Pre_GI: BLASTP Hits

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Query: NC_017168:2281040:2290401 Yersinia pestis A1122 chromosome, complete genome

Start: 2290401, End: 2290544, Length: 144

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_008150:2878450:290309729030972903240144Yersinia pestis Antiqua, complete genomehypothetical protein1e-2098.2
NC_008149:1122693:113205411320541132197144Yersinia pestis Nepal516, complete genomehypothetical protein1e-2098.2
NC_005810:872672:8819648819648831061143Yersinia pestis biovar Microtus str. 91001, complete genomeputative CDP-D-glucose-4,6-dehydratase9e-2095.5
NC_017265:3240379:3264087326408732651601074Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,UDP-glucose 4-epimerase1e-1995.5
NC_010634:1175404:1182733118273311838061074Yersinia pseudotuberculosis PB1/+, complete genomeCDP-glucose 4,6-dehydratase3e-1890.1
NC_006155:1191307:1200668120066812017411074Yersinia pseudotuberculosis IP 32953, complete genomeCDP-glucose 4,6-dehydratase3e-1890.1
NC_009708:3411153:3434682343468234358571176Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeCDP-glucose 4,6-dehydratase7e-1889.4
NC_010465:3465351:3488912348891234899851074Yersinia pseudotuberculosis YPIII, complete genomeCDP-glucose 4,6-dehydratase6e-1889.4
NC_004547:1600900:1615316161531616164221107Erwinia carotovora subsp. atroseptica SCRI1043, complete genomeCDP-glucose 4,6-dehydratase1e-1478.6
NC_015633:413587:4394274394274405301104Vibrio anguillarum 775 chromosome chromosome I, complete sequenceCDP-glucose 4,6-dehydratase2e-1477.8
NC_008800:3330944:3355978335597833570511074Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,CDP-glucose 4,6-dehydratase3e-1477
NC_012483:656397:6621226621226631981077Acidobacterium capsulatum ATCC 51196, complete genomeCDP-glucose 4,6-dehydratase5e-1476.6
NC_006511:854785:8652998652998663781080Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCCCDP-glucose 4,6-dehydratase6e-1476.3
NC_011147:854730:8652448652448663231080Salmonella enterica subsp. enterica serovar Paratyphi A strCDP-glucose 4,6-dehydratase5e-1476.3
NC_016860:2148535:2167807216780721688861080Salmonella enterica subsp. enterica serovar Typhimurium strCDP-glucose 4,6-dehydratase8e-1475.9
NC_016857:2150709:2169981216998121710601080Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74CDP glucose 4,6-dehydratase8e-1475.9
NC_016856:2204546:2223818222381822248971080Salmonella enterica subsp. enterica serovar Typhimurium str. 14028SCDP glucose 4,6-dehydratase8e-1475.9
NC_016810:2150709:2169981216998121710601080Salmonella enterica subsp. enterica serovar Typhimurium strCDP-glucose 4,6-dehydratase8e-1475.9
NC_011205:2283438:2303918230391823049971080Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853CDP-glucose 4,6-dehydratase8e-1475.9
NC_003197:2152994:2172266217226621733451080Salmonella typhimurium LT2, complete genomeCDP glucose 4,6-dehydratase8e-1475.9
NC_011083:2200613:2219885221988522209641080Salmonella enterica subsp. enterica serovar Heidelberg str. SL476,CDP-glucose 4,6-dehydratase8e-1475.9
NC_011080:2161696:2183705218370521847841080Salmonella enterica subsp. enterica serovar Newport str. SL254,CDP-glucose 4,6-dehydratase8e-1475.9
NC_013959:2892660:2914739291473929158181080Sideroxydans lithotrophicus ES-1 chromosome, complete genomeCDP-glucose 4,6-dehydratase8e-1475.9
NC_016863:2152739:2172011217201121730901080Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1CDP glucose 4,6-dehydratase8e-1475.9
NC_017046:2150072:2169344216934421704231080Salmonella enterica subsp. enterica serovar Typhimurium str. 798CDP-glucose 4,6-dehydratase8e-1475.9
NC_011094:2172271:2193808219380821948871080Salmonella enterica subsp. enterica serovar Schwarzengrund strCDP-glucose 4,6-dehydratase7e-1475.9
NC_016832:861956:8725498725498736281080Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12,CDP-glucose 4,6-dehydratase7e-1475.9
NC_003198:2109775:2130254213025421313331080Salmonella enterica subsp. enterica serovar Typhi str. CT18,CDP-glucose 4,6-dehydratase7e-1475.9
NC_004631:862002:8725958725958736741080Salmonella enterica subsp. enterica serovar Typhi Ty2, completeCDP-glucose 4,6-dehydratase7e-1475.9
NC_010102:861860:8724548724548735331080Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,hypothetical protein7e-1475.9
NC_011149:2110861:2130131213013121312101080Salmonella enterica subsp. enterica serovar Agona str. SL483,CDP-glucose 4,6-dehydratase7e-1475.9
NC_016831:854973:8655688655688666471080Salmonella enterica subsp. enterica serovar Gallinarum/pullorumCDP-glucose 4,6-dehydratase7e-1475.9
NC_011294:2156425:2176901217690121779801080Salmonella enterica subsp. enterica serovar Enteritidis strCDP-glucose 4,6-dehydratase7e-1475.9
NC_011274:2147427:2167909216790921689881080Salmonella enterica subsp. enterica serovar Gallinarum str. 287/91CDP-glucose 4,6-dehydratase7e-1475.9
NC_000911:352263:3543233543233554051083Synechocystis sp. PCC 6803, complete genomeCDP-glucose-4,6-dehydratase5e-1373.2
NC_017039:352263:3543233543233554051083Synechocystis sp. PCC 6803 substr. PCC-P, complete genomeCDP-glucose-4,6-dehydratase5e-1373.2
NC_017052:352251:3543113543113553931083Synechocystis sp. PCC 6803 substr. PCC-N, complete genomeCDP-glucose-4,6-dehydratase5e-1373.2
NC_017277:352263:3543233543233554051083Synechocystis sp. PCC 6803, complete genomeCDP-glucose-4,6-dehydratase5e-1373.2
NC_007404:1964935:1977449197744919785251077Thiobacillus denitrificans ATCC 25259, complete genomeCDP-glucose 4,6-dehydratase4e-1373.2
NC_016616:49388:6844568445695091065Dechlorosoma suillum PS chromosome, complete genomeCDP-glucose 4,6-dehydratase9e-1372.4
NC_008609:3672653:3696948369694836980241077Pelobacter propionicus DSM 2379, complete genomeCDP-glucose 4,6-dehydratase1e-1272
NC_015942:1167785:1185313118531311863951083Acidithiobacillus ferrivorans SS3 chromosome, complete genomeCDP-glucose 4,6-dehydratase1e-1272
NC_010551:2537876:2554400255440025554851086Burkholderia ambifaria MC40-6 chromosome 1, complete sequenceCDP-glucose 4,6-dehydratase1e-1271.6
NC_014394:3036758:3062112306211230631881077Gallionella capsiferriformans ES-2 chromosome, complete genomeCDP-glucose 4,6-dehydratase2e-1270.9
NC_010531:292044:2944392944392955331095Polynucleobacter necessarius STIR1, complete genomeCDP-glucose 4,6-dehydratase4e-1270.1
NC_005296:4574213:4581052458105245821461095Rhodopseudomonas palustris CGA009, complete genomecdp-glucose 4,6-dehydratase4e-1270.1
NC_004129:5846415:5855956585595658570411086Pseudomonas fluorescens Pf-5, complete genomeCDP-glucose-4,6-dehydratase5e-1269.7
NC_012559:2563922:2582875258287525839331059Laribacter hongkongensis HLHK9, complete genomeRfbG1e-1168.9
NC_011027:1570955:1585246158524615863281083Chlorobaculum parvum NCIB 8327, complete genomeCDP-glucose 4,6-dehydratase1e-1168.6
NC_013851:2211120:2211916221191622129711056Allochromatium vinosum DSM 180 chromosome, complete genomeCDP-glucose 4,6-dehydratase2e-1167.8
NC_008570:4594436:4613869461386946149361068Aeromonas hydrophila subsp. hydrophila ATCC 7966, complete genomeCDP-glucose 4,6-dehydratase3e-1167.4
NC_017082:2355221:2370199237019923712661068Bradyrhizobium sp. S23321, complete genomeputative CDP-D-glucose-4,6-dehydratase4e-1167
NC_010814:794211:8033518033518044241074Geobacter lovleyi SZ, complete genomeCDP-glucose 4,6-dehydratase5e-1166.6
NC_016803:1027017:1054647105464710557411095Desulfovibrio desulfuricans ND132 chromosome, complete genomeCDP-glucose 4,6-dehydratase2e-1064.3
NC_011369:4395773:4395773439577343968371065Rhizobium leguminosarum bv. trifolii WSM2304 chromosome, completeCDP-glucose 4,6-dehydratase4e-1063.5
NC_011832:2306341:2330830233083023319271098Candidatus Methanosphaerula palustris E1-9c, complete genomeCDP-glucose 4,6-dehydratase3e-1063.5
NC_014844:3538432:3544885354488535459401056Desulfovibrio aespoeensis Aspo-2 chromosome, complete genomeCDP-glucose 4,6-dehydratase6e-1062.8
NC_017200:3221508:3239605323960532406601056Bacillus thuringiensis serovar finitimus YBT-020 chromosome,CDP-glucose 4,6-dehydratase9e-1062.4
NC_011658:3144000:3161165316116531622201056Bacillus cereus AH187 chromosome, complete genomeCDP-glucose 4,6-dehydratase9e-1062.4
NC_011969:3106500:3123326312332631243811056Bacillus cereus Q1 chromosome, complete genomecdp-glucose 4,6-dehydratase9e-1062.4
NC_016771:3097173:3115324311532431163791056Bacillus cereus NC7401, complete genomeCDP-glucose 4,6-dehydratase9e-1062.4
NC_011725:3231859:3250570325057032516251056Bacillus cereus B4264 chromosome, complete genomeCDP-glucose 4,6-dehydratase8e-1062.4
NC_014935:1999653:2006804200680420078681065Nitratifractor saLSUginis DSM 16511 chromosome, complete genomecdp-glucose 4,6-dehydratase8e-1062.4
NC_011979:2352961:2358072235807223591691098Geobacter sp. FRC-32, complete genomeCDP-glucose 4,6-dehydratase8e-1062.4
NC_004722:3303264:3321943332194333229981056Bacillus cereus ATCC 14579, complete genomeCDP-glucose 4,6-dehydratase8e-1062.4
NC_010645:1341475:1347809134780913488941086Bordetella avium 197N, complete genomeCDP-glucose 4,6-dehydratase7e-1062.4
NC_014010:1020488:1035015103501510360821068Candidatus Puniceispirillum marinum IMCC1322 chromosome, completeCDP-glucose 4,6-dehydratase1e-0962
NC_007759:2638992:2655417265541726565411125Syntrophus aciditrophicus SB, complete genomeCDP-glucose 4,6-dehydratase1e-0961.6
NC_015717:1723047:1725052172505217261341083Hyphomicrobium sp. MC1, complete genomecdp-glucose 4,6-dehydratase1e-0961.6
NC_007604:41495:6136661366624721107Synechococcus elongatus PCC 7942, complete genomeCDP-glucose 4,6-dehydratase1e-0961.6
NC_006576:1551939:1558411155841115595171107Synechococcus elongatus PCC 6301, complete genomeCDP-glucose 4,6-dehydratase2e-0961.2
NC_013037:5536433:5558289555828955593681080Dyadobacter fermentans DSM 18053, complete genomeCDP-glucose 4,6-dehydratase2e-0961.2
NC_008228:3679949:3695867369586736969251059Pseudoalteromonas atlantica T6c, complete genomeCDP-glucose 4,6-dehydratase3e-0960.5
NC_008942:1446682:1453931145393114550161086Methanocorpusculum labreanum Z, complete genomehypothetical protein5e-0959.7
NC_008313:3112440:3126242312624231273241083Ralstonia eutropha H16 chromosome 1, complete sequenceNAD dependent sugar epimerase6e-0959.7
NC_015577:3113907:3136323313632331373991077Treponema azotonutricium ZAS-9 chromosome, complete genomeCDP-glucose 4,6-dehydratase8e-0959.3
NC_014655:2705482:2710039271003927111091071Leadbetterella byssophila DSM 17132 chromosome, complete genomecdp-glucose 4,6-dehydratase9e-0958.9
NC_016776:4115889:4120862412086241219831122Bacteroides fragilis 638R, complete genomeputative LPS biosynthesis DNTP-hexose dehydratase-epimerase1e-0858.5
NC_014652:1091610:1106913110691311079891077Caldicellulosiruptor hydrothermalis 108 chromosome, completecdp-glucose 4,6-dehydratase1e-0858.5
NC_014033:522363:5282635282635293391077Prevotella ruminicola 23 chromosome, complete genomeCDP-D-glucose-4,6-dehydratase1e-0858.5
NC_014624:2211771:2216049221604922171761128Eubacterium limosum KIST612 chromosome, complete genomehypothetical protein3e-0857.4
NC_014802:1392831:1398887139888713999571071Campylobacter jejuni subsp. jejuni ICDCCJ07001 chromosome, completeCDP-glucose 4,6-dehydratase3e-0857.4
NC_016948:3381848:3408163340816334092571095Mycobacterium intracellulare MOTT-64 chromosome, complete genomeNAD-dependent epimerase/dehydratase3e-0857.4
NC_016947:3309898:3336148333614833372421095Mycobacterium intracellulare MOTT-02 chromosome, complete genomeNAD-dependent epimerase/dehydratase3e-0857
NC_014758:1207894:1223095122309512241681074Calditerrivibrio nitroreducens DSM 19672 chromosome, completecdp-glucose 4,6-dehydratase5e-0856.6
NC_017068:638868:6552156552156562761062Selenomonas ruminantium subsp. lactilytica TAM6421, completeputative CDP-glucose 4,6-dehydratase6e-0856.2
NC_005773:1135374:1139722113972211408041083Pseudomonas syringae pv. phaseolicola 1448A, complete genomeCDP-glucose-4,6-dehydratase1e-0755.5
NC_009484:661089:6657926657926668681077Acidiphilium cryptum JF-5 chromosome, complete genomeCDP-glucose 4,6-dehydratase2e-0754.3
NC_015186:755000:7579417579417590171077Acidiphilium multivorum AIU301, complete genomeCDP-glucose 4,6-dehydratase2e-0754.3
NC_014506:1482401:1487353148735314884471095Sulfurimonas autotrophica DSM 16294 chromosome, complete genomeCDP-glucose 4,6-dehydratase2e-0754.3
NC_013860:171235:1797091797091808181110Azospirillum sp. B510 plasmid pAB510f, complete sequenceCDP-glucose 4,6-dehydratase7e-0752.8
NC_007964:3036771:3051447305144730525201074Nitrobacter hamburgensis X14, complete genomeNAD-dependent epimerase/dehydratase1e-0651.6
NC_007954:3171081:3187472318747231885721101Shewanella denitrificans OS217, complete genomeNAD-dependent epimerase/dehydratase2e-0651.6
NC_007955:1664998:1683455168345516845701116Methanococcoides burtonii DSM 6242, complete genomeNAD-dependent epimerase/dehydratase4e-0650.4
NC_015500:987641:9900049900049910681065Treponema brennaborense DSM 12168 chromosome, complete genomeCDP-glucose 4,6-dehydratase6e-0649.7
NC_007908:1328832:1344920134492013460231104Rhodoferax ferrireducens T118, complete genomeNAD-dependent epimerase/dehydratase9e-0648.9