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Query: NC_017160:4508000:4512666 Yersinia pestis D182038 chromosome, complete genome

Start: 4512666, End: 4513673, Length: 1008

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_008150:4634695:4634695463469546357021008Yersinia pestis Antiqua, complete genomeputative iron transport permease2e-166585
NC_010465:62348:7759177591785981008Yersinia pseudotuberculosis YPIII, complete genometransport system permease protein4e-166584
NC_013956:3273340:330119033011903302182993Pantoea ananatis LMG 20103 chromosome, complete genomeFatC2e-99362
NC_014829:405104:424192424192425139948Bacillus cellulosilyticus DSM 2522 chromosome, complete genometransport system permease protein1e-61236
NC_005955:1205836:122208312220831222958876Bartonella quintana str. Toulouse, complete genomeFerric anguibactin transport system permease protein4e-58225
NC_010161:1914000:193107419310741932024951Bartonella tribocorum CIP 105476, complete genomeferric anguibactin-transport system permease3e-56219
NC_012846:1837924:185435418543541855304951Bartonella grahamii as4aup, complete genomeferric anguibactin transport system permease protein6e-55214
NC_004193:375416:573234573234574190957Oceanobacillus iheyensis HTE831, complete genomeferrichrome ABC transporter permease4e-49195
NC_010120:199942:219789219789220763975Neisseria meningitidis 053442, complete genomeiron(III) ABC transporter, permease protein6e-49194
NC_010545:1089286:109045410904541091452999Corynebacterium urealyticum DSM 7109, complete genomeputative iron ABC transport system, permease protein9e-46184
NC_004668:2938000:295922929592292960194966Enterococcus faecalis V583, complete genomeiron compound ABC transporter, permease protein4e-45182
NC_017316:2466244:248685324868532487818966Enterococcus faecalis OG1RF chromosome, complete genomeferric (Fe+3) ABC superfamily ATP binding cassette transporter, membrane protein1e-44180
NC_015436:1287873:129061012906101291572963Spirochaeta coccoides DSM 17374 chromosome, complete genometransport system permease protein2e-42173
NC_010184:4879552:4878491487849148795551065Bacillus weihenstephanensis KBAB4, complete genometransport system permease protein5e-41168
NC_019897:763412:7861117861117871631053Thermobacillus composti KWC4 chromosome, complete genomeenterochelin ABC transporter permease3e-40166
NC_014532:2108897:213562521356252136572948Halomonas elongata DSM 2581, complete genomeABC-type transport system permease protein5e-35148
NC_015637:819233:819233819233820213981Vibrio anguillarum 775 chromosome chromosome II, complete sequenceFatC8e-33141
NC_005956:1455496:147123214712321472220989Bartonella henselae str. Houston-1, complete genome1e-1377.8
NC_008262:904000:9228629228629238751014Clostridium perfringens SM101, complete genomeferrichrome transport system, permease protein5e-0962
NC_003366:981105:9961049961049971171014Clostridium perfringens str. 13, complete genomeprobable ferrichrome ABC transporter1e-0861.2
NC_004193:375416:375416375416675301299886Oceanobacillus iheyensis HTE831, complete genome6e-0858.5
NC_011059:1391734:1417600141760014186881089Prosthecochloris aestuarii DSM 271, complete genometransport system permease protein2e-0653.5
NC_016023:1658377:1670706167070616717791074Bacillus coagulans 36D1 chromosome, complete genomeABC transporter integral membrane protein3e-0653.1