Pre_GI: BLASTP Hits

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Query: NC_017160:676249:676249 Yersinia pestis D182038 chromosome, complete genome

Start: 676249, End: 677610, Length: 1362

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:3790750:3805972380597238074981527Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein0859
NC_008149:587689:5899365899365914621527Yersinia pestis Nepal516, complete genomemembrane protein0859
NC_010634:4001154:4019430401943040209561527Yersinia pseudotuberculosis PB1/+, complete genomeouter membrane efflux protein0859
NC_008150:3495851:3513512351351235150381527Yersinia pestis Antiqua, complete genomehypothetical protein0859
NC_006155:4062000:4079197407919740807231527Yersinia pseudotuberculosis IP 32953, complete genomepossible Outer Membrane Factor (OMF) Family efflux porin0859
NC_004088:3923804:3940611394061139421371527Yersinia pestis KIM, complete genomehypothetical protein0859
NC_003143:675622:6784026784026799281527Yersinia pestis CO92, complete genomehypothetical protein0859
NC_010159:1071937:1086543108654310879041362Yersinia pestis Angola, complete genomeouter membrane efflux protein0858
NC_014029:729675:7319227319227332831362Yersinia pestis Z176003 chromosome, complete genomeouter membrane efflux protein0858
NC_017154:671816:6740636740636754241362Yersinia pestis D106004 chromosome, complete genomeouter membrane efflux protein0858
NC_009381:460358:4603584603584618841527Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein0854
NC_007511:1147696:1179508117950811810521545Burkholderia sp. 383 chromosome 2, complete sequenceouter membrane efflux protein1e-80300
NC_015376:2010009:2039135203913520406941560Burkholderia gladioli BSR3 chromosome chromosome 2, completeouter membrane efflux protein2e-78293
NC_010515:2691000:2720791272079127223351545Burkholderia cenocepacia MC0-3 chromosome 2, complete sequenceouter membrane efflux protein2e-77290
NC_011206:1719000:1735364173536417375802217Acidithiobacillus ferrooxidans ATCC 53993, complete genomeouter membrane efflux protein1e-20101
NC_010002:3357752:3363415336341533648721458Delftia acidovorans SPH-1, complete genomeouter membrane efflux protein2e-1997.4
NC_009254:637952:6384836384836399581476Burkholderia vietnamiensis G4 chromosome 3, complete sequenceFis family transcriptional regulator5e-1892.8
NC_015856:3170771:3176279317627931777781500Collimonas fungivorans Ter331 chromosome, complete genomeouter membrane efflux protein6e-1375.9
NC_012691:2614603:2689453268945326909401488Tolumonas auensis DSM 9187, complete genomeRND efflux system, outer membrane lipoprotein, NodT family1e-1171.2
NC_011296:1542835:1554245155424515556421398Thermodesulfovibrio yellowstonii DSM 11347, complete genomeouter membrane protein OprM1e-1171.2
NC_014931:1642179:1661746166174616631851440Variovorax paradoxus EPS chromosome, complete genomeRND efflux system, outer membrane lipoprotein, NodT family4e-1169.7
NC_009659:1129066:1154914115491411563441431Janthinobacterium sp. Marseille chromosome, complete genomeouter membrane protein1e-1068.6
NC_015761:299386:3484843484843499411458Salmonella bongori NCTC 12419, complete genomecation transport lipoprotein2e-1067.4
NC_016112:1735044:1756944175694417583201377Methylomicrobium alcaliphilum chromosome, complete genomeNodT family RND efflux system outer membrane lipoprotein5e-1066.2
NC_011296:102650:1213371213371225961260Thermodesulfovibrio yellowstonii DSM 11347, complete genomeouter membrane efflux protein2e-0963.9
NC_004547:3866439:3865039386503938664421404Erwinia carotovora subsp. atroseptica SCRI1043, complete genomemultidrug resistance outer membrane protein3e-0963.5
NC_015572:2713599:2730670273067027320071338Methylomonas methanica MC09 chromosome, complete genomeNodT family RND efflux system outer membrane lipoprotein3e-0963.5
NC_011761:1904637:1921986192198619234761491Acidithiobacillus ferrooxidans ATCC 23270 chromosome, completeouter membrane toxin secretion efflux protein5e-0962.8
NC_011206:1792621:1807632180763218091221491Acidithiobacillus ferrooxidans ATCC 53993, complete genomeouter membrane efflux protein5e-0962.8
CU928145:3983432:3985219398521939869071689Escherichia coli 55989 chromosome, complete genomeputative outer membrane lipoprotein silC precursor1e-0861.6
NC_011748:3983432:3985219398521939869071689Escherichia coli 55989, complete genomecopper/silver efflux system outer membrane protein CusC1e-0861.6
NC_010170:4409683:4430706443070644321691464Bordetella petrii, complete genomeprobable outer membrane efflux protein1e-0861.6
NC_009778:4188000:4203563420356342049481386Enterobacter sakazakii ATCC BAA-894, complete genomehypothetical protein2e-0861.2
NC_009943:677324:6894536894536908471395Candidatus Desulfococcus oleovorans Hxd3, complete genometype I secretion outer membrane protein, TolC family2e-0861.2
NC_009348:1475955:1479091147909114804971407Aeromonas salmonicida subsp. salmonicida A449, complete genomeouter membrane protein OprM2e-0860.8
NC_015727:1357095:1369543136954313709641422Cupriavidus necator N-1 plasmid BB1p, complete sequencefusaric acid resistance protein FusA4e-0859.7
NC_014758:579741:6004736004736018941422Calditerrivibrio nitroreducens DSM 19672 chromosome, completernd efflux system, outer membrane lipoprotein, nodt family6e-0859.3
NC_004578:5623783:5648897564889756503361440Pseudomonas syringae pv. tomato str. DC3000, complete genomeouter membrane efflux protein TolC, putative7e-0858.9
NC_013520:1559000:1564721156472115664211701Veillonella parvula DSM 2008, complete genomeRND efflux system, outer membrane lipoprotein, NodT family1e-0757.8
NC_016002:2453919:2476508247650824779741467Pseudogulbenkiania sp. NH8B, complete genomecation/multidrug efflux system, outer membrane channel TolC2e-0757.8
NC_008570:3220539:3268759326875932701741416Aeromonas hydrophila subsp. hydrophila ATCC 7966, complete genomeouter membrane protein OprM3e-0757
NC_007973:1821753:1825603182560318271531551Ralstonia metallidurans CH34 chromosome 1, complete sequenceRND efflux system, outer membrane lipoprotein, NodT3e-0757
NC_012660:4558122:4556731455673145581251395Pseudomonas fluorescens SBW25 chromosome, complete genomeouter membrane efflux lipoprotein3e-0757
NC_010102:2721374:2724525272452527260151491Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,hypothetical protein5e-0756.2
NC_007973:1821753:1846301184630118477611461Ralstonia metallidurans CH34 chromosome 1, complete sequenceRND efflux system, outer membrane lipoprotein, NodT9e-0755.5
NC_014926:819163:8191638191638204521290Thermovibrio ammonificans HB-1 chromosome, complete genomeouter membrane efflux protein9e-0755.5
NC_010170:4463000:4477751447775144792231473Bordetella petrii, complete genomeprobable outer membrane efflux protein1e-0655.1
NC_009663:2056166:2064795206479520661891395Sulfurovum sp. NBC37-1, complete genomeouter membrane efflux lipoprotein1e-0655.1
NC_012489:3503632:3518589351858935200971509Gemmatimonas aurantiaca T-27, complete genomeouter membrane efflux protein1e-0654.7
NC_013722:1816561:1843038184303818445071470Xanthomonas albilineans, complete genomeputative outer membrane efflux protein2e-0654.3
NC_011080:383441:3968793968793983361458Salmonella enterica subsp. enterica serovar Newport str. SL254,outer membrane protein OprM2e-0654.3
NC_011146:2916223:2927604292760429291181515Geobacter bemidjiensis Bem, complete genomeRND efflux system, outer membrane lipoprotein, NodT family2e-0654.3
NC_011083:403022:4395464395464410031458Salmonella enterica subsp. enterica serovar Heidelberg str. SL476,outer membrane efflux protein OprA3e-0653.9
NC_010473:623810:6474156474156487881374Escherichia coli str. K-12 substr. DH10B, complete genomecopper/silver efflux system, outer membrane component5e-0653.1
NC_004663:1499145:1508365150836515097561392Bacteroides thetaiotaomicron VPI-5482, complete genomeouter membrane efflux protein4e-0653.1
NC_009615:2039964:2055548205554820569541407Parabacteroides distasonis ATCC 8503 chromosome, complete genomeouter membrane efflux protein oprM4e-0653.1
NC_011149:361765:3752163752163766731458Salmonella enterica subsp. enterica serovar Agona str. SL483,outer membrane protein OprM4e-0653.1
NC_012721:137046:1401291401291417151587Burkholderia glumae BGR1 chromosome 2, complete genomeOuter membrane protein5e-0652.8
NC_015424:3112637:3116924311692431182881365Aeromonas veronii B565 chromosome, complete genomeouter membrane efflux protein5e-0652.8
NC_012125:373630:3870683870683885251458Salmonella enterica subsp. enterica serovar Paratyphi C strainouter membrane efflux-like protein8e-0652.4
NC_014722:1084616:1107824110782411093291506Burkholderia rhizoxinica HKI 454, complete genomefusaric acid resistance protein fusA8e-0652.4
NC_011274:376970:3904073904073918641458Salmonella enterica subsp. enterica serovar Gallinarum str. 287/91outer membrane efflux lipoprotein9e-0652
NC_009883:1262000:1275208127520812765721365Rickettsia bellii OSU 85-389, complete genomeType I secretion outer membrane protein TolC9e-0652
NC_014926:1108811:1107565110756511089231359Thermovibrio ammonificans HB-1 chromosome, complete genomeouter membrane efflux protein1e-0552