Pre_GI: BLASTP Hits

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Query: NC_017168:2626996:2635203 Yersinia pestis A1122 chromosome, complete genome

Start: 2635203, End: 2635385, Length: 183

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:1765399:178137617813761781624249Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein1e-1891.7
NC_017265:1571305:158854115885411588723183Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein2e-1788.2
NC_017168:2394079:240132624013262401442117Yersinia pestis A1122 chromosome, complete genomehypothetical protein2e-0960.8
NC_017265:1346685:135302113530211353182162Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein1e-1891.7
NC_017265:1521276:154183615418361542003168Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein4e-1889.7
NC_005810:2549680:257058225705822570764183Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein2e-1788.2
NC_010634:1175404:120805312080531208310258Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein4e-1993.2
NC_009708:1735903:175540317554031755585183Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein2e-1890.9
NC_003143:2804500:280452828045282804710183Yersinia pestis CO92, complete genomehypothetical protein2e-1788.2
NC_017168:2892000:291102029110202911142123Yersinia pestis A1122 chromosome, complete genomehypothetical protein1e-0858.9
NC_017168:2281040:231529523152952315552258Yersinia pestis A1122 chromosome, complete genomehypothetical protein4e-1993.2
NC_017168:3290380:329590632959063296154249Yersinia pestis A1122 chromosome, complete genomehypothetical protein1e-1891.7
NC_017168:2941938:295772629577262957908183Yersinia pestis A1122 chromosome, complete genomehypothetical protein2e-1788.2
NC_017168:2560000:257681025768102576911102Yersinia pestis A1122 chromosome, complete genomehypothetical protein3e-0960.8