Pre_GI: BLASTP Hits

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Query: NC_017200:4240500:4245214 Bacillus thuringiensis serovar finitimus YBT-020 chromosome,

Start: 4245214, End: 4248096, Length: 2883

Host Lineage: Bacillus thuringiensis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This organism, also known as BT, is famous for the production of an insecticidal toxin. The bacterium was initially discovered as a pathogen of various insects and was first used as an insecticidal agent in the early part of this century. This organism, like many other Bacilli, is found in the soil, where it leads a saprophytic existence, but becomes an opportunistic pathogen of insects when ingested. The specific activity of the toxin towards insects and its lack of toxicity to animals has made this organism a useful biocontrol agent. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The presence of a parasporal crystal, which is outside the exosporium of the endospore, is indicative of production of the toxin, and serves as a marker for this species.Activation of the toxin typically requires a high pH environment such as the alkaline environments in insect midguts followed by proteolysis.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_004557:2475030:249312024931202493731612Clostridium tetani E88, complete genometransporter2e-0655.1
NC_014366:588347:590654590654591514861Gamma proteobacterium HdN1, complete genomehypothetical protein2e-0655.5
NC_014448:414784:4386384386384396721035Mycoplasma hyorhinis HUB-1 chromosome, complete genomeVariant surface antigen A6e-0963.5