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Query: NC_017168:561402:566861 Yersinia pestis A1122 chromosome, complete genome

Start: 566861, End: 567304, Length: 444

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:3861259:387403438740343874477444Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein1e-80297
NC_010465:3919572:392503139250313925474444Yersinia pseudotuberculosis YPIII, complete genometype VI secretion system lysozyme-related protein1e-80297
NC_004088:4073698:408160940816094082052444Yersinia pestis KIM, complete genomehypothetical protein1e-80297
NC_006155:751235:763050763050763493444Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein1e-80297
NC_003143:524755:536551536551536994444Yersinia pestis CO92, complete genomehypothetical protein1e-80297
NC_005810:4183297:418875641887564189199444Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein1e-80297
NC_008149:442168:455754455754456197444Yersinia pestis Nepal516, complete genomehypothetical protein1e-80297
NC_010634:732016:744810744810745253444Yersinia pseudotuberculosis PB1/+, complete genometype VI secretion system lysozyme-related protein1e-80297
NC_010159:770172:775623775623776066444Yersinia pestis Angola, complete genomehypothetical protein1e-80297
NC_017160:520799:534385534385534828444Yersinia pestis D182038 chromosome, complete genomehypothetical protein1e-80297
NC_017154:520400:532196532196532639444Yersinia pestis D106004 chromosome, complete genomehypothetical protein1e-80297
NC_014029:576459:590045590045590488444Yersinia pestis Z176003 chromosome, complete genomehypothetical protein1e-80297
NC_009708:3862044:386995538699553870398444Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein1e-80297
NC_009381:3558018:356347735634773563920444Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein1e-80297
NC_020211:3398281:340608334060833406529447Serratia marcescens WW4, complete genomehypothetical protein8e-50195
NC_010625:670482:670482670482671033552Burkholderia phymatum STM815 plasmid pBPHY01, complete sequencetype VI secretion system lysozyme-related protein4e-0857
NC_012779:2619871:263566226356622636138477Edwardsiella ictaluri 93-146, complete genomehypothetical protein5e-0753.1
NC_012721:182965:182450182450182968519Burkholderia glumae BGR1 chromosome 2, complete genomehypothetical protein4e-0650.1