Pre_GI: BLASTP Hits

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Query: NC_017168:2281040:2316361 Yersinia pestis A1122 chromosome, complete genome

Start: 2316361, End: 2317170, Length: 810

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009654:1729159:174988517498851750745861Marinomonas sp. MWYL1, complete genomeGumN family protein7e-0651.2
NC_017262:1913302:1929281192928119303421062Zymomonas mobilis subsp. mobilis ATCC 10988 chromosome, completeGumN family protein4e-1065.5
NC_010634:1175404:120911912091191209928810Yersinia pseudotuberculosis PB1/+, complete genomeGumN family protein1e-155548
NC_010159:1288000:132139813213981322207810Yersinia pestis Angola, complete genomeGumN family protein1e-155548
NC_014219:2253023:2269369226936922706131245Bacillus selenitireducens MLS10 chromosome, complete genomeGumN family protein2e-1169.7
NC_015424:3520783:356669835666983567600903Aeromonas veronii B565 chromosome, complete genomeGumN protein1e-1480.5
NC_015976:1893076:189307618930761894053978Sphingobium sp. SYK-6, complete genomeGumN-family protein6e-1168.2
NC_005810:872672:907893907893908702810Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein1e-155548
NC_006155:1191307:122657612265761227385810Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein1e-155548
NC_015224:1391088:141802214180221418831810Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,hypothetical protein1e-119429
NC_004088:1196875:123006012300601230869810Yersinia pestis KIM, complete genomeligase1e-155548