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Query: NC_017168:3286:7876 Yersinia pestis A1122 chromosome, complete genome

Start: 7876, End: 9099, Length: 1224

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:809943:8118548118548130771224Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein0701
NC_017160:905783:9076949076949089171224Yersinia pestis D182038 chromosome, complete genomehypothetical protein0701
NC_009381:588137:5900485900485912711224Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein0701
NC_008150:317903:3207483207483219711224Yersinia pestis Antiqua, complete genomehypothetical protein0701
NC_005810:3917254:3921844392184439230671224Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein0701
NC_009708:874770:8766828766828779051224Yersinia pseudotuberculosis IP 31758 chromosome, complete genomemajor facilitator transporter0697
NC_010465:893921:8958338958338970561224Yersinia pseudotuberculosis YPIII, complete genomemajor facilitator superfamily MFS_10691
NC_014029:961522:9635449635449646561113Yersinia pestis Z176003 chromosome, complete genomehypothetical protein0645
NC_017154:902739:9056959056959067021008Yersinia pestis D106004 chromosome, complete genomehypothetical protein9e-132470
NC_011747:11532:1339213392145851194Escherichia coli S88 plasmid pECOS88, complete sequenceputative membrane transport protein ShiF1e-90333
NC_004431:3409389:3469278346927834704711194Escherichia coli CFT073, complete genomeshiF protein1e-85317
NC_004337:3590323:3819521381952138207141194Shigella flexneri 2a str. 301, complete genomeputative membrane transport protein6e-85314
NC_011751:3453683:3492377349237734935701194Escherichia coli UMN026 chromosome, complete genomeputative membrane transport protein, major facilitator superfamily5e-84311
CP002797:4812799:4814659481465948158521194Escherichia coli NA114, complete genomePutative membrane transport protein9e-84310
NC_011745:4862218:486676848667684867505738Escherichia coli ED1a chromosome, complete genome4e-49195
NC_011745:4862218:487805348780534878553501Escherichia coli ED1a chromosome, complete genome2e-30133
NC_015387:2072237:2085508208550820867041197Marinithermus hydrothermalis DSM 14884 chromosome, complete genomemajor facilitator superfamily MFS_14e-1066.2
NC_014315:1396990:1402492140249214036701179Nitrosococcus watsoni C-113 chromosome, complete genomemajor facilitator superfamily protein6e-0858.9
NC_007484:2045500:2056438205643820576251188Nitrosococcus oceani ATCC 19707, complete genomehypothetical protein1e-0758.2