genomemethyl-accepting chemotaxis protein1e-66251
NC_008800:3642679:3650397365039736519381542Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,putative methyl-accepting chemotaxis protein2e-39160
NC_009778:1717458:1754648175464817562371590Enterobacter sakazakii ATCC BAA-894, complete genomehypothetical protein4e-1993.6
NC_009792:1479779:1496716149671614983051590Citrobacter koseri ATCC BAA-895, complete genomehypothetical protein1e-1685.1