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Query: NC_017160:676249:677779 Yersinia pestis D182038 chromosome, complete genome

Start: 677779, End: 679680, Length: 1902

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:3790750:3804066380406638059671902Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein01215
NC_008149:587689:5914675914675933681902Yersinia pestis Nepal516, complete genomemembrane protein01215
NC_004088:3923804:3938705393870539406061902Yersinia pestis KIM, complete genomehypothetical protein01215
NC_008150:3495851:3511606351160635135071902Yersinia pestis Antiqua, complete genomehypothetical protein01215
NC_009381:460358:4618894618894637901902Yersinia pestis Pestoides F chromosome, complete genomemembrane protein01215
NC_014029:729675:7334537334537353541902Yersinia pestis Z176003 chromosome, complete genomehypothetical protein01215
NC_017154:671816:6755946755946774951902Yersinia pestis D106004 chromosome, complete genomehypothetical protein01215
NC_010634:4001154:4017524401752440194251902Yersinia pseudotuberculosis PB1/+, complete genomefusaric acid resistance protein region01213
NC_009708:633054:6330546330546349551902Yersinia pseudotuberculosis IP 31758 chromosome, complete genomefusaric acid resistance domain-containing protein01211
NC_010465:660207:6602076602076621081902Yersinia pseudotuberculosis YPIII, complete genomeFusaric acid resistance protein conserved region01211
NC_006155:4062000:4077291407729140791921902Yersinia pseudotuberculosis IP 32953, complete genomepossible PET family efflux transporter01208
NC_005810:3272765:3272765327276532745851821Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein01160
NC_003143:675622:6799336799336817021770Yersinia pestis CO92, complete genomehypothetical protein01127
NC_007511:1147696:1181039118103911833602322Burkholderia sp. 383 chromosome 2, complete sequencemembrane protein-like2e-62240
NC_007509:3668:3972439724418502127Burkholderia sp. 383 chromosome 3, complete sequenceFusaric acid resistance protein1e-47191
CP002185:4566150:4566150456615045682012052Escherichia coli W, complete genomepredicted outer membrane factor of efflux pump2e-36154
NC_013364:5040268:5040268504026850423192052Escherichia coli O111:H- str. 11128, complete genomeputative multidrug efflux system component3e-36153
NC_009800:4332229:4332229433222943342802052Escherichia coli HS, complete genomemultidrug resistance protein MdtO2e-35151
NC_007613:4156841:4156841415684141587511911Shigella boydii Sb227, complete genomeputative enzyme8e-32139
NC_015376:2010009:2036959203695920391482190Burkholderia gladioli BSR3 chromosome chromosome 2, completefusaric acid resistance protein region2e-28128
NC_010515:2691000:2722322272232227243882067Burkholderia cenocepacia MC0-3 chromosome 2, complete sequencefusaric acid resistance protein conserved region2e-25118