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Query: NC_017168:2626996:2646608 Yersinia pestis A1122 chromosome, complete genome

Start: 2646608, End: 2647156, Length: 549

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_008800:1459015:147742114774211477969549Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,hypothetical protein1e-83308
NC_014029:3245778:326539232653923265940549Yersinia pestis Z176003 chromosome, complete genomehypothetical protein1e-87322
NC_017154:3188795:320840732084073208955549Yersinia pestis D106004 chromosome, complete genomehypothetical protein1e-87322
NC_012779:2586175:260127326012732601791519Edwardsiella ictaluri 93-146, complete genomehypothetical protein1e-58225
NC_015224:3225000:322867932286793229227549Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,hypothetical protein7e-83305
NC_012796:2041579:204480920448092045363555Desulfovibrio magneticus RS-1, complete genomeisopentenyl-diphosphate delta-isomerase family protein2e-0858.9
NC_009439:794498:814201814201814737537Pseudomonas mendocina ymp, complete genomeNUDIX hydrolase7e-1786.7
NC_016629:3396500:340510634051063405669564Desulfovibrio africanus str. Walvis Bay chromosome, completeNUDIX hydrolase6e-0753.9
NC_013093:2471574:247335624733562473865510Actinosynnema mirum DSM 43827, complete genomeNUDIX hydrolase6e-0857