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Query: NC_017168:144000:152241 Yersinia pestis A1122 chromosome, complete genome

Start: 152241, End: 152561, Length: 321

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009381:720000:728234728234728554321Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein3e-56216
NC_005810:4045303:405767140576714057991321Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein3e-56216
NC_018691:3082000:308567130856713086006336Alcanivorax dieselolei B5 chromosome, complete genomehypothetical protein4e-1063.5
NC_017059:1727095:173082517308251731103279Rhodospirillum photometricum DSM 122, complete genomehypothetical protein3e-0960.8