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Query: NC_017168:3977767:4011737 Yersinia pestis A1122 chromosome, complete genome

Start: 4011737, End: 4012057, Length: 321

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_005810:1467772:147592514759251476245321Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein2e-45181
NC_008149:2802392:283635628363562836676321Yersinia pestis Nepal516, complete genomehypothetical protein2e-45181
NC_003143:1630000:164701416470141647334321Yersinia pestis CO92, complete genomehypothetical protein2e-45181
NC_010634:1755548:176666017666601766980321Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein2e-45181
NC_008150:844727:858919858919859239321Yersinia pestis Antiqua, complete genomehypothetical protein2e-45181
NC_010465:2820500:286551628655162865836321Yersinia pseudotuberculosis YPIII, complete genomehypothetical protein2e-45181
NC_006155:1756000:176641217664121766732321Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein2e-45181
NC_010159:3120642:312929031292903129508219Yersinia pestis Angola, complete genomehypothetical protein5e-24109