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Query: NC_017168:144000:145845 Yersinia pestis A1122 chromosome, complete genome

Start: 145845, End: 146039, Length: 195

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009381:720000:721822721822722016195Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein4e-31133
NC_005810:4045303:406419340641934064387195Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein4e-31133
NC_004547:1873390:191988219198821920076195Erwinia carotovora subsp. atroseptica SCRI1043, complete genomehypothetical protein3e-21100
NC_007347:3188614:319522931952293195447219Ralstonia eutropha JMP134 chromosome 1, complete sequencehypothetical protein3e-1373.9
NC_015519:1081539:110052411005241100736213Tepidanaerobacter sp. Re1 chromosome, complete genomehypothetical protein3e-1373.9
NC_015437:1494777:149906414990641499255192Selenomonas sputigena ATCC 35185 chromosome, complete genomehypothetical protein1e-1168.6
NC_008600:1071537:107587310758731076139267Bacillus thuringiensis str. Al Hakam, complete genomehypothetical protein2e-1167.8
NC_018750:5078705:509100950910095091389381Streptomyces venezuelae ATCC 10712, complete genomehypothetical protein4e-1063.2
NC_011725:1055552:106182610618261062092267Bacillus cereus B4264 chromosome, complete genomehypothetical protein1e-0962
NC_004722:1033000:103547210354721035738267Bacillus cereus ATCC 14579, complete genomehypothetical protein1e-0962
NC_015514:181773:193763193763194143381Cellulomonas fimi ATCC 484 chromosome, complete genomehypothetical protein1e-0961.6
NC_014171:1043961:105023510502351050501267Bacillus thuringiensis BMB171 chromosome, complete genomehypothetical protein2e-0961.6
NC_013730:3863581:386987238698723870141270Spirosoma linguale DSM 74, complete genomehydrolase5e-0959.7
NC_010184:1048559:105197910519791052245267Bacillus weihenstephanensis KBAB4, complete genomehypothetical protein6e-0959.3
NC_015514:3877810:389300638930063893386381Cellulomonas fimi ATCC 484 chromosome, complete genomehypothetical protein9e-0958.9
NC_013202:418500:421963421963422265303Halomicrobium mukohataei DSM 12286, complete genomehypothetical protein1e-0755.5
NC_013740:1218429:124977712497771249980204Acidaminococcus fermentans DSM 20731, complete genomehypothetical protein1e-0652
NC_011830:720756:735978735978736319342Desulfitobacterium hafniense DCB-2, complete genomehypothetical protein1e-0651.6