Pre_GI: BLASTP Hits

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Query: NC_017168:561402:571484 Yersinia pestis A1122 chromosome, complete genome

Start: 571484, End: 572227, Length: 744

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:3861259:386911138691113869854744Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein5e-144509
NC_004088:4073698:408623240862324086975744Yersinia pestis KIM, complete genomehypothetical protein5e-144509
NC_005810:4183297:419337941933794194122744Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein5e-144509
NC_008149:442168:450831450831451574744Yersinia pestis Nepal516, complete genomehypothetical protein5e-144509
NC_010159:770172:780246780246780989744Yersinia pestis Angola, complete genomehypothetical protein5e-144509
NC_003143:524755:531628531628532371744Yersinia pestis CO92, complete genomehypothetical protein5e-144509
NC_010634:732016:739887739887740630744Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein5e-144509
NC_010465:3919572:392965439296543930397744Yersinia pseudotuberculosis YPIII, complete genomehypothetical protein5e-144509
NC_006155:751235:758127758127758870744Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein5e-144509
NC_009708:3862044:387457838745783875321744Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein5e-144509
NC_014029:576459:585122585122585865744Yersinia pestis Z176003 chromosome, complete genomehypothetical protein5e-144509
NC_017160:520799:529462529462530205744Yersinia pestis D182038 chromosome, complete genomehypothetical protein5e-144509
NC_017154:520400:527273527273527935663Yersinia pestis D106004 chromosome, complete genomehypothetical protein2e-126451
NC_009381:3558018:356818135681813568843663Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein2e-126451
NC_008150:4601202:460986546098654610527663Yersinia pestis Antiqua, complete genomehypothetical protein2e-126451