Pre_GI: BLASTP Hits

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Query: NC_017179:1133510:1144061 Clostridium difficile BI1, complete genome

Start: 1144061, End: 1144963, Length: 903

Host Lineage: Peptoclostridium difficile; Peptoclostridium; Peptostreptococcaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium difficile BI1 is a human strain isolated in the United States in 1988. This species is now recognized as the major causative agent of pseudomembranous colitis (inflammation of the colon) and diarrhea that may occur following antibiotic treatment. C. difficile infection represents one of the most common nosocomial (originating in a hospital) infections. This bacterium causes a wide spectrum of disease, ranging from mild, self-limiting diarrhea to serious diarrhea and, in some cases, complications such as pseudomembrane formation, toxic megacolon (dilation of the colon) and peritonitis, which often lead to lethality among patients. The bacteria produce high molecular mass polypeptide cytotoxins, A and B. Some strains produce only one of the toxins, others produce both. Toxin A causes inflammatory reaction involving hypersecretion of fluid and hemorrhagic necrosis through triggering cytokine release by neutrophils. Cytotoxin B depolymerizes actin, the major protein of the cytoskeleton, and thus aids in destruction of tissues. The combined action of the toxins results in necrosis of superficial epithelium and edema (fluidic swelling) in affected areas of intestine. Proliferation of C. difficile is normally prevented by normal intestinal microflora, which is believed to inhibit attachment of the bacterium and its toxins to intestinal walls. Alteration of intestinal microbial balance with antibiotic therapy and increased exposure to the bacterium in a hospital setting allows C. difficile to colonize susceptible individuals. Moreover, it has been shown that subinhibitory concentrations of antibiotics promote increased toxin production by C. difficile.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_013315:1123733:113434111343411135186846Clostridium difficile CD196 chromosome, complete genomepseudouridylate synthase8e-162569
NC_011898:702983:705182705182706096915Clostridium cellulolyticum H10, complete genomepseudouridine synthase, RluA family1e-54213
NC_018515:3959681:397556839755683976539972Desulfosporosinus meridiei DSM 13257 chromosome, complete genomeribosomal large subunit pseudouridine synthase D1e-53210
NC_016012:396910:403771403771404670900Candidatus Arthromitus sp. SFB-rat-Yit, complete genomepseudouridine synthase, RluA family3e-53208
NC_016751:1700164:170744917074491708372924Marinitoga piezophila KA3 chromosome, complete genomeRluA family pseudouridine synthase5e-53207
NC_011725:3897450:391551739155173916425909Bacillus cereus B4264 chromosome, complete genomeribosomal large subunit pseudouridine synthase, RluA family7e-53207
NC_014171:3779956:379633737963373797245909Bacillus thuringiensis BMB171 chromosome, complete genomeribosomal large subunit pseudouridine synthase D8e-53207
NC_004722:3855326:387346538734653874373909Bacillus cereus ATCC 14579, complete genomeRibosomal large subunit pseudouridine synthase D8e-53207
NC_011772:3863166:388159338815933882501909Bacillus cereus G9842, complete genomeribosomal large subunit pseudouridine synthase, RluA family9e-53207
NC_005945:3693471:371199937119993712907909Bacillus anthracis str. Sterne, complete genomeRNA pseudouridylate synthase1e-52206
NC_003909:3671468:368929036892903690198909Bacillus cereus ATCC 10987, complete genomeribosomal large subunit pseudouridine synthase, RluD subfamily1e-52206
NC_012472:3743473:375933137593313760239909Bacillus cereus 03BB102, complete genomeribosomal large subunit pseudouridine synthase, RluA family1e-52206
NC_008600:3724312:374201937420193742927909Bacillus thuringiensis str. Al Hakam, complete genomeribosomal large subunit pseudouridine synthase D1e-52206
NC_014335:3645500:366205736620573662965909Bacillus cereus biovar anthracis str. CI chromosome, completeribosomal large subunit pseudouridylate synthase D1e-52206
NC_011773:3729500:374609037460903746998909Bacillus cereus AH820 chromosome, complete genomeribosomal large subunit pseudouridine synthase, RluA family1e-52206
NC_016779:3660000:367716336771633678071909Bacillus cereus F837/76 chromosome, complete genomeRibosomal large subunit pseudouridine synthase D1e-52206
NC_017200:3737185:375617137561713757079909Bacillus thuringiensis serovar finitimus YBT-020 chromosome,23S rRNA pseudouridine synthase D1e-52206
NC_007530:3694940:371143137114313712339909Bacillus anthracis str. 'Ames Ancestor', complete genome1e-52206
NC_016771:3633327:365237636523763653284909Bacillus cereus NC7401, complete genomeribosomal large subunit pseudouridine synthase D1e-52207
NC_011969:3627980:364383736438373644745909Bacillus cereus Q1 chromosome, complete genomeribosomal large subunit pseudouridine synthase, rlud subfamily1e-52207
NC_011658:3680829:369987836998783700786909Bacillus cereus AH187 chromosome, complete genomeRluA family ribosomal large subunit pseudouridine synthase1e-52207
NC_017208:3897253:391311939131193914027909Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeribosomal large subunit pseudouridine synthase D1e-52207
NC_012659:3692803:371133137113313712239909Bacillus anthracis str. A0248, complete genomeribosomal large subunit pseudouridine synthase, RluA family1e-52206
NC_003997:3692776:371130437113043712212909Bacillus anthracis str. Ames, complete genome1e-52206
NC_005957:3716487:373349837334983734406909Bacillus thuringiensis serovar konkukian str. 97-27, completeribosomal large subunit pseudouridine synthase D2e-52206
NC_006274:3773335:379174037917403792648909Bacillus cereus E33L, complete genomepseudouridylate synthase (pseudouridine synthase)2e-52206
NC_009674:2624817:264239926423992643307909Bacillus cytotoxicus NVH 391-98 chromosome, complete genomeRluA family pseudouridine synthase4e-52204
NC_010184:3757000:377138237713823772290909Bacillus weihenstephanensis KBAB4, complete genomepseudouridine synthase, RluA family4e-52205
NC_009718:1183816:120278612027861203730945Fervidobacterium nodosum Rt17-B1, complete genomeRluA family pseudouridine synthase2e-51202
NC_009848:1494253:149811214981121499026915Bacillus pumilus SAFR-032, complete genomepseudouridylate synthase2e-51202
NC_010321:1361748:138475413847541385671918Thermoanaerobacter pseudethanolicus ATCC 33223 chromosome, completeRluA family pseudouridine synthase3e-51202
NC_013921:1344000:136674913667491367666918Thermoanaerobacter italicus Ab9 chromosome, complete genomepseudouridine synthase, RluA family1e-50199
NC_002570:2649759:266682626668262667743918Bacillus halodurans C-125, complete genomehypothetical protein5e-50198
NC_015958:1465631:148911914891191490036918Thermoanaerobacter wiegelii Rt8.B1 chromosome, complete genomeRluA family pseudouridine synthase5e-50198
NC_014209:1363151:138671313867131387630918Thermoanaerobacter mathranii subsp. mathranii str. A3 chromosome,pseudouridine synthase, RluA family5e-50197
NC_017095:1429298:1429298142929814303321035Fervidobacterium pennivorans DSM 9078 chromosome, complete genomeRluA family pseudouridine synthase7e-50197
NC_016584:4961688:4980519498051949815381020Desulfosporosinus orientis DSM 765 chromosome, complete genomeRluA family pseudouridine synthase8e-50197
NC_002973:1877905:189889918988991899810912Listeria monocytogenes str. 4b F2365, complete genomeribosomal large subunit pseudouridine synthase, RluD subfamily1e-49196
NC_021171:1354000:135505513550551355966912Bacillus sp. 1NLA3E, complete genomepseudouridylate synthase1e-49196
NC_003212:1958500:197392719739271974835909Listeria innocua Clip11262, complete genomehypothetical protein2e-49196
NC_008555:1874878:189348218934821894390909Listeria welshimeri serovar 6b str. SLCC5334, complete genomeRibosomal large subunit pseudouridine synthase3e-49195
NC_013768:1983711:200471120047112005622912Listeria monocytogenes 08-5923, complete genomehypothetical protein3e-49195
NC_003210:1904152:191952519195251920436912Listeria monocytogenes EGD-e, complete genomehypothetical protein3e-49195
NC_012581:519969:526537526537527256720Bacillus anthracis str. CDC 684 chromosome, complete genomeribosomal large subunit pseudouridine synthase, RluA family4e-49195
NC_013891:1861294:187775718777571878668912Listeria seeligeri serovar 1/2b str. SLCC3954, complete genomeribosomal large subunit pseudouridine synthase, RluD subfamily8e-49194
NC_009614:769851:7765477765477776231077Bacteroides vulgatus ATCC 8482 chromosome, complete genomeribosomal large subunit pseudouridine synthase D2e-48193
NC_015391:1248583:125300512530051253910906Carnobacterium sp. 17-4 chromosome, complete genomepseudouridylate synthase5e-48191
NC_013517:300411:322992322992323843852Sebaldella termitidis ATCC 33386, complete genomepseudouridine synthase, RluA family6e-48191
NC_016584:3617439:363894836389483639841894Desulfosporosinus orientis DSM 765 chromosome, complete genomeRluA family pseudouridine synthase7e-48191
NC_011959:972798:997619997619998587969Thermomicrobium roseum DSM 5159, complete genomepseudouridine synthase, RluA family8e-48191
NC_017262:623351:624595624595625548954Zymomonas mobilis subsp. mobilis ATCC 10988 chromosome, completeRluA family pseudouridine synthase1e-47190
NC_015516:1222632:124152312415231242431909Melissococcus plutonius ATCC 35311, complete genomeribosomal large subunit pseudouridine synthase D2e-47189
NC_019978:875941:888249888249889166918Halobacteroides halobius DSM 5150, complete genomepseudouridine synthase, RluA family2e-47189
NC_011999:813978:826241826241827146906Macrococcus caseolyticus JCSC5402, complete genomehypothetical protein2e-47189
CP002516:1196000:119891411989141199894981Escherichia coli KO11, complete genomepseudouridine synthase, RluA family7e-47187
CP002185:2889656:290596329059632906943981Escherichia coli W, complete genome23S rRNA pseudouridine synthase7e-47187
CU928160:2785792:280209728020972803077981Escherichia coli IAI1 chromosome, complete genome23S rRNA pseudouridine synthase7e-47187
NC_007907:3230513:326353232635323264434903Desulfitobacterium hafniense Y51, complete genomehypothetical protein1e-46186
NC_013850:1198134:120102512010251202005981Klebsiella variicola At-22 chromosome, complete genomepseudouridine synthase, RluA family3e-46185
NC_007512:865500:8975048975048985681065Pelodictyon luteolum DSM 273, complete genomePseudouridine synthase, RluD3e-46185
NC_008740:979830:998331998331999308978Marinobacter aquaeolei VT8, complete genomepseudouridine synthase, RluA family4e-46185
NC_009648:3192483:320831432083143209294981Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genome23S rRNA pseudouridine synthase D4e-46185
NC_007350:1629694:164482916448291645746918Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305,putative pseudouridylate synthase6e-46184
NC_019903:2806466:282159028215902822588999Desulfitobacterium dichloroeliminans LMG P-21439 chromosome,ribosomal large subunit pseudouridine synthase D9e-46184
NC_010995:3821327:382290638229063823868963Cellvibrio japonicus Ueda107, complete genomepseudouridine synthase, RluA family subfamily1e-45183
NC_018080:5192264:519226451922645193226963Pseudomonas aeruginosa DK2 chromosome, complete genomepseudouridine synthase1e-45183
NC_014019:4094750:410837941083794109293915Bacillus megaterium QM B1551 chromosome, complete genomepseudouridine synthase4e-45181
NC_003366:2106937:212096721209672121887921Clostridium perfringens str. 13, complete genomehypothetical protein6e-45181
NC_017138:980696:984464984464985378915Bacillus megaterium WSH-002 chromosome, complete genomeRNA pseudouridine synthase ylyB7e-45181
NC_017517:749031:7670517670517681751125Neisseria meningitidis M01-240355 chromosome, complete genomeribosomal large subunit pseudouridine synthase D8e-45181
NC_011027:760221:7744797744797755281050Chlorobaculum parvum NCIB 8327, complete genomepseudouridine synthase, RluA family1e-44180
NC_017514:1520245:1521345152134515224691125Neisseria meningitidis M01-240149 chromosome, complete genomeribosomal large subunit pseudouridine synthase D2e-44179
NC_017518:795113:8123148123148134381125Neisseria meningitidis NZ-05/33 chromosome, complete genomeribosomal large subunit pseudouridine synthase D2e-44179
NC_007645:6049340:605012060501206051079960Hahella chejuensis KCTC 2396, complete genomePseudouridylate synthases, 23S RNA-specific2e-44179
NC_009439:1075170:109436910943691095343975Pseudomonas mendocina ymp, complete genomeribosomal large subunit pseudouridine synthase D2e-44179
NC_013016:633313:6471546471546482781125Neisseria meningitidis alpha14 chromosome, complete genomeribosomal large subunit pseudouridine synthase D3e-44179
NC_014833:2225233:224669122466912247605915Ruminococcus albus 7 chromosome, complete genomeRluA family pseudouridine synthase3e-44179
NC_003116:867943:8845868845868857101125Neisseria meningitidis Z2491, complete genomeribosomal large subunit pseudouridine synthase D4e-44178
NC_005773:866157:866157866157867119963Pseudomonas syringae pv. phaseolicola 1448A, complete genomeRibosomal large subunit pseudouridine synthase D(Pseudouridine synthase) (Uracil hydrolyase)4e-44178
NC_017512:642229:6553816553816565591179Neisseria meningitidis WUE 2594, complete genomeribosomal large subunit pseudouridine synthase D4e-44178
NC_017515:1555500:1556639155663915577631125Neisseria meningitidis M04-240196 chromosome, complete genomeribosomal large subunit pseudouridine synthase D4e-44178
NC_007775:723925:745386745386746318933Synechococcus sp. JA-3-3Ab, complete genomepseudouridine synthase, RluA family5e-44178
NC_007005:830467:830467830467831429963Pseudomonas syringae pv. syringae B728a, complete genomePseudouridine synthase, RluD5e-44178
NC_015410:1144272:116219211621921163175984Pseudomonas mendocina NK-01 chromosome, complete genomeribosomal large subunit pseudouridine synthase D5e-44178
NC_011653:1226035:125539712553971256134738Thermosipho africanus TCF52B, complete genomeribosomal large subunit pseudouridine synthase D8e-44177
NC_006905:2805877:282278428227842823764981Salmonella enterica subsp. enterica serovar Choleraesuis strpseudouridine synthase (pseudouridines 1911, 1915, 1917 in 23S RNA)9e-44177
NC_011149:2701916:271898227189822719962981Salmonella enterica subsp. enterica serovar Agona str. SL483,ribosomal large subunit pseudouridine synthase D9e-44177
NC_003198:2703013:272142727214272722407981Salmonella enterica subsp. enterica serovar Typhi str. CT18,ftsH suppressor protein SfhB9e-44177
NC_011080:2789744:280807228080722809052981Salmonella enterica subsp. enterica serovar Newport str. SL254,ribosomal large subunit pseudouridine synthase D9e-44177
NC_008260:497855:517349517349518320972Alcanivorax borkumensis SK2, complete genomepseudouridylate synthase1e-43176
NC_010120:662969:6770656770656782431179Neisseria meningitidis 053442, complete genomeribosomal large subunit pseudouridine synthase D1e-43176
NC_017505:721395:7385977385977397211125Neisseria meningitidis alpha710 chromosome, complete genomeputative ribosomal large subunit pseudouridine synthase D1e-43177
NC_011184:597496:600470600470601444975Vibrio fischeri MJ11 chromosome I, complete sequenceribosomal large subunit pseudouridine synthase D1e-43177
NC_017501:1633436:1637405163740516385291125Neisseria meningitidis 8013, complete genomeribosomal large subunit pseudouridine synthase D (rRNA-uridine isomerase D; rRNA pseudouridylate synthase D)1e-43177
NC_009485:7021228:704256170425617043541981Bradyrhizobium sp. BTAi1 chromosome, complete genomeribosomal large subunit pseudouridine synthase D1e-43177
NC_004578:895019:894060894060895022963Pseudomonas syringae pv. tomato str. DC3000, complete genome1e-43177
NC_003112:719490:7356717356717367951125Neisseria meningitidis MC58, complete genomeribosomal large subunit pseudouridine synthase D2e-43176
NC_011060:1898224:1902881190288119039301050Pelodictyon phaeoclathratiforme BU-1, complete genomepseudouridine synthase, RluA family2e-43176
NC_015556:4118304:411830441183044119278975Pseudomonas fulva 12-X chromosome, complete genomepseudouridine synthase, RluA family5e-43174
NC_009445:1453132:1457253145725314584071155Bradyrhizobium sp. ORS 278 chromosome, complete genomepseudouridine synthase2e-42173
NC_009337:1200722:1200722120072212017711050Chlorobium phaeovibrioides DSM 265 chromosome, complete genomeribosomal large subunit pseudouridine synthase D2e-42172
NC_016002:1975000:2022391202239120234791089Pseudogulbenkiania sp. NH8B, complete genomeribosomal large subunit pseudouridine synthase D2e-42172
NC_007618:1593886:1616512161651216175161005Brucella melitensis biovar Abortus 2308 chromosome I, completePrenyl group binding site (CAAX box):RNA-binding S4:Pseudouridine synthase:Pseudouridine synthase, Rlu:Pseudouridine synthase...3e-41169
NC_010742:1595065:1617689161768916186931005Brucella abortus S19 chromosome 1, complete sequenceribosomal large subunit pseudouridine synthase, RluD subfamily3e-41169
NC_010103:1577750:1600373160037316014161044Brucella canis ATCC 23365 chromosome I, complete sequencepseudouridine synthase, RluA family4e-41168
NC_007298:1721425:172142517214251722381957Dechloromonas aromatica RCB, complete genomePseudouridine synthase, RluD5e-41168
NC_014758:310394:318140318140319102963Calditerrivibrio nitroreducens DSM 19672 chromosome, completepseudouridine synthase, rlua family7e-41167
NC_007484:2893878:290025929002592901218960Nitrosococcus oceani ATCC 19707, complete genomePseudouridine synthase, RluD8e-41167
NC_016605:766836:787508787508788323816Pediococcus claussenii ATCC BAA-344 chromosome, complete genomeRluA family pseudouridine synthase1e-40167
NC_013894:117644:121943121943122917975Thermocrinis albus DSM 14484 chromosome, complete genomepseudouridine synthase, RluA family5e-40164
NC_014109:27500:406304063041478849Candidatus Riesia pediculicola USDA chromosome, complete genomeribosomal large subunit pseudouridine synthase D2e-39162
NC_015672:203139:208600208600209523924Flexistipes sinusarabici DSM 4947 chromosome, complete genomeRluA family pseudouridine synthase2e-39162
NC_010505:5967324:5971609597160959726131005Methylobacterium radiotolerans JCM 2831, complete genomepseudouridine synthase, RluA family2e-39163
NC_010172:1079127:1083687108368710847181032Methylobacterium extorquens PA1, complete genomepseudouridine synthase, RluA family2e-38159
NC_008702:1094663:109466310946631095637975Azoarcus sp. BH72, complete genomepseudouridylate synthase2e-38159
NC_014909:219498:2194982194982204991002Candidatus Blochmannia vafer str. BVAF chromosome, complete genomeribosomal large subunit pseudouridine synthase D2e-38159
NC_008781:1973826:1988744198874419897781035Polaromonas naphthalenivorans CJ2, complete genomepseudouridine synthase, RluA family5e-38158
NC_013166:1149760:114878911487891149763975Kangiella koreensis DSM 16069, complete genomepseudouridine synthase, RluA family1e-37157
NC_012808:806432:809836809836810828993Methylobacterium extorquens AM1, complete genomeribosomal large subunit pseudouridine synthase D (Pseudouridylate synthase) (Uracil hydrolyase)1e-37156
NC_002162:333303:356922356922357821900Ureaplasma parvum serovar 3 str. ATCC 700970, complete genomepseudouridine synthase (uracil hydrolase)2e-37156
NC_010503:327517:356961356961357839879Ureaplasma parvum serovar 3 str. ATCC 27815 chromosome, completepseudouridylate synthase, 23S RNA-specific2e-37155
NC_014623:4535544:456108945610894561898810Stigmatella aurantiaca DW4/3-1 chromosome, complete genomepseudouridine synthase8e-37154
NC_011365:502620:518134518134519102969Gluconacetobacter diazotrophicus PAl 5 chromosome, complete genomeRluA family pseudouridine synthase2e-36152
NC_015557:1412917:141710014171001418026927Hydrogenobaculum sp. 3684 chromosome, complete genomepseudouridine synthase, RluA family3e-36152
NC_015587:1414304:141696814169681417894927Hydrogenobaculum sp. SHO chromosome, complete genomepseudouridine synthase, RluA family3e-36152
NC_014313:2059933:2064023206402320650571035Hyphomicrobium denitrificans ATCC 51888 chromosome, completepseudouridine synthase, RluA family3e-36152
NC_011126:1430608:143480014348001435726927Hydrogenobaculum sp. Y04AAS1, complete genomepseudouridine synthase, RluA family4e-36151
NC_017277:2039097:204081620408162041799984Synechocystis sp. PCC 6803, complete genomehypothetical protein5e-36151
NC_010125:2295500:230997723099772310864888Gluconacetobacter diazotrophicus PAl 5, complete genomeputative ribosomal large subunit pseudouridine synthase D7e-36150
NC_003450:2244862:226000022600002260932933Corynebacterium glutamicum ATCC 13032, complete genome23S RNA-specific pseudouridylate synthase8e-36150
NC_006958:2214893:223003222300322230964933Corynebacterium glutamicum ATCC 13032, complete genomeRIBOSOMAL LARGE SUBUNIT PSEUDOURIDINE SYNTHASE D8e-36150
NC_009342:2211000:222400222240022224934933Corynebacterium glutamicum R chromosome, complete genomehypothetical protein8e-36150
NC_013520:1860286:187477318747731875639867Veillonella parvula DSM 2008, complete genomepseudouridine synthase, RluA family1e-35150
NC_014935:836868:856068856068857051984Nitratifractor saLSUginis DSM 16511 chromosome, complete genomeribosomal large subunit pseudouridine synthase d1e-35150
NC_010730:180000:192216192216193172957Sulfurihydrogenibium sp. YO3AOP1, complete genomepseudouridine synthase, RluA family2e-35149
NC_015697:1814128:184096018409601841865906Lactobacillus reuteri SD2112 chromosome, complete genomeribosomal large subunit pseudouridine synthase5e-34144
NC_009513:618000:638140638140639045906Lactobacillus reuteri F275, complete genomepseudouridine synthase, RluA family1e-33144
NC_011978:1581994:160696516069651607879915Thermotoga neapolitana DSM 4359, complete genomePseudouridine synthase4e-33142
NC_013123:59918:618716187162611741Candidatus Sulcia muelleri SMDSEM, complete genomeputative RNA pseudouridine synthase fragment2e-32139
NC_014168:1411310:142496314249631425910948Segniliparus rotundus DSM 44985 chromosome, complete genomepseudouridine synthase, RluA family2e-32140
NC_018507:339000:341539341539342468930Candidatus Portiera aleyrodidarum BT-B chromosome, complete genome23S RNA-specific pseudouridylate synthase3e-32139
NC_018677:329829:334956334956335885930Candidatus Portiera aleyrodidarum BT-B-HRs chromosome, completeRibosomal large subunit pseudouridine synthase D3e-32139
NC_014219:1736000:175471317547131755630918Bacillus selenitireducens MLS10 chromosome, complete genomepseudouridine synthase6e-32138
NC_014100:533322:5553445553445563661023Caulobacter segnis ATCC 21756 chromosome, complete genomepseudouridine synthase7e-32137
NC_014622:4361553:437035743703574371268912Paenibacillus polymyxa SC2 chromosome, complete genomepseudouridine synthase6e-31134
NC_012225:2198987:221853322185332219522990Brachyspira hyodysenteriae WA1, complete genomePseudouridylate synthase2e-30133
NC_015711:4811349:481618448161844817134951Myxococcus fulvus HW-1 chromosome, complete genomeRluA family pseudouridine synthase3e-30132
NC_015732:3017387:302073630207363021443708Spirochaeta caldaria DSM 7334 chromosome, complete genomepseudouridine synthase3e-30132
NC_016629:3543432:3558324355832435599941671Desulfovibrio africanus str. Walvis Bay chromosome, completedephospho-CoA kinase5e-30131
NC_009785:2049395:207462320746232075495873Streptococcus gordonii str. Challis substr. CH1, complete genomeribosomal large subunit pseudouridine synthase D1e-28127
NC_013520:1860286:1861671186167118627891119Veillonella parvula DSM 2008, complete genomepseudouridine synthase3e-28125
NC_016513:54802:551875518756146960Aggregatibacter actinomycetemcomitans ANH9381 chromosome, complete23S rRNA pseudouridylate synthase C3e-28125
NC_005773:1851116:186508118650811865794714Pseudomonas syringae pv. phaseolicola 1448A, complete genomeribosomal large subunit pseudouridine synthase A4e-28125
NC_013722:1905655:190565519056551906647993Xanthomonas albilineans, complete genomeprobable pseudouridine synthase (rna-uridine isomerase) (rna pseudouridylate synthase) protein7e-28124
NC_017271:2449504:247192524719252472869945Xanthomonas campestris pv. raphani 756C chromosome, completeribosomal large subunit pseudouridine synthase C7e-28124
NC_011653:1226035:122987212298721230753882Thermosipho africanus TCF52B, complete genomeribosomal large subunit pseudouridine synthase C1e-27124
NC_003228:2973266:299588229958822996799918Bacteroides fragilis NCTC 9343, complete genomeputative RNA pseudouridylate synthase2e-27123
NC_015556:1899850:191389519138951914530636Pseudomonas fulva 12-X chromosome, complete genomepseudouridine synthase5e-27121
NC_017503:770451:784883784883785818936Mycoplasma gallisepticum str. F chromosome, complete genomePseudouridine synthase8e-27120
NC_014394:1325616:134437013443701345329960Gallionella capsiferriformans ES-2 chromosome, complete genomepseudouridine synthase, RluA family1e-26120
NC_007760:308500:309958309958310896939Anaeromyxobacter dehalogenans 2CP-C, complete genomePseudouridine synthase, RluD3e-26119
NC_018691:3041851:304259830425983043554957Alcanivorax dieselolei B5 chromosome, complete genomePseudouridine synthase4e-26119
NC_007798:112840:118090118090119082993Neorickettsia sennetsu str. Miyayama, complete genomeribosomal large subunit pseudouridine synthases, RluA family4e-26119
NC_013132:5462652:5483579548357954852911713Chitinophaga pinensis DSM 2588, complete genomepseudouridine synthase5e-26118
NC_008463:1912348:191380619138061914441636Pseudomonas aeruginosa UCBPP-PA14, complete genomeribosomal large subunit pseudouridine synthase A7e-26117
NC_011145:306623:312459312459313397939Anaeromyxobacter sp. K, complete genomepseudouridine synthase, RluA family1e-25117
NC_019960:801589:809635809635810534900Prevotella dentalis DSM 3688 chromosome 1, complete sequencepseudouridine synthase, RluA family2e-25116
NC_014727:1512546:151880015188001519648849Lactobacillus delbrueckii subsp. bulgaricus ND02 chromosome,pseudouridylate synthase, 23S RNA-specific5e-25115
NC_012912:1788308:184304218430421844004963Dickeya zeae Ech1591, complete genomepseudouridine synthase, RluA family6e-25115
NC_016002:3077648:307764830776483078589942Pseudogulbenkiania sp. NH8B, complete genomeribosomal large subunit pseudouridine synthase C7e-25114
NC_020211:2012480:204614220461422047101960Serratia marcescens WW4, complete genome23S rRNA pseudouridine synthase7e-25114
NC_008702:2039462:204514720451472045857711Azoarcus sp. BH72, complete genomepseudouridine synthase A3e-24112
NC_016048:1930089:195945119594511960410960Oscillibacter valericigenes Sjm18-20, complete genomeputative pseudouridine synthase4e-24112
NC_009465:29735:805698056981480912Candidatus Vesicomyosocius okutanii HA, complete genomeribosomal large subunit pseudouridine synthase C8e-24110
NC_009667:1076718:109454710945471095215669Ochrobactrum anthropi ATCC 49188 chromosome 1, complete sequencepseudouridine synthase1e-23110
NC_018645:247917:263207263207263935729Desulfobacula toluolica Tol2, complete genomeRNA pseudouridine synthase2e-23109
NC_015696:517941:550841550841551764924Francisella sp. TX077308 chromosome, complete genomeribosomal large subunit pseudouridine synthase C4e-23108
NC_013009:122000:129077129077130024948Neorickettsia risticii str. Illinois, complete genomeribosomal large subunit pseudouridine synthase, RluA family5e-23108
NC_012214:1212616:123037912303791231077699Erwinia pyrifoliae Ep1/96, complete genomePseudouridine synthase7e-23108
NC_010336:996661:102939210293921030321930Francisella philomiragia subsp. philomiragia ATCC 25017, completeLysozyme7e-23107
NC_015276:2171355:218401821840182184992975Marinomonas mediterranea MMB-1 chromosome, complete genomepseudouridine synthase, RluA family1e-22107
NC_010001:3369500:3394840339484033958801041Clostridium phytofermentans ISDg, complete genomepseudouridine synthase, RluA family2e-22106
NC_010634:732016:738044738044738664621Yersinia pseudotuberculosis PB1/+, complete genomepseudouridine synthase6e-22104
NC_008149:442168:448988448988449608621Yersinia pestis Nepal516, complete genomeribosomal large subunit pseudouridine synthase A6e-22104
NC_010465:3919572:393162039316203932240621Yersinia pseudotuberculosis YPIII, complete genomepseudouridine synthase6e-22104
NC_004088:4073698:408819840881984088818621Yersinia pestis KIM, complete genomehypothetical protein6e-22104
NC_010159:770172:782213782213782833621Yersinia pestis Angola, complete genomeribosomal large subunit pseudouridine synthase A6e-22104
NC_005810:4183297:419534541953454195965621Yersinia pestis biovar Microtus str. 91001, complete genomeribosomal large subunit pseudouridine synthase A6e-22104
NC_008150:4601202:460802246080224608642621Yersinia pestis Antiqua, complete genomeribosomal large subunit pseudouridine synthase A6e-22104
NC_003143:524755:529785529785530405621Yersinia pestis CO92, complete genomeribosomal large subunit pseudouridine synthase A6e-22104
NC_006155:751235:756284756284756904621Yersinia pseudotuberculosis IP 32953, complete genome23S rRNA pseudouridylate 746 synthase6e-22104
NC_017265:3861259:386726838672683867888621Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,Ribosomal large subunit pseudouridine synthase A6e-22104
NC_017168:561402:573450573450574070621Yersinia pestis A1122 chromosome, complete genomeribosomal large subunit pseudouridine synthase A6e-22104
NC_017160:520799:527619527619528239621Yersinia pestis D182038 chromosome, complete genomeribosomal large subunit pseudouridine synthase A6e-22104
NC_017154:520400:525430525430526050621Yersinia pestis D106004 chromosome, complete genomeribosomal large subunit pseudouridine synthase A6e-22104
NC_014029:576459:583279583279583899621Yersinia pestis Z176003 chromosome, complete genomeribosomal large subunit pseudouridine synthase A6e-22104
NC_009708:3862044:387654438765443877164621Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeribosomal large subunit pseudouridine synthase A6e-22104
NC_009381:3558018:357006635700663570686621Yersinia pestis Pestoides F chromosome, complete genomeribosomal large subunit pseudouridine synthase A6e-22104
NC_012026:415447:426791426791427681891Anaplasma marginale str. Florida, complete genomeribosomal large subunit pseudouridine synthase (rluC)8e-22104
NC_013203:472679:473622473622474362741Atopobium parvulum DSM 20469, complete genomepseudouridine synthase9e-22104
NC_012913:1832500:183708618370861837745660Aggregatibacter aphrophilus NJ8700, complete genomeribosomal large subunit pseudouridine synthase A1e-21103
NC_007759:2179000:221521822152182216192975Syntrophus aciditrophicus SB, complete genomeribosomal large subunit pseudouridine synthase D1e-21103
NC_020064:1409596:142726314272631427961699Serratia marcescens FGI94, complete genome23S RNA-specific pseudouridylate synthase1e-21103
NC_012489:4336790:4336790433679043382201431Gemmatimonas aurantiaca T-27, complete genomeribosomal large subunit pseudouridine synthase A1e-21103
NC_013172:2556517:255907925590792560035957Brachybacterium faecium DSM 4810, complete genomepseudouridine synthase, RluA family3e-21102
NC_012483:996555:101778110177811018686906Acidobacterium capsulatum ATCC 51196, complete genomepseudouridine synthase, RluA family6e-21101
NC_009089:4177117:418183241818324182497666Clostridium difficile 630, complete genomeputative pseudouridylate synthase1e-20100
NC_013315:3978495:397936739793673980032666Clostridium difficile CD196 chromosome, complete genomepseudouridylate synthase1e-20100
NC_017179:3984000:398738739873873988052666Clostridium difficile BI1, complete genomepseudouridylate synthase1e-20100
NC_014838:175939:176495176495177193699Pantoea sp. At-9b plasmid pPAT9B01, complete sequencepseudouridine synthase1e-20100
NC_012808:157156:1793321793321807231392Methylobacterium extorquens AM1, complete genomePseudouridine synthase, RluD2e-2099.8
NC_009749:1699152:173248617324861733415930Francisella tularensis subsp. holarctica FTA, complete genomepseudouridine synthase, RluA family3e-2099
NC_008601:1733940:176808817680881769017930Francisella tularensis subsp. novicida U112, complete genomeribosomal large subunit pseudouridine synthase C3e-2099
NC_008245:24652:573315733158260930Francisella tularensis subsp. tularensis FSC 198, complete genomeribosomal large subunit pseudouridine synthase C3e-2099
NC_006570:24636:573155731558244930Francisella tularensis subsp. tularensis Schu 4, complete genomeribosomal large subunit pseudouridine synthase C3e-2099
NC_016933:24654:573335733358262930Francisella tularensis TIGB03 chromosome, complete genomeribosomal large subunit pseudouridine synthase C3e-2099
NC_016937:24654:573335733358262930Francisella tularensis subsp. tularensis TI0902 chromosome,ribosomal large subunit pseudouridine synthase C3e-2099
NC_010725:356609:3759603759603773001341Methylobacterium populi BJ001, complete genomepseudouridine synthase, RluA family3e-2099
NC_008369:1702885:173621917362191737148930Francisella tularensis subsp. holarctica OSU18, complete genomepseudouridylate synthase3e-2099.4
NC_007880:1703346:173658917365891737518930Francisella tularensis subsp. holarctica, complete genomeribosomal large subunit pseudouridine synthase C3e-2099.4
NC_012912:647369:648463648463649116654Dickeya zeae Ech1591, complete genomepseudouridine synthase3e-2099.4
NC_009257:109528:142216142216143145930Francisella tularensis subsp. tularensis WY96-3418 chromosome,ribosomal large subunit pseudouridine synthase C3e-2099.4
NC_009524:1488714:149353914935391494309771Psychrobacter sp. PRwf-1 chromosome, complete genomepseudouridine synthase3e-2099.4
NC_015224:1914833:192806319280631928761699Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,putative ribosomal large subunit pseudouridine synthase3e-2099.4
NC_010677:96470:129164129164130093930Francisella tularensis subsp. mediasiatica FSC147, complete genomeribosomal large subunit pseudouridine synthase C4e-2098.6
NC_009648:2465613:249404424940442494835792Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genomeputative ribosomal large subunit pseudouridine synthase A5e-2098.6
NC_009138:2242470:225216222521622252833672Herminiimonas arsenicoxydans, complete genome23S rRNA pseudouridylate 746 synthase5e-2098.6
NC_014932:985882:100577010057701006753984Bartonella clarridgeiae 73, complete genomeribosomal large subunit pseudouridine synthase C5e-2098.6
NC_016845:3238507:326525132652513266042792Klebsiella pneumoniae subsp. pneumoniae HS11286 chromosome,putative ribosomal large subunit pseudouridine synthase A8e-2097.8
NC_010524:3391075:339400033940003394770771Leptothrix cholodnii SP-6, complete genomepseudouridine synthase8e-2097.8
NC_011891:315182:321023321023321961939Anaeromyxobacter dehalogenans 2CP-1, complete genomepseudouridine synthase, RluA family9e-2097.4
NC_008609:1976403:198319419831941983910717Pelobacter propionicus DSM 2379, complete genomepseudouridine synthase1e-1997.1
NC_014623:4662990:467010346701034670999897Stigmatella aurantiaca DW4/3-1 chromosome, complete genomepseudouridine synthase4e-1995.5
NC_012731:3193880:321645132164513217149699Klebsiella pneumoniae NTUH-K2044 chromosome, complete genomeputative ribosomal large subunit pseudouridine synthase A5e-1995.1
NC_011146:4070000:407167040716704072563894Geobacter bemidjiensis Bem, complete genomepseudouridine synthase, RluA family8e-1994.7
NC_007645:2181739:218907821890782190025948Hahella chejuensis KCTC 2396, complete genomePseudouridylate synthases, 23S RNA-specific8e-1994.7
NC_017030:7514500:753649575364957537421927Corallococcus coralloides DSM 2259 chromosome, complete genomeRluA family pseudouridine synthase1e-1894
NC_014721:1629063:164993016499301650865936Caldicellulosiruptor kristjanssonii 177R1B chromosome, completepseudouridine synthase1e-1894.4
NC_009850:11076:243402434025242903Arcobacter butzleri RM4018, complete genomeribosomal large subunit pseudouridine synthase4e-1892.4
NC_017187:10320:237642376424666903Arcobacter butzleri ED-1, complete genomeribosomal large subunit pseudouridine synthase4e-1892
NC_013730:4118355:412193641219364122670735Spirosoma linguale DSM 74, complete genomepseudouridine synthase5e-1891.7
NC_008343:88184:108404108404109078675Granulibacter bethesdensis CGDNIH1, complete genomeribosomal large subunit pseudouridine synthase A6e-1891.7
NC_009615:1734752:174680217468021747476675Parabacteroides distasonis ATCC 8503 chromosome, complete genomeribosomal large subunit pseudouridine synthase D8e-1891.3
NC_014012:1421979:143208114320811432959879Shewanella violacea DSS12, complete genometRNA pseudouridine synthase C2e-1790.1
NC_012968:865465:8860638860638870851023Methylotenera mobilis JLW8, complete genomepseudouridine synthase, RluA family2e-1789.7
NC_017043:1055569:106621410662141067125912Rickettsia montanensis str. OSU 85-930 chromosome, complete genomeribosomal large subunit pseudouridine synthase C3e-1789.4
NC_007513:728324:751333751333751977645Synechococcus sp. CC9902, complete genomeputative pseudouridylate synthase3e-1789
NC_016915:346000:349673349673350584912Rickettsia rickettsii str. Hlp#2 chromosome, complete genomeribosomal large subunit pseudouridine synthase C1e-1687.4
NC_015714:238891:238891238891239541651Treponema paraluiscuniculi Cuniculi A chromosome, complete genomepseudouridylate synthase4e-1685.5
NC_016513:1529691:153521415352141535909696Aggregatibacter actinomycetemcomitans ANH9381 chromosome, completepseudouridine synthase Rlu family protein8e-1684.7
NC_017066:312000:316035316035316946912Rickettsia typhi str. TH1527 chromosome, complete genomeribosomal large subunit pseudouridine synthase C1e-1584.3
NC_006142:312000:316021316021316932912Rickettsia typhi str. Wilmington, complete genomePseudouridine synthase.1e-1584.3
NC_016002:2946702:294670229467022947463762Pseudogulbenkiania sp. NH8B, complete genometRNA pseudouridine synthase C1e-1584.3
NC_011901:1122357:114356511435651144272708Thioalkalivibrio sulfidophilus HL-EbGr7 chromosome, completetRNA pseudouridine synthase C2e-1583.2
NC_002162:138334:144136144136145083948Ureaplasma parvum serovar 3 str. ATCC 700970, complete genomepseudouridine synthase (uracil hydrolase)3e-1582.4
NC_018643:673195:675234675234676145912Alpha proteobacterium HIMB5 chromosome, complete genomeRNA pseudouridylate synthase,S4 domain-containing protein9e-1581.3
NC_015276:1947936:194793619479361948622687Marinomonas mediterranea MMB-1 chromosome, complete genomepseudouridine synthase1e-1480.5
NC_017080:2340880:236236123623612363158798Phycisphaera mikurensis NBRC 102666, complete genomeputative pseudouridine synthase1e-1480.5
NC_007575:601256:619142619142619867726Sulfurimonas denitrificans DSM 1251, complete genomepseudouridine synthase1e-1480.9
NC_014166:2498500:250372525037252504474750Arcobacter nitrofigilis DSM 7299 chromosome, complete genomepseudouridine synthase2e-1480.1
NC_009655:1357486:136085113608511361567717Actinobacillus succinogenes 130Z chromosome, complete genometRNA pseudouridine synthase C2e-1479.7
NC_014218:1437931:145386314538631454792930Arcanobacterium haemolyticum DSM 20595 chromosome, complete genomepseudouridine synthase2e-1479.7
NC_012115:1415827:141892314189231419684762Nautilia profundicola AmH, complete genomeribosomal pseudouridine synthase2e-1376.6
NC_007645:2294553:229617922961792297072894Hahella chejuensis KCTC 2396, complete genomePseudouridylate synthases, 23S RNA-specific3e-1375.9
NC_015160:585220:604386604386605078693Odoribacter splanchnicus DSM 20712 chromosome, complete genomepseudouridine synthase4e-1375.9
NC_007963:3225306:322626032262603227045786Chromohalobacter salexigens DSM 3043, complete genomepseudouridine synthase6e-1375.1
NC_017294:327433:345339345339346328990Candidatus Arthromitus sp. SFB-mouse-Yit, complete genomeribosomal large subunit pseudouridine synthase C1e-1274.3
NC_010334:722408:733543733543734481939Shewanella halifaxensis HAW-EB4, complete genomepseudouridine synthase3e-1272.8
NC_011770:3626000:362949136294913630393903Pseudomonas aeruginosa LESB58, complete genomeputative pseudouridylate synthase6e-1271.6
NC_007508:5093365:509859350985935099483891Xanthomonas campestris pv. vesicatoria str. 85-10, complete genomeputative pseudouridylate synthase8e-1271.2
NC_015683:2469481:2479631247963124806381008Corynebacterium ulcerans BR-AD22 chromosome, complete genomehypothetical protein1e-1170.5
NC_005070:2181000:218285321828532183800948Synechococcus sp. WH 8102, complete genomeprobable pseudouridine synthase1e-1170.5
NC_002516:2222896:223543022354302236332903Pseudomonas aeruginosa PAO1, complete genomehypothetical protein2e-1170.1
NC_017271:4852351:485858348585834859404822Xanthomonas campestris pv. raphani 756C chromosome, completepseudouridylate synthase2e-1170.1
NC_008463:3394000:339786833978683398770903Pseudomonas aeruginosa UCBPP-PA14, complete genomeputative pseudouridylate synthase3e-1169.7
NC_003902:4989855:499584649958464996742897Xanthomonas campestris pv. campestris str. ATCC 33913, completepseudouridylate synthase7e-1168.2
NC_007086:5064053:507004450700445070940897Xanthomonas campestris pv. campestris str. 8004, complete genomepseudouridylate synthase7e-1168.2
NC_010688:4991410:500028350002835001242960Xanthomonas campestris pv. campestris, complete genomePutative pseudouridylate synthase9e-1167.8
NC_014844:2028666:204709220470922047961870Desulfovibrio aespoeensis Aspo-2 chromosome, complete genomepseudouridine synthase1e-1067
NC_010322:1817598:186779518677951868679885Pseudomonas putida GB-1 chromosome, complete genomepseudouridine synthase2e-1066.6
NC_014924:1762995:178173417817341782582849Pseudoxanthomonas suwonensis 11-1 chromosome, complete genomepseudouridine synthase4e-1065.5
NC_009901:3317068:333477933347793335696918Shewanella pealeana ATCC 700345, complete genomepseudouridine synthase2e-0963.5
NC_004369:2968251:2976199297619929772211023Corynebacterium efficiens YS-314, complete genomehypothetical protein6e-0961.6
NC_020409:297258:301476301476302306831Desulfovibrio piezophilus str. nov C1TLV30 chromosome, completePseudouridine synthase9e-0961.2
NC_017501:1493292:149910914991091500032924Neisseria meningitidis 8013, complete genomeputative RNA pseudouridine synthase (RNA-uridine isomerase; RNA pseudouridylate synthase)1e-0757
NC_014306:3006028:302803830280383028655618Erwinia billingiae Eb661, complete genomePseudouridine synthase2e-0757
NC_008767:804655:817471817471818394924Neisseria meningitidis FAM18, complete genomehypothetical protein3e-0756.2
NC_003116:1018813:103318110331811034104924Neisseria meningitidis Z2491, complete genomehypothetical protein5e-0755.5
NC_017512:789600:803965803965804888924Neisseria meningitidis WUE 2594, complete genomeputative RNA pseudouridine synthase (RNA-uridine isomerase; RNA pseudouridylate synthase)5e-0755.5
NC_017516:1408000:141190014119001412823924Neisseria meningitidis H44/76 chromosome, complete genomeRNA pseudouridine synthase5e-0755.5
NC_017517:898771:911589911589912512924Neisseria meningitidis M01-240355 chromosome, complete genomeRNA pseudouridine synthase5e-0755.5
NC_017515:1402218:140602614060261406949924Neisseria meningitidis M04-240196 chromosome, complete genomeRNA pseudouridine synthase6e-0755.1
NC_006361:792904:807653807653808582930Nocardia farcinica IFM 10152, complete genomeputative RNA pseudouridylate synthase8e-0754.7
NC_008752:2936933:293937629393762940299924Acidovorax avenae subsp. citrulli AAC00-1, complete genomepseudouridine synthase8e-0754.7
NC_014721:1629063:163588416358841636606723Caldicellulosiruptor kristjanssonii 177R1B chromosome, completepseudouridine synthase4e-0652.4
NC_007798:112840:112840112840113199360Neorickettsia sennetsu str. Miyayama, complete genomeputative RNA pseudouridylate synthase, truncation8e-0651.6