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Query: NC_017168:2626996:2647378 Yersinia pestis A1122 chromosome, complete genome

Start: 2647378, End: 2647914, Length: 537

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017154:3188795:320917732091773209755579Yersinia pestis D106004 chromosome, complete genomephosphodiesterase2e-98357
NC_014029:3245778:326616232661623266713552Yersinia pestis Z176003 chromosome, complete genomehypothetical protein5e-89326
NC_015224:3225000:322929932292993229853555Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,hypothetical protein2e-76284
NC_008800:1459015:147679514767951477349555Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,hypothetical protein6e-76283
NC_012779:2586175:260189026018902602453564Edwardsiella ictaluri 93-146, complete genomehypothetical protein1e-49195
NC_015424:2917817:293110429311042931646543Aeromonas veronii B565 chromosome, complete genomephosphodiesterase YfcE2e-40164
NC_010520:1146000:115554911555491156094546Clostridium botulinum A3 str. Loch Maree, complete genomephosphodiesterase, MJ0936 family3e-40164
NC_012658:1052957:106015510601551060700546Clostridium botulinum Ba4 str. 657 chromosome, complete genomephosphodiesterase8e-39159
NC_010001:4586000:458620945862094586772564Clostridium phytofermentans ISDg, complete genomephosphodiesterase, MJ0936 family1e-28125
NC_009828:469778:488583488583489137555Thermotoga lettingae TMO, complete genomephosphodiesterase, MJ0936 family6e-2096.7
NC_018870:1417851:142244514224451423008564Thermacetogenium phaeum DSM 12270 chromosome, complete genomeputative phosphodiesterase YfcE3e-1891.7
NC_011653:1463743:148041414804141480968555Thermosipho africanus TCF52B, complete genomephosphodiesterase, family9e-1889.7
NC_011661:1100576:110651411065141107056543Dictyoglomus turgidum DSM 6724, complete genomephosphodiesterase, MJ0936 family1e-1685.9
NC_021171:2562000:256422525642252564773549Bacillus sp. 1NLA3E, complete genomephosphodiesterase2e-1685.1
NC_014209:761832:769761769761770303543Thermoanaerobacter mathranii subsp. mathranii str. A3 chromosome,phosphodiesterase, MJ0936 family3e-1684.3
NC_009718:1272296:127409312740931274683591Fervidobacterium nodosum Rt17-B1, complete genomephosphodiesterase2e-1479