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Query: NC_017168:1631052:1649208 Yersinia pestis A1122 chromosome, complete genome

Start: 1649208, End: 1649399, Length: 192

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:4265659:426900742690074269198192Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein8e-30129
NC_008149:4053363:406489540648954065086192Yersinia pestis Nepal516, complete genomehypothetical protein8e-30129
NC_003143:4006884:402504040250404025231192Yersinia pestis CO92, complete genomehypothetical protein8e-30129
NC_004088:266543:278074278074278265192Yersinia pestis KIM, complete genomehypothetical protein8e-30129
NC_005810:4469156:448088144808814481072192Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein8e-30129
NC_009381:222735:240870240870241061192Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein8e-30129
NC_006155:4302826:430609543060954306448354Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein4e-1683.2
NC_010465:429095:447924447924448286363Yersinia pseudotuberculosis YPIII, complete genomeDomain of unknown function DUF1813, HSP20-like protein6e-1579.3
NC_004547:3817656:382144138214413821785345Erwinia carotovora subsp. atroseptica SCRI1043, complete genomehypothetical protein4e-0856.6
NC_004547:3817656:382837138283713828715345Erwinia carotovora subsp. atroseptica SCRI1043, complete genomeconserved hypothetical protei1e-0652