Pre_GI: BLASTP Hits

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Query: NC_017168:561402:570141 Yersinia pestis A1122 chromosome, complete genome

Start: 570141, End: 571154, Length: 1014

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:3861259:3870184387018438711971014Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein0699
NC_017160:520799:5305355305355315481014Yersinia pestis D182038 chromosome, complete genomehypothetical protein0699
NC_017154:520400:5283465283465293591014Yersinia pestis D106004 chromosome, complete genomehypothetical protein0699
NC_014029:576459:5861955861955872081014Yersinia pestis Z176003 chromosome, complete genomehypothetical protein0699
NC_009708:3862044:3873235387323538742481014Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeImpA domain-containing protein0699
NC_004088:4073698:4084889408488940859021014Yersinia pestis KIM, complete genomehypothetical protein0699
NC_005810:4183297:4192036419203641930491014Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein0699
NC_003143:524755:5327015327015337141014Yersinia pestis CO92, complete genomehypothetical protein0699
NC_006155:751235:7592007592007602131014Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein0699
NC_010159:770172:7789037789037799161014Yersinia pestis Angola, complete genomeImpA domain protein0698
NC_009381:3558018:356675735667573567755999Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein0690
NC_008150:4601202:461095346109534611951999Yersinia pestis Antiqua, complete genomehypothetical protein0690
NC_008149:442168:451919451919452917999Yersinia pestis Nepal516, complete genomehypothetical protein0690
NC_010634:732016:740987740987741973987Yersinia pseudotuberculosis PB1/+, complete genomeImpA domain-containing protein0681
NC_010465:3919572:392831139283113929297987Yersinia pseudotuberculosis YPIII, complete genomeImpA domain protein0681
NC_020211:3398281:340947234094723410437966Serratia marcescens WW4, complete genomeImpA domain protein6e-72271
NC_020064:2921809:2926225292622529272561032Serratia marcescens FGI94, complete genometype VI secretion-associated protein, ImpA family1e-1377.4
NC_014306:679888:6842586842586852741017Erwinia billingiae Eb661, complete genomeconserved uncharacterized protein1e-1273.9
NC_016816:1823127:1827492182749218285141023Pantoea ananatis LMG 5342, complete genometype VI secretion-associated protein, ImpA family2e-1067