Pre_GI: BLASTP Hits

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Query: NC_017160:676249:692288 Yersinia pestis D182038 chromosome, complete genome

Start: 692288, End: 692602, Length: 315

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_006155:4062000:4063950406395040653261377Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein1e-47187
NC_005810:3272765:3286599328659932879811383Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein2e-47187
NC_008149:587689:6052996052996066811383Yersinia pestis Nepal516, complete genomehypothetical protein2e-47187
NC_008150:3495851:3496330349633034977121383Yersinia pestis Antiqua, complete genomehypothetical protein2e-47187
NC_003143:675622:6957286957286971101383Yersinia pestis CO92, complete genomehypothetical protein2e-47187
NC_004088:3923804:3925388392538839267701383Yersinia pestis KIM, complete genomehypothetical protein2e-47187
NC_009381:460358:4776954776954790771383Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein2e-47187
NC_014029:729675:7472787472787486601383Yersinia pestis Z176003 chromosome, complete genomehypothetical protein2e-47187
NC_017154:671816:6894306894306908121383Yersinia pestis D106004 chromosome, complete genomehypothetical protein2e-47187
NC_017265:3790750:3790750379075037921321383Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein2e-47187
NC_009708:633054:6461986461986473761179Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeHNH endonuclease domain-containing protein3e-47186
NC_010465:660207:6733476733476745251179Yersinia pseudotuberculosis YPIII, complete genomeHNH endonuclease4e-47186
NC_010634:4001154:4004156400415640055321377Yersinia pseudotuberculosis PB1/+, complete genomeHNH endonuclease4e-47186