Pre_GI: BLASTP Hits

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Query: NC_017168:2281040:2315042 Yersinia pestis A1122 chromosome, complete genome

Start: 2315042, End: 2315281, Length: 240

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:3240379:324037932403793240618240Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein1e-37155
NC_006155:1191307:122525712252571225496240Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein1e-37155
NC_004088:1196875:122874112287411229025285Yersinia pestis KIM, complete genomehypothetical protein9e-38155
NC_010159:1288000:132007813200781320317240Yersinia pestis Angola, complete genomehypothetical protein1e-37155
NC_003143:3446740:344674034467403447024285Yersinia pestis CO92, complete genomehypothetical protein9e-38155
NC_008150:2878450:287845028784502878689240Yersinia pestis Antiqua, complete genomehypothetical protein1e-37155
NC_008149:1122693:115791511579151158154240Yersinia pestis Nepal516, complete genomehypothetical protein1e-37155
NC_005810:872672:906574906574906858285Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein9e-38155
NC_009381:3094939:309493930949393095178240Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein1e-37155
NC_010634:1175404:120780012078001208039240Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein1e-37155