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Query: NC_017168:2626996:2629536 Yersinia pestis A1122 chromosome, complete genome

Start: 2629536, End: 2630066, Length: 531

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017154:3188795:319133531913353191865531Yersinia pestis D106004 chromosome, complete genomehypothetical protein6e-100362
NC_005810:1230976:124559312455931246123531Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein6e-100362
NC_008149:1195614:119815411981541198684531Yersinia pestis Nepal516, complete genomemembrane protein6e-100362
NC_008150:2822689:283863028386302839160531Yersinia pestis Antiqua, complete genomehypothetical protein6e-100362
NC_003143:3115933:313235831323583132888531Yersinia pestis CO92, complete genomehypothetical protein6e-100362
NC_004088:1265730:126827012682701268800531Yersinia pestis KIM, complete genomehypothetical protein6e-100362
NC_014029:3245778:324831832483183248848531Yersinia pestis Z176003 chromosome, complete genomehypothetical protein6e-100362
NC_008570:3083850:308654530865453087042498Aeromonas hydrophila subsp. hydrophila ATCC 7966, complete genomehypothetical protein1e-24112
NC_015424:2726223:272946627294662729984519Aeromonas veronii B565 chromosome, complete genomemembrane protein9e-24109
NC_009052:2107692:211004121100412110556516Shewanella baltica OS155, complete genomehypothetical protein1e-22105
NC_013416:1783349:1796199179619917987662568Aggregatibacter actinomycetemcomitans D11S-1, complete genomehypothetical protein3e-1994.4
NC_014622:5553628:5573377557337755756232247Paenibacillus polymyxa SC2 chromosome, complete genomehypothetical protein2e-1581.6
NC_017138:2293576:2301605230160523037372133Bacillus megaterium WSH-002 chromosome, complete genomemembrane protein2e-0652.4