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Query: NC_017168:2560000:2577025 Yersinia pestis A1122 chromosome, complete genome

Start: 2577025, End: 2577978, Length: 954

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017154:2901300:291729629172962918249954Yersinia pestis D106004 chromosome, complete genomehypothetical protein5e-173606
NC_010159:409500:450729450729451682954Yersinia pestis Angola, complete genomesseB protein5e-173606
NC_010634:3269010:329132532913253292278954Yersinia pseudotuberculosis PB1/+, complete genomeSseB family protein5e-173606
NC_008150:2599661:261565626156562616609954Yersinia pestis Antiqua, complete genomehypothetical protein5e-173606
NC_009523:5475812:548285454828545483621768Roseiflexus sp. RS-1 chromosome, complete genomeSseB family protein3e-24112
NC_020541:1827689:183584618358461836580735Rhodanobacter sp. 2APBS1, complete genomeSseB protein4e-1065.5
NC_020541:1786500:180009818000981800841744Rhodanobacter sp. 2APBS1, complete genomeSseB protein9e-0961.2
NC_020541:4122852:413214641321464132880735Rhodanobacter sp. 2APBS1, complete genomeSseB protein9e-0857.8