Pre_GI: BLASTP Hits

Some Help

Query: NC_017265:1000342:1021866 Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,

Start: 1021866, End: 1022171, Length: 306

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017160:1092839:111323811132381113543306Yersinia pestis D182038 chromosome, complete genomeputative lipoprotein6e-51199
NC_017154:1089044:111056611105661110871306Yersinia pestis D106004 chromosome, complete genomeputative lipoprotein6e-51199
NC_014029:1146900:116842111684211168726306Yersinia pestis Z176003 chromosome, complete genomeputative lipoprotein6e-51199
NC_008149:3373229:338305333830533383358306Yersinia pestis Nepal516, complete genomelipoprotein6e-51199
NC_008150:513783:535304535304535609306Yersinia pestis Antiqua, complete genomeputative lipoprotein6e-51199
NC_003143:875367:885191885191885496306Yersinia pestis CO92, complete genomeputative lipoprotein6e-51199
NC_004088:3505383:351520735152073515527321Yersinia pestis KIM, complete genomehypothetical protein3e-49193
NC_017168:199381:219771219771220091321Yersinia pestis A1122 chromosome, complete genomehypothetical protein3e-49193
NC_009381:775357:795685795685796050366Yersinia pestis Pestoides F chromosome, complete genomelipoprotein2e-48191
NC_005810:3142384:316384331638433164208366Yersinia pestis biovar Microtus str. 91001, complete genomeputative lipoprotein2e-48191
NC_010634:3509880:351972435197243520089366Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein2e-48191
NC_006155:3596120:360596436059643606329366Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein2e-48191
NC_010465:1118147:114030911403091140674366Yersinia pseudotuberculosis YPIII, complete genomeputative lipoprotein2e-48191
NC_010159:3448490:345933334593333459698366Yersinia pestis Angola, complete genome2e-48191
NC_009708:1131500:115185111518511152216366Yersinia pseudotuberculosis IP 31758 chromosome, complete genomelipoprotein7e-48188