Pre_GI: BLASTP Hits

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Query: NC_017179:3222015:3222015 Clostridium difficile BI1, complete genome

Start: 3222015, End: 3223160, Length: 1146

Host Lineage: Peptoclostridium difficile; Peptoclostridium; Peptostreptococcaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium difficile BI1 is a human strain isolated in the United States in 1988. This species is now recognized as the major causative agent of pseudomembranous colitis (inflammation of the colon) and diarrhea that may occur following antibiotic treatment. C. difficile infection represents one of the most common nosocomial (originating in a hospital) infections. This bacterium causes a wide spectrum of disease, ranging from mild, self-limiting diarrhea to serious diarrhea and, in some cases, complications such as pseudomembrane formation, toxic megacolon (dilation of the colon) and peritonitis, which often lead to lethality among patients. The bacteria produce high molecular mass polypeptide cytotoxins, A and B. Some strains produce only one of the toxins, others produce both. Toxin A causes inflammatory reaction involving hypersecretion of fluid and hemorrhagic necrosis through triggering cytokine release by neutrophils. Cytotoxin B depolymerizes actin, the major protein of the cytoskeleton, and thus aids in destruction of tissues. The combined action of the toxins results in necrosis of superficial epithelium and edema (fluidic swelling) in affected areas of intestine. Proliferation of C. difficile is normally prevented by normal intestinal microflora, which is believed to inhibit attachment of the bacterium and its toxins to intestinal walls. Alteration of intestinal microbial balance with antibiotic therapy and increased exposure to the bacterium in a hospital setting allows C. difficile to colonize susceptible individuals. Moreover, it has been shown that subinhibitory concentrations of antibiotics promote increased toxin production by C. difficile.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_013315:3214063:3214063321406332152081146Clostridium difficile CD196 chromosome, complete genomesignaling protein0649
NC_015977:2807782:2842047284204728436451599Roseburia hominis A2-183 chromosome, complete genometwo-component system PleD-like family response regulator6e-1685.5
NC_010424:448865:4576744576744602352562Candidatus Desulforudis audaxviator MP104C, complete genomediguanylate cyclase with PAS/PAC sensor9e-1271.6
NC_012559:2752825:2754370275437027565922223Laribacter hongkongensis HLHK9, complete genomePredicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain4e-1169.7
NC_017192:1841987:1849192184919218504961305Arcobacter sp. L, complete genomediguanylate cyclase6e-1168.9
NC_009699:1352211:1366099136609913673581260Clostridium botulinum F str. Langeland chromosome, complete genomesensory box-containing diguanylate cyclase2e-1067
NC_017297:1352506:1366393136639313676521260Clostridium botulinum F str. 230613 chromosome, complete genomeputative sensory box-containing diguanylate cyclase2e-1067
NC_011663:1867000:1872155187215518763874233Shewanella baltica OS223 chromosome, complete genomePAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase1e-0964.7
NC_012796:1049034:1093541109354110954151875Desulfovibrio magneticus RS-1, complete genomeputative signaling protein1e-0964.7
NC_014654:221707:2364332364332389612529Halanaerobium sp. 'sapolanicus' chromosome, complete genomediguanylate cyclase with PAS/PAC sensor2e-0964.3
NC_019673:6778401:6787778678777867893191542Saccharothrix espanaensis DSM 44229 complete genomeputative diguanylate cyclase1e-0964.3
NC_009052:3229775:3237627323762732418864260Shewanella baltica OS155, complete genomediguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s)1e-0964.3
NC_016646:275818:2773222773222790101689Pseudovibrio sp. FO-BEG1 plasmid unnamed, complete sequencesensory box/GGDEF/EAL family protein1e-0964.3
NC_014632:567289:5672895672895686861398Ilyobacter polytropus DSM 2926 chromosome, complete genomediguanylate cyclase2e-0963.9
NC_009468:38112:514045140452369966Acidiphilium cryptum JF-5 plasmid pACRY02, complete sequencediguanylate cyclase2e-0963.5
NC_012796:1049034:1061214106121410631031890Desulfovibrio magneticus RS-1, complete genomeputative signaling protein2e-0963.5
NC_015690:1772015:1798174179817417997091536Paenibacillus mucilaginosus KNP414 chromosome, complete genomePAS/PAC sensor-containing diguanylate cyclase2e-0963.5
NC_012483:483425:5114635114635125661104Acidobacterium capsulatum ATCC 51196, complete genomeGGDEF domain protein3e-0963.2
NC_016614:822715:839152839152840123972Vibrio sp. EJY3 chromosome 2, complete sequencediguanylate cyclase/phosphodiesterase domain 25e-0962.4
NC_015593:2696000:2714665271466527168332169Sphingobium chlorophenolicum L-1 chromosome chromosome 1, completeresponse regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)7e-0962
NC_014328:3120145:313375831337583134501744Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative GGDEF domain-containing protein7e-0962
NC_014654:302000:314699314699315589891Halanaerobium sp. 'sapolanicus' chromosome, complete genomediguanylate cyclase with PAS/PAC sensor6e-0962
NC_008702:2942246:2960329296032929624042076Azoarcus sp. BH72, complete genomeGGDEF/EAL/PAS-domain containing protein8e-0961.6
NC_010551:1412139:1426967142696714282111245Burkholderia ambifaria MC40-6 chromosome 1, complete sequencediguanylate cyclase with GAF sensor1e-0861.6
NC_016935:2302055:2328336232833623298711536Paenibacillus mucilaginosus 3016 chromosome, complete genomePAS/PAC sensor-containing diguanylate cyclase1e-0861.6
NC_018697:618832:6389586389586433854428Cycloclasticus sp. P1 chromosome, complete genomeresponse regulator receiver modulated diguanylate cyclase/phosphodiesterase1e-0861.2
NC_011661:203929:2047552047552061521398Dictyoglomus turgidum DSM 6724, complete genomediguanylate cyclase and metal dependent phosphohydrolase1e-0861.2
NC_015497:1058980:1077978107797810800322055Glaciecola agarilytica 4H-3-7+YE-5 chromosome, complete genomediguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)1e-0861.2
NC_012796:4075583:4187469418746941885991131Desulfovibrio magneticus RS-1, complete genomeGGDEF domain protein2e-0860.8
NC_009663:851143:8714898714898737562268Sulfurovum sp. NBC37-1, complete genomesignal transduction response regulator2e-0860.8
NC_004578:568236:5861005861005885892490Pseudomonas syringae pv. tomato str. DC3000, complete genomesensory box/GGDEF domain/EAL domain protein2e-0860.8
NC_010002:3785313:3804112380411238052931182Delftia acidovorans SPH-1, complete genomediguanylate cyclase2e-0860.5
NC_012912:1229333:1238015123801512395321518Dickeya zeae Ech1591, complete genomediguanylate cyclase with PAS/PAC and GAF sensors2e-0860.5
NC_015949:1887478:1908054190805419097301677Caldicellulosiruptor lactoaceticus 6A chromosome, complete genomediguanylate cyclase2e-0860.5
NC_012440:1080675:1080675108067510819671293Persephonella marina EX-H1, complete genomesignal transduction response regulator2e-0860.1
NC_014376:2964731:2978427297842729811832757Clostridium saccharolyticum WM1 chromosome, complete genomediguanylate cyclase and metal dependent phosphohydrolase3e-0860.1
NC_015563:3786192:3788095378809537892761182Delftia sp. Cs1-4 chromosome, complete genomediguanylate cyclase3e-0860.1
NC_008786:3291700:3305661330566133074991839Verminephrobacter eiseniae EF01-2, complete genomediguanylate cyclase3e-0860.1
NC_007759:964000:971072971072971956885Syntrophus aciditrophicus SB, complete genomesensory box/GGDEF family protein4e-0859.7
NC_008322:1708631:1714777171477717190694293Shewanella sp. MR-7, complete genomediguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)4e-0859.7
NC_008321:1636148:1643414164341416477064293Shewanella sp. MR-4, complete genomediguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)4e-0859.7
NC_007005:5500196:5504338550433855068242487Pseudomonas syringae pv. syringae B728a, complete genomePAS:GGDEF3e-0859.7
NC_012115:1415827:143229314322931433264972Nautilia profundicola AmH, complete genomeggdef domain protein3e-0859.7
NC_012667:703852:7087997087997107271929Vibrio cholerae MJ-1236 chromosome 2, complete genomesensory box/GGDEF family protein3e-0859.7
NC_009663:1237336:1237767123776712389961230Sulfurovum sp. NBC37-1, complete genomesignal transduction response regulator3e-0859.7
NC_015942:447308:4638614638614664882628Acidithiobacillus ferrivorans SS3 chromosome, complete genomediguanylate cyclase/phosphodiesterase4e-0859.3
NC_012880:3241886:3247481324748132490011521Dickeya dadantii Ech703, complete genomediguanylate cyclase with PAS/PAC and GAF sensors6e-0858.9
NC_014387:1106901:1119903111990311214111509Butyrivibrio proteoclasticus B316 chromosome 1, complete genomeGGDEF domain-containing protein6e-0858.9
NC_015185:485866:4890684890684907111644Desulfurobacterium thermolithotrophum DSM 11699 chromosome,diguanylate cyclase6e-0858.9
NC_015172:1161000:1174036117403611766122577Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomediguanylate cyclase and metal dependent phosphohydrolase5e-0858.9
NC_011978:699500:715625715625716464840Thermotoga neapolitana DSM 4359, complete genomeDiguanylate cyclase9e-0858.5
NC_015161:36668:4282342823461953373Deinococcus proteolyticus MRP chromosome, complete genome8e-0858.5
AC_000091:2027648:2028460202846020301541695Escherichia coli W3110 DNA, complete genomepredicted diguanylate cyclase8e-0858.5
NC_012947:1769438:1809320180932018110141695Escherichia coli 'BL21-Gold(DE3)pLysS AG' chromosome, completediguanylate cyclase8e-0858.5
NC_014614:2500301:2501884250188425033921509Clostridium sticklandii, complete genomePutative sensory box-containing diguanylate cyclase (fragment)8e-0858.5
NC_008577:1690946:1698103169810317024044302Shewanella sp. ANA-3 chromosome 1, complete sequencediguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)8e-0858.5
NC_008576:3331825:3339175333917533425313357Magnetococcus sp. MC-1, complete genomediguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s)8e-0858.5
NC_013216:4131563:4133631413363141350551425Desulfotomaculum acetoxidans DSM 771, complete genomediguanylate cyclase and metal dependent phosphohydrolase8e-0858.5
NC_014328:1596016:1604491160449116069712481Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative transport/signal transduction system protein7e-0858.5
NC_010498:1210145:1231371123137112330471677Escherichia coli SMS-3-5, complete genomediguanylate cyclase7e-0858.5
NC_013959:1555799:1567917156791715696291713Sideroxydans lithotrophicus ES-1 chromosome, complete genomeperiplasmic/7TM domain sensor diguanylate cyclase7e-0858.5
NC_008340:1303607:1305923130592313074071485Alkalilimnicola ehrlichei MLHE-1, complete genomediguanylate cyclase with PAS/PAC sensor7e-0858.5
NC_010125:3771910:3782214378221437851382925Gluconacetobacter diazotrophicus PAl 5, complete genomeputative signalling protein, GGDEF family1e-0758.2
NC_010163:145808:1631041631041642311128Acholeplasma laidlawii PG-8A chromosome, complete genomeGGDEF domain-containing protein1e-0758.2
NC_009649:94871:107129107129108085957Klebsiella pneumoniae subsp. pneumoniae MGH 78578 plasmid pKPN3,hypothetical protein1e-0758.2
NC_016822:2201388:2202200220220022038941695Shigella sonnei 53G, complete genomediguanylate cyclase1e-0758.2
NC_015276:1426000:1442951144295114442311281Marinomonas mediterranea MMB-1 chromosome, complete genomediguanylate cyclase9e-0858.2
NC_014121:398012:4109994109994122461248Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, completediguanylate cyclase with PAS/PAC sensor1e-0757.8
NC_016745:1548426:1551071155107115526421572Oceanimonas sp. GK1 chromosome, complete genomediguanylate cyclase1e-0757.8
NC_015690:7518732:7534888753488875366271740Paenibacillus mucilaginosus KNP414 chromosome, complete genomeresponse regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)1e-0757.8
NC_016027:1647110:1663782166378216660402259Gluconacetobacter xylinus NBRC 3288, complete genomec-di-GMP phosphodiesterase A1e-0757.8
NC_015873:450593:4511354511354558234689Megasphaera elsdenii DSM 20460, complete genomediguanylate cyclase/phosphodiesterase1e-0757.8
NC_011126:1345984:1364891136489113660211131Hydrogenobaculum sp. Y04AAS1, complete genomediguanylate cyclase2e-0757.4
NC_015557:1333158:1354921135492113560241104Hydrogenobaculum sp. 3684 chromosome, complete genomediguanylate cyclase2e-0757.4
NC_020411:1333352:1355115135511513562181104Hydrogenobaculum sp. HO, complete genomediguanylate cyclase2e-0757.4
NC_014387:2297304:2297304229730422986771374Butyrivibrio proteoclasticus B316 chromosome 1, complete genomeGGDEF/PAS domain-containing protein2e-0757.4
NC_010506:1893000:1900209190020919020771869Shewanella woodyi ATCC 51908, complete genomediguanylate cyclase2e-0757.4
NC_009778:1717458:1757701175770117591431443Enterobacter sakazakii ATCC BAA-894, complete genomehypothetical protein3e-0757
NC_007520:407627:4287244287244303461623Thiomicrospira crunogena XCL-2, complete genomediguanylate cyclase (GGDEF domain) with PAS/PAC sensor3e-0757
NC_008435:2658986:2706620270662027086202001Rhodopseudomonas palustris BisA53, complete genomediguanylate cyclase/phosphodiesterase2e-0757
NC_012796:4075583:4132662413266241336931032Desulfovibrio magneticus RS-1, complete genomeGGDEF domain protein2e-0757
NC_015850:169180:1953721953721974172046Acidithiobacillus caldus SM-1 chromosome, complete genomePAS/PAC and GAF sensor-containing diguanylate cyclase/phosphodiesterase2e-0757
NC_014624:551510:5952225952225966911470Eubacterium limosum KIST612 chromosome, complete genomehypothetical protein2e-0757
NC_010475:1563578:1580953158095315825121560Synechococcus sp. PCC 7002, complete genomeGGDEF domain protein2e-0757
NC_010625:1551430:156081215608121561420609Burkholderia phymatum STM815 plasmid pBPHY01, complete sequencediguanylate cyclase2e-0757
NC_010730:1519458:1524413152441315256481236Sulfurihydrogenibium sp. YO3AOP1, complete genomediguanylate cyclase3e-0756.6
NC_014152:397177:413984413984414652669Thermincola sp. JR, complete genomediguanylate cyclase3e-0756.6
NC_014910:4207227:4224497422449742272622766Alicycliphilus denitrificans BC chromosome, complete genomediguanylate cyclase3e-0756.6
NC_011186:819828:8415748415748430071434Vibrio fischeri MJ11 chromosome II, complete sequenceggdef domain protein3e-0756.6
NC_009138:467268:497408497408498184777Herminiimonas arsenicoxydans, complete genomeputative signaling protein3e-0756.6
NC_009512:469000:4821324821324858753744Pseudomonas putida F1, complete genomediguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s)3e-0756.2
NC_006138:2630338:2642868264286826448501983Desulfotalea psychrophila LSv54, complete genomehypothetical protein4e-0756.2
NC_015559:2434000:2450680245068024519331254Marinomonas posidonica IVIA-Po-181 chromosome, complete genomediguanylate cyclase4e-0756.2
NC_013166:82986:1085441085441097251182Kangiella koreensis DSM 16069, complete genomediguanylate cyclase6e-0755.8
NC_016633:289500:2971592971592987451587Sphaerochaeta pleomorpha str. Grapes chromosome, complete genomediguanylate cyclase domain-containing protein5e-0755.8
NC_014618:2788533:2788533278853327895401008Enterobacter cloacae SCF1 chromosome, complete genomeGAF sensor-containing diguanylate cyclase5e-0755.8
NC_008700:3514745:3535999353599935376721674Shewanella amazonensis SB2B, complete genomeputative diguanylate cyclase (GGDEF domain protein)5e-0755.8
NC_009674:3863667:3882930388293038856502721Bacillus cytotoxicus NVH 391-98 chromosome, complete genomePAS/PAC and GAF sensor-containing diguanylate cyclase/phosphodiesterase5e-0755.8
NC_008027:2331617:2347081234708123481271047Pseudomonas entomophila L48, complete genomediguanylate cyclase (GGDEF domain)5e-0755.8
NC_009253:389835:4114594114594136992241Desulfotomaculum reducens MI-1 chromosome, complete genomePAS/PAC sensor-containing diguanylate cyclase6e-0755.5
NC_014633:583858:587751587751588692942Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequencediguanylate cyclase1e-0655.1
NC_015733:443122:4535964535964573393744Pseudomonas putida S16 chromosome, complete genomePAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase9e-0755.1
NC_007644:711476:7182737182737207832511Moorella thermoacetica ATCC 39073, complete genomeputative PAS/PAC sensor protein8e-0755.1
NC_012026:415447:4279314279314292981368Anaplasma marginale str. Florida, complete genomePutative two-component response regulator with GGDEF and receiver domains8e-0755.1
NC_009659:1050532:108753810875381088500963Janthinobacterium sp. Marseille chromosome, complete genomediguanylate cyclase8e-0755.1
NC_012880:2480000:2490854249085424927071854Dickeya dadantii Ech703, complete genomediguanylate cyclase with PAS/PAC and GAF sensors8e-0755.1
NC_014624:551510:5756525756525776822031Eubacterium limosum KIST612 chromosome, complete genomesensory box sensor/GGDEF/EAL domain protein8e-0755.1
NC_006841:750000:7687587687587700771320Vibrio fischeri ES114 chromosome II, complete sequencehypothetical protein8e-0755.1
NC_010676:3009980:3040903304090330440163114Burkholderia phytofirmans PsJN chromosome 2, complete sequencediguanylate cyclase/phosphodiesterase with PAS/PAC and Chase sensor(s)8e-0755.1
NC_006510:1501487:1503000150300015051502151Geobacillus kaustophilus HTA426, complete genomehypothetical protein8e-0755.1
NC_014388:55903:5808358083598071725Butyrivibrio proteoclasticus B316 chromosome 2, complete genomemethyl-accepting chemotaxis protein McpD1e-0654.7
NC_010718:2337209:2339430233943023407341305Natranaerobius thermophilus JW/NM-WN-LF, complete genomediguanylate cyclase and metal dependent phosphohydrolase1e-0654.7
NC_016514:891772:9260869260869278701785Enterobacter cloacae EcWSU1 chromosome, complete genomediguanylate cyclase DosC1e-0654.7
NC_014634:28690:460384603846904867Ilyobacter polytropus DSM 2926 plasmid pILYOP02, complete sequencediguanylate cyclase1e-0654.7
NC_009654:1729159:174077917407791741657879Marinomonas sp. MWYL1, complete genomediguanylate cyclase with PAS/PAC sensor1e-0654.7
NC_015573:893862:909972909972910757786Desulfotomaculum kuznetsovii DSM 6115 chromosome, complete genomediguanylate cyclase1e-0654.7
NC_012483:848750:8658848658848683042421Acidobacterium capsulatum ATCC 51196, complete genomecyclic diguanylate phosphodiesterase/diguanylate cyclase2e-0654.3
NC_009253:829913:8340778340778356391563Desulfotomaculum reducens MI-1 chromosome, complete genomePAS/PAC sensor-containing diguanylate cyclase2e-0654.3
NC_007086:1224867:1250567125056712515921026Xanthomonas campestris pv. campestris str. 8004, complete genomehypothetical protein2e-0654.3
NC_003902:3666544:3696204369620436972291026Xanthomonas campestris pv. campestris str. ATCC 33913, completehypothetical protein2e-0654.3
NC_014484:52311:837868378684682897Spirochaeta thermophila DSM 6192 chromosome, complete genomehypothetical protein1e-0654.3
NC_009784:253852:2538522538522561792328Vibrio harveyi ATCC BAA-1116 chromosome II, complete sequencehypothetical protein1e-0654.3
NC_010410:513298:5173925173925186151224Acinetobacter baumannii AYE, complete genomeconserved hypothetical protein; putative exported protein1e-0654.3
NC_008027:2996947:3002939300293930050292091Pseudomonas entomophila L48, complete genomediguanylate cyclase/phosphodiesterase (GGDEF & EAL domains)1e-0654.3
NC_021184:3533500:3538803353880335414452643Desulfotomaculum gibsoniae DSM 7213, complete genomePAS domain S-box/diguanylate cyclase (GGDEF) domain-containing protein2e-0653.9
NC_010611:3381500:3394142339414233952421101Acinetobacter baumannii ACICU, complete genomeGGDEF domain protein2e-0653.9
NC_013173:1671288:1676285167628516772921008Desulfomicrobium baculatum DSM 4028, complete genomeresponse regulator receiver modulated diguanylate cyclase2e-0653.9
NC_008463:632869:6433476433476470843738Pseudomonas aeruginosa UCBPP-PA14, complete genomehypothetical protein2e-0653.9
NC_004347:791897:808860808860809771912Shewanella oneidensis MR-1, complete genomeGGDEF family protein2e-0653.9
NC_012968:1191037:1199115119911512005601446Methylotenera mobilis JLW8, complete genomediguanylate cyclase with PAS/PAC and GAF sensors2e-0653.9
NC_004347:3197219:3205035320503532093034269Shewanella oneidensis MR-1, complete genomesensory box protein2e-0653.9
NC_011283:3379181:3391350339135033924081059Klebsiella pneumoniae 342 chromosome, complete genomeMASE2 domain/diguanylate cyclase2e-0653.9
NC_007645:2408125:2426051242605124280451995Hahella chejuensis KCTC 2396, complete genomeFOG: GGDEF domain2e-0653.9
NC_014121:3776902:3793829379382937952081380Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, completeputative diguanylate cyclase2e-0653.9
NC_008573:195317:220472220472221449978Shewanella sp. ANA-3 plasmid 1, complete sequencediguanylate cyclase with GAF sensor3e-0653.5
NC_009138:1843998:1882878188287818844521575Herminiimonas arsenicoxydans, complete genomehypothetical protein3e-0653.5
NC_014733:1573171:1596972159697215984681497Methylovorus sp. MP688 chromosome, complete genomediguanylate cyclase with pas/pac sensor3e-0653.5
NC_014829:4565467:4571843457184345745032661Bacillus cellulosilyticus DSM 2522 chromosome, complete genomediguanylate cyclase/phosphodiesterase3e-0653.5
NC_008800:1942000:1961046196104619631212076Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,hypothetical protein3e-0653.5
NC_020063:2565605:2576060257606025778681809Enterobacteriaceae bacterium strain FGI 57, complete genomediguanylate cyclase (GGDEF) domain-containing protein2e-0653.5
NC_016822:1431200:1431746143174614331341389Shigella sonnei 53G, complete genomediguanylate cyclase2e-0653.5
NC_006511:1243817:1243817124381712457991983Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCChypothetical protein2e-0653.5
NC_008262:1950205:195678719567871957656870Clostridium perfringens SM101, complete genomeresponse regulatory protein (sensory transduction system)2e-0653.5
NC_015554:4648919:4655328465532846572681941Alteromonas sp. SN2 chromosome, complete genomediguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s)4e-0653.1
NC_015977:2807782:2839324283932428412401917Roseburia hominis A2-183 chromosome, complete genomearabinogalactan endo-1,4-beta-galactosidase3e-0653.1
NC_010424:697187:731288731288732082795Candidatus Desulforudis audaxviator MP104C, complete genomediguanylate cyclase3e-0653.1
NC_021171:608315:6109966109966135182523Bacillus sp. 1NLA3E, complete genomePAS/PAC and GAF sensor-containing diguanylate cyclase/phosphodiesterase3e-0653.1
NC_012438:1211940:1225711122571112281912481Sulfurihydrogenibium azorense Az-Fu1 chromosome, complete genomeggdef domain protein3e-0653.1
NC_010506:1893000:1902176190217619041041929Shewanella woodyi ATCC 51908, complete genomediguanylate cyclase3e-0653.1
NC_015424:2316228:232358323235832324449867Aeromonas veronii B565 chromosome, complete genomesensory box/GGDEF family protein3e-0653.1
NC_014171:5107956:5123295512329551260242730Bacillus thuringiensis BMB171 chromosome, complete genomesensory box/GGDEF family protein5e-0652.8
NC_016810:2027311:2027311202731120290231713Salmonella enterica subsp. enterica serovar Typhimurium strhypothetical protein4e-0652.8
NC_016857:2027311:2027311202731120290231713Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74putative inner membrane protein4e-0652.8
NC_016863:2029340:2029340202934020310521713Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1putative inner membrane protein4e-0652.8
NC_017046:2026672:2026672202667220283841713Salmonella enterica subsp. enterica serovar Typhimurium str. 798hypothetical protein4e-0652.8
NC_011205:1227373:1247643124764312493551713Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853cellulose synthesis regulatory protein4e-0652.8
NC_015497:3614817:3637967363796736400572091Glaciecola agarilytica 4H-3-7+YE-5 chromosome, complete genomediguanylate cyclase/phosphodiesterase with extracellular sensor4e-0652.8
NC_014935:1223817:1235011123501112373502340Nitratifractor saLSUginis DSM 16511 chromosome, complete genomediguanylate cyclase/phosphodiesterase with pas/pac sensor(s)6e-0652.4
NC_014376:3064787:307990030799003080784885Clostridium saccharolyticum WM1 chromosome, complete genome6e-0652.4
NC_014654:422013:4220134220134255613549Halanaerobium sp. 'sapolanicus' chromosome, complete genomediguanylate cyclase and metal dependent phosphohydrolase5e-0652.4
NC_018697:618832:6313456313456328561512Cycloclasticus sp. P1 chromosome, complete genomeDiguanylate cyclase with PAS/PAC sensor and hemerythrin-like metal-binding domain5e-0652.4
NC_012912:4737703:4747041474704147493562316Dickeya zeae Ech1591, complete genomediguanylate cyclase with PAS/PAC and GAF sensors8e-0652
NC_012969:1574330:1598034159803415995451512Methylovorus glucosetrophus SIP3-4 chromosome, complete genomePAS/PAC sensor-containing diguanylate cyclase8e-0652
NC_016112:562570:5625705625705642971728Methylomicrobium alcaliphilum chromosome, complete genomeresponse regulator receiver modulated diguanylate cyclase/phosphodiesterase7e-0652
NC_017208:5273500:5286525528652552892542730Bacillus thuringiensis serovar chinensis CT-43 chromosome, completesensory box/GGDEF family protein7e-0652
NC_004722:5194000:5211310521131052140392730Bacillus cereus ATCC 14579, complete genomeSensory box/GGDEF family protein7e-0652
NC_010718:2551000:2576468257646825783391872Natranaerobius thermophilus JW/NM-WN-LF, complete genomediguanylate cyclase and metal dependent phosphohydrolase7e-0652
NC_011725:5201995:5219282521928252220112730Bacillus cereus B4264 chromosome, complete genomesensory box/GGDEF family protein7e-0652
NC_000913:1087062:1092099109209910934571359Escherichia coli K12, complete genomepredicted diguanylate cyclase8e-0651.6
NC_014500:4883794:4892448489244848947692322Dickeya dadantii 3937 chromosome, complete genomesensory box protein8e-0651.6
NC_016612:3843358:385819138581913859039849Klebsiella oxytoca KCTC 1686 chromosome, complete genomeMASE2 domain/diguanylate cyclase9e-0651.6
AC_000091:1083798:1093298109329810946561359Escherichia coli W3110 DNA, complete genomepredicted diguanylate cyclase9e-0651.6
NC_010468:2809125:2815497281549728168551359Escherichia coli ATCC 8739, complete genomediguanylate cyclase9e-0651.6
NC_010334:2615260:2623416262341626247201305Shewanella halifaxensis HAW-EB4, complete genomediguanylate cyclase1e-0551.6