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Query: NC_017265:1000342:1022455 Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,

Start: 1022455, End: 1023171, Length: 717

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017168:199381:220375220375221091717Yersinia pestis A1122 chromosome, complete genomeputative regulatory membrane protein3e-103374
NC_010159:3448490:345833334583333459049717Yersinia pestis Angola, complete genome3e-103374
NC_003143:875367:884191884191884907717Yersinia pestis CO92, complete genomeputative regulatory membrane protein3e-103374
NC_008149:3373229:338205333820533382769717Yersinia pestis Nepal516, complete genomeregulatory membrane protein3e-103374
NC_014029:1146900:116901011690101169726717Yersinia pestis Z176003 chromosome, complete genomeputative regulatory membrane protein3e-103374
NC_017154:1089044:111115511111551111871717Yersinia pestis D106004 chromosome, complete genomeputative regulatory membrane protein3e-103374
NC_017160:1092839:111382711138271114543717Yersinia pestis D182038 chromosome, complete genomeputative regulatory membrane protein3e-103374
NC_008150:513783:535893535893536642750Yersinia pestis Antiqua, complete genomeputative regulatory membrane protein9e-103372
NC_004088:3505383:351420735142073514911705Yersinia pestis KIM, complete genomehypothetical protein1e-100365
NC_010465:1118147:114095811409581141710753Yersinia pseudotuberculosis YPIII, complete genometranscriptional regulator, CadC2e-97355
NC_010634:3509880:351878135187813519440660Yersinia pseudotuberculosis PB1/+, complete genometranscriptional regulator, CadC2e-90332
NC_006155:3596120:360502136050213605680660Yersinia pseudotuberculosis IP 32953, complete genomeputative regulatory membrane protein.2e-90332
NC_009708:1131500:115250211525021153161660Yersinia pseudotuberculosis IP 31758 chromosome, complete genometranscriptional regulator7e-90330
NC_015224:1067390:108967810896781090337660Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,transcriptional regulator, CadC3e-39162
NC_008800:3642679:365260736526073653266660Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,reguatory protein9e-38157
NC_010694:2138000:217087921708792171457579Erwinia tasmaniensis, complete genomehypothetical protein1e-1067
NC_012214:2221702:225819822581982258842645Erwinia pyrifoliae Ep1/96, complete genomehypothetical protein1e-0860.1
NC_013971:1660144:166986616698661670465600Erwinia amylovora ATCC 49946 chromosome, complete genometranscriptional regulator3e-0858.9
NC_013961:1622616:163233816323381632937600Erwinia amylovora, complete genomeTranscriptional regulatory protein glnR3e-0858.9
NC_017249:60216:7104371043726741632Bradyrhizobium japonicum USDA 6, complete genomehypothetical protein3e-0755.5
NC_020541:3156500:3165653316565331683102658Rhodanobacter sp. 2APBS1, complete genometranscriptional regulatory protein,protein kinase family protein1e-0653.1