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Query: NC_017168:144000:153665 Yersinia pestis A1122 chromosome, complete genome

Start: 153665, End: 154522, Length: 858

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009381:720000:729658729658730515858Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein7e-168589
NC_005810:4045303:405571040557104056567858Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein7e-168589
NC_015563:4093650:410157341015734102244672Delftia sp. Cs1-4 chromosome, complete genomehypothetical protein5e-1168.6
NC_014365:3123853:3123853312385331249171065Desulfarculus baarsii DSM 2075 chromosome, complete genomehypothetical protein6e-1065.1