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Query: NC_017168:144000:149485 Yersinia pestis A1122 chromosome, complete genome

Start: 149485, End: 150252, Length: 768

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009381:720000:725462725462726229768Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein6e-140496
NC_014500:177824:178969178969179742774Dickeya dadantii 3937 chromosome, complete genomehypothetical protein1e-61236
NC_009439:442890:447247447247448011765Pseudomonas mendocina ymp, complete genomehypothetical protein2e-48192
NC_014013:112008:124600124600125337738Sphingobium japonicum UT26S chromosome 2, complete genomehypothetical protein2e-32139